Genetic and environmental aspects of drug metabolism relevant to side-effects in arthritic disease

[1]  T. Shimada,et al.  Human-liver cytochromes P-450 involved in polymorphisms of drug oxidation. , 1986, Xenobiotica; the fate of foreign compounds in biological systems.

[2]  E. Spina,et al.  Oxidation of tricyclic antidepressant drugs, debrisoquine and 7-ethoxyresorufin, by human liver preparations. , 1986, Xenobiotica; the fate of foreign compounds in biological systems.

[3]  D. Parke,et al.  Liver function in patients on long‐term paracetamol (co‐proxamol) analgesia , 1986, The Journal of pharmacy and pharmacology.

[4]  Robert A. Lewis,et al.  Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function , 1985 .

[5]  D. Williams,et al.  A prostaglandin omega-hydroxylase cytochrome P-450 (P-450PG-omega) purified from lungs of pregnant rabbits. , 1984, The Journal of biological chemistry.

[6]  P. Emery,et al.  D-Penicillamine induced toxicity in rheumatoid arthritis: the role of sulphoxidation status and HLA-DR3. , 1984, The Journal of rheumatology.

[7]  C. Ioannides,et al.  Determination of cytochrome P-448 activity in biological tissues. , 1984, The Biochemical journal.

[8]  B. Halliwell,et al.  Lipid peroxidation in rheumatoid arthritis: thiobarbituric acid-reactive material and catalytic iron salts in synovial fluid from rheumatoid patients. , 1984, Clinical science.

[9]  R. E. Kouri,et al.  Variations in Aryl Hydrocarbon Hydroxylase Activities in Mitogen-Activated Human and Nonhuman Primate Lymphocytes , 1984, Toxicologic pathology.

[10]  D. Parke.  Survey of drug-metabolizing enzymes. , 1983, Biochemical Society transactions.

[11]  P. Dieppe,et al.  Effect of a specific iron chelating agent on animal models of inflammation. , 1983, Annals of the rheumatic diseases.

[12]  L. Marnett,et al.  Cytochrome P-450-dependent oxygenation of arachidonic acid to hydroxyicosatetraenoic acids. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[13]  P. Dieppe,et al.  THE IMPORTANCE OF IRON IN RHEUMATOID DISEASE , 1981, The Lancet.

[14]  M. Cawthorne,et al.  Adjuvant-induced arthritis and drug-metabolizing enzymes. , 1976, Biochemical pharmacology.

[15]  I. Leck,et al.  PREVALENCE AND DURATION OF UNDETECTED BREAST CANCER , 1975, The Lancet.

[16]  B B Brodie,et al.  Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione. , 1973, The Journal of pharmacology and experimental therapeutics.

[17]  M. Whitehouse,et al.  Effect of adjuvant disease in rats on cyclophosphamide and isophosphamide metabolism. , 1973, Biochemical pharmacology.

[18]  G. Gantner,et al.  D‐Penicillamine in rheumatoid arthritis , 1970 .

[19]  D. Morton,et al.  The effects of adjuvant-induced arthritis on the liver metabolism of drugs in rats. , 1970, Biochemical pharmacology.

[20]  H. Fuder,et al.  The determination of presynaptic KA values of methacholine and pilocarpine and of a presynaptic receptor reserve in the rat perfused heart. , 1985, British journal of pharmacology.

[21]  C. Ioannides,et al.  Cytochrome P-448 and the activation of toxic chemicals and carcinogens. , 1984, Xenobiotica; the fate of foreign compounds in biological systems.

[22]  M. Woodcock,et al.  Glutathione depletion enhances the lifetime of oxygen-reactive radicals in mammalian cells. , 1984, International journal of radiation biology and related studies in physics, chemistry, and medicine.

[23]  H. A. Masson,et al.  Metabolic activation of paracetamol by highly purified forms of cytochrome P-450. , 1983, Research communications in chemical pathology and pharmacology.

[24]  E. Jellum,et al.  D-penicillamine-induced increase in intracellular glutathione correlating to clinical response in rheumatoid arthritis. , 1981, The Journal of rheumatology. Supplement.

[25]  C. Witmer,et al.  Effects of a nonsteroidal anti-inflammatory agent and phenobarbital on hepatic microsomal mono-oxygenases in adjuvant disease in the rat. , 1978, Biochemical pharmacology.

[26]  S. Thorgeirsson,et al.  Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen. , 1974, Pharmacology.

[27]  J. Gillette,et al.  Microsomes and drug oxidations , 1968 .