Evaluation of Psn, HmuR and a modified LcrV protein delivered to mice by live attenuated Salmonella as a vaccine against bubonic and pneumonic Yersinia pestis challenge.

[1]  Wei Sun,et al.  Live Recombinant Salmonella Typhi Vaccines Constructed to Investigate the Role of rpoS in Eliciting Immunity to a Heterologous Antigen , 2010, PloS one.

[2]  B. Gunn,et al.  Construction of Recombinant Attenuated Salmonella enterica Serovar Typhimurium Vaccine Vector Strains for Safety in Newborn and Infant Mice , 2010, Clinical and Vaccine Immunology.

[3]  A. G. Bobrov,et al.  The Yersiniabactin Transport System Is Critical for the Pathogenesis of Bubonic and Pneumonic Plague , 2010, Infection and Immunity.

[4]  R. Perry,et al.  Yersinia ironomics: comparison of iron transporters among Yersiniapestis biotypes and its nearest neighbor, Yersinia pseudotuberculosis , 2010, BioMetals.

[5]  Wei Sun,et al.  Oral vaccination with LcrV from Yersinia pestis KIM delivered by live attenuated Salmonella enterica serovar Typhimurium elicits a protective immune response against challenge with Yersinia pseudotuberculosis and Yersinia enterocolitica. , 2009, Vaccine.

[6]  B. Gunn,et al.  Evaluation of new generation Salmonella enterica serovar Typhimurium vaccines with regulated delayed attenuation to induce immune responses against PspA , 2009, Proceedings of the National Academy of Sciences.

[7]  B. Gunn,et al.  Salmonella enterica Serovar Typhimurium Strains with Regulated Delayed Attenuation In Vivo , 2008, Infection and Immunity.

[8]  A. Lin,et al.  Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis. , 2008, Cell host & microbe.

[9]  B. Gunn,et al.  A sopB Deletion Mutation Enhances the Immunogenicity and Protective Efficacy of a Heterologous Antigen Delivered by Live Attenuated Salmonella enterica Vaccines , 2008, Infection and Immunity.

[10]  B. Gunn,et al.  Presence of Wild-Type and Attenuated Salmonella enterica Strains in Brain Tissues following Inoculation of Mice by Different Routes , 2008, Infection and Immunity.

[11]  R. Curtiss,et al.  Analysis of Type II Secretion of Recombinant Pneumococcal PspA and PspC in a Salmonella enterica Serovar Typhimurium Vaccine with Regulated Delayed Antigen Synthesis , 2008, Infection and Immunity.

[12]  V. Uversky,et al.  Attachment of LcrV from Yersinia pestis at dual binding sites to human TLR-2 and human IFN-gamma receptor. , 2007, Journal of proteome research.

[13]  Shixia Wang,et al.  Evaluation of the Role of LcrV-Toll-Like Receptor 2-Mediated Immunomodulation in the Virulence of Yersinia pestis , 2007, Infection and Immunity.

[14]  S. Crosby,et al.  Progression of primary pneumonic plague: a mouse model of infection, pathology, and bacterial transcriptional activity. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[15]  J. Heesemann,et al.  A hypervariable N-terminal region of Yersinia LcrV determines Toll-like receptor 2-mediated IL-10 induction and mouse virulence. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[16]  O. Schneewind,et al.  LcrV Plague Vaccine with Altered Immunomodulatory Properties , 2005, Infection and Immunity.

[17]  A. Sing,et al.  Yersinia V antigen induces both TLR homo- and heterotolerance in an IL-10-involving manner. , 2004, Cellular immunology.

[18]  R. Brubaker.  Interleukin-10 and Inhibition of Innate Immunity to Yersiniae: Roles of Yops and LcrV (V Antigen) , 2003, Infection and Immunity.

[19]  R. Perry,et al.  Yersinia pestis TonB: Role in Iron, Heme, and Hemoprotein Utilization , 2003, Infection and Immunity.

[20]  M. Aepfelbacher,et al.  Yersinia V–Antigen Exploits Toll-like Receptor 2 and CD14 for Interleukin 10–mediated Immunosuppression , 2002, The Journal of experimental medicine.

[21]  R. Curtiss.  Bacterial infectious disease control by vaccine development. , 2002, The Journal of clinical investigation.

[22]  R. Curtiss,et al.  Immune Responses to Recombinant Pneumococcal PspA Antigen Delivered by Live Attenuated Salmonella enterica Serovar Typhimurium Vaccine , 2002, Infection and Immunity.

[23]  J. Heesemann,et al.  Yersinia enterocolitica Evasion of the Host Innate Immune Response by V Antigen-Induced IL-10 Production of Macrophages Is Abrogated in IL-10-Deficient Mice1 , 2002, The Journal of Immunology.

[24]  S. Létoffé,et al.  Identification and Characterization of the Hemophore-Dependent Heme Acquisition System of Yersinia pestis , 2001, Infection and Immunity.

[25]  M. Simmonds,et al.  Genome sequence of Yersinia pestis, the causative agent of plague , 2001, Nature.

[26]  R. Titball,et al.  Vaccination against bubonic and pneumonic plague. , 2001, Vaccine.

[27]  K. A. Fields,et al.  Virulence Role of V Antigen of Yersinia pestis at the Bacterial Surface , 1999, Infection and Immunity.

[28]  R. Perry,et al.  Molecular Characterization of the Hemin Uptake Locus (hmu) from Yersinia pestis and Analysis ofhmu Mutants for Hemin and Hemoprotein Utilization , 1999, Infection and Immunity.

[29]  G. Cornelis,et al.  The Virulence Plasmid of Yersinia, an Antihost Genome , 1998, Microbiology and Molecular Biology Reviews.

[30]  M. Sarker,et al.  The Yersinia Yop Virulon: LcrV Is Required for Extrusion of the Translocators YopB and YopD , 1998, Journal of bacteriology.

[31]  R. Titball,et al.  Regions of Yersinia pestis V antigen that contribute to protection against plague identified by passive and active immunization , 1997, Infection and immunity.

[32]  R. Perry,et al.  Genetic organization of the yersiniabactin biosynthetic region and construction of avirulent mutants in Yersinia pestis , 1997, Infection and immunity.

[33]  E. Bottone.  Yersinia enterocolitica: the charisma continues. , 1997 .

[34]  J. Heesemann,et al.  Passive immunity to infection with Yersinia spp. mediated by anti-recombinant V antigen is dependent on polymorphism of V antigen , 1997, Infection and immunity.

[35]  R. Perry,et al.  Yersinia pestis--etiologic agent of plague , 1997, Clinical microbiology reviews.

[36]  M. Prentice,et al.  Characterization of a large chromosomal "high-pathogenicity island" in biotype 1B Yersinia enterocolitica , 1996, Journal of bacteriology.

[37]  R. Perry,et al.  YbtA, an AraC‐type regulator of the Yersinia pestis pesticin/yersiniabactin receptor , 1996, Molecular microbiology.

[38]  H. A. Jones,et al.  The hmu locus of Yersinia pestis is essential for utilization of free haemin and haem‐protein complexes as iron sources , 1996, Molecular Microbiology.

[39]  J. Heesemann,et al.  Evidence for two evolutionary lineages of highly pathogenic Yersinia species , 1995, Journal of bacteriology.

[40]  J. Lillard,et al.  Analysis of the pesticin receptor from Yersinia pestis: role in iron-deficient growth and possible regulation by its siderophore , 1995, Journal of bacteriology.

[41]  V. Motin,et al.  Passive immunity to yersiniae mediated by anti-recombinant V antigen and protein A-V antigen fusion peptide , 1994, Infection and immunity.

[42]  R. Brubaker,et al.  Association between virulence of Yersinia pestis and suppression of gamma interferon and tumor necrosis factor alpha , 1993, Infection and immunity.

[43]  M. Telepnev,et al.  The difference in the lcrV sequences between Y. pestis and Y. pseudotuberculosis and its application for characterization of Y. pseudotuberculosis strains. , 1992, Microbial pathogenesis.

[44]  R. Perry,et al.  Identification and cloning of a hemin storage locus involved in the pigmentation phenotype of Yersinia pestis , 1990, Journal of bacteriology.

[45]  R. Perry,et al.  A low-Ca2+ response operon encodes the V antigen of Yersinia pestis , 1986, Infection and immunity.

[46]  R. Germanier,et al.  Isolation and characterization of Gal E mutant Ty 21a of Salmonella typhi: a candidate strain for a live, oral typhoid vaccine. , 1975, The Journal of infectious diseases.

[47]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[48]  R. Curtiss,et al.  Kinetic and Genetic Analyses of d-Cycloserine Inhibition and Resistance in Escherichia coli , 1965, Journal of bacteriology.

[49]  G. Bertani,et al.  STUDIES ON LYSOGENESIS I , 1951, Journal of bacteriology.

[50]  R. Curtiss,et al.  Oral vaccination with different antigens from Yersinia pestis KIM delivered by live attenuated Salmonella typhimurium elicits a protective immune response against plague. , 2007, Advances in experimental medicine and biology.

[51]  B. Gunn,et al.  Induction of Host Immune Responses Using Salmonella-Vectored Vaccines , 2007 .