Effects of taurine supplementation on VDT work induced visual stress

Summary.In order to evaluate the effects of dietary taurine supplementation on visual fatigue induced by visual display terminals (VDT) work, 25 male college students aged from 20 to 24 years who were not engaged in VDT work were selected to participate in the study. Volunteers were randomly assigned to either the taurine supplementation (n=13) or the placebo supplementation control group (n=12). Before and after 12 days of taurine (3 g/day) or placebo supplementation, two identical 2.5-hr VDT work tests were performed while recording the P100, N75 and N145 latencies and P100 amplitude of pattern visual evoked potential (PVEP) and the frequency of critical flicker fusion (CFF). Following 2.5-hr of VDT work, the P100 and N75 latencies of PVEP increased (P<0.01) while the P100 amplitude decreased significantly (P<0.01). The frequency of CFF also reduced significantly (P<0.01). After 12 days of taurine supplementation, the reduction in P100 amplitude after VDT work alleviated significantly (P<0.05). The results suggest that taurine supplementation alleviates visual fatigue induced by VDT work.

[1]  D. Górny,et al.  [Effect of various amino acids on acetylcholine metabolism in brain tissue]. , 1982, Medicina.

[2]  T Iwasaki,et al.  Eye-strain and changes in accommodation of the eye and in visual evoked potential following quantified visual load. , 1988, Ergonomics.

[3]  K Yoshino,et al.  [An experimental study on the duration of a single spell of work on VDT (visual display terminal) performance]. , 1984, Sangyo igaku. Japanese journal of industrial health.

[4]  W. Zimmerman,et al.  Antioxidant activity of retinol, glutathione, and taurine in bovine photoreceptor cell membranes. , 1999, Experimental eye research.

[5]  I. Bodis-Wollner.  Visual deficits related to dopamine deficiency in experimental animals and Parkinson's disease patients , 1990, Trends in Neurosciences.

[6]  M. S. Berman,et al.  Blur‐Induced Changes in the Visual Evoked Potential , 1982, American journal of optometry and physiological optics.

[7]  J. Morán,et al.  Pharmacological identification of retinal cells releasing taurine by light stimulation , 1986, Journal of neuroscience research.

[8]  L. Ahtee,et al.  Effects of taurine, homotaurine and GABA on hypothalamic and striatal dopamine metabolism , 1992, Naunyn-Schmiedeberg's Archives of Pharmacology.

[9]  H. Tallan,et al.  Taurine: biological update. , 1986, Annual review of biochemistry.

[10]  N. Fujimoto,et al.  Visual evoked potentials in relation to visual acuity in macular disease. , 2001, Acta ophthalmologica Scandinavica.

[11]  N. Kawakami,et al.  Central nervous system effects and visual fatigue in VDT workers , 1991, International archives of occupational and environmental health.

[12]  G. Aronsson,et al.  Work Content and Eye Discomfort in VDT Work. , 1995, International journal of occupational safety and ergonomics : JOSE.

[13]  H. Spekreijse,et al.  Visual evoked potentials as indicators of the workload at visual display terminals. , 1988, Ergonomics.

[14]  H. Pasantes‐Morales,et al.  Taurine and hypotaurine inhibit light-induced lipid peroxidation and protect rod outer segment structure , 1985, Brain Research.

[15]  An analysis of VEP components in optic neuritis. , 1995, Electromyography and clinical neurophysiology.

[16]  R. S. Piha,et al.  Taurine and other free amino acids in the retina, vitreous, lens, irisciliary body, and cornea of the rat eye , 1986, Neurochemical Research.

[17]  M. Ogawa.  Feasibility of overnight urine for assessing dietary intakes of sodium, potassium, protein and sulfur amino acids in field studies. , 1986, Japanese circulation journal.

[18]  S Saito,et al.  Physiological indices of visual fatigue due to VDT operation: pupillary reflexes and accommodative responses. , 1994, Industrial health.

[19]  K. Murata,et al.  Accumulation of VDT work-related visual fatigue assessed by visual evoked potential, near point distance and critical flicker fusion. , 1996, Industrial health.

[20]  J. Lombardini.  Taurine: retinal function , 1991, Brain Research Reviews.

[21]  J. Sturman,et al.  Visual acuity loss ion rhesus monkey infants fed a taurine‐free human infant formula , 1987, Journal of neuroscience research.

[22]  V. Jousmäki,et al.  Prolonged Latencies of Pattern Reversal Visual Evoked Early Potentials in Alzheimer Disease , 1994, Alzheimer disease and associated disorders.