Evaluation of Mutual Information and Feature Selection for SARS-CoV-2 Respiratory Infection

This study aims to develop a predictive model for SARS-CoV-2 using machine-learning techniques and to explore various feature selection methods to enhance the accuracy of predictions. A precise forecast of the SARS-CoV-2 respiratory infections spread can help with efficient planning and resource allocation. The proposed model utilizes stochastic regression to capture the virus transmission’s stochastic nature, considering data uncertainties. Feature selection techniques are employed to identify the most relevant and informative features contributing to prediction accuracy. Furthermore, the study explores the use of neighbor embedding and Sammon mapping algorithms to visualize high-dimensional SARS-CoV-2 respiratory infection data in a lower-dimensional space, enabling better interpretation and understanding of the underlying patterns. The application of machine-learning techniques for predicting SARS-CoV-2 respiratory infections, the use of statistical measures in healthcare, including confirmed cases, deaths, and recoveries, and an analysis of country-wise dynamics of the pandemic using machine-learning models are used. Our analysis involves the performance of various algorithms, including neural networks (NN), decision trees (DT), random forests (RF), the Adam optimizer (AD), hyperparameters (HP), stochastic regression (SR), neighbor embedding (NE), and Sammon mapping (SM). A pre-processed and feature-extracted SARS-CoV-2 respiratory infection dataset is combined with ADHPSRNESM to form a new orchestration in the proposed model for a perfect prediction to increase the precision of accuracy. The findings of this research can contribute to public health efforts by enabling policymakers and healthcare professionals to make informed decisions based on accurate predictions, ultimately aiding in managing and controlling the SARS-CoV-2 pandemic.

[1]  M. Bhattacharya,et al.  A novel mutation-proof, next-generation vaccine to fight against upcoming SARS-CoV-2 variants and subvariants, designed through AI enabled approaches and tools, along with the machine learning based immune simulation: A vaccine breakthrough , 2023, International Journal of Biological Macromolecules.

[2]  Bakr Ahmed Taha,et al.  Next-generation nanophotonic-enabled biosensors for intelligent diagnosis of SARS-CoV-2 variants , 2023, Science of The Total Environment.

[3]  X. Le,et al.  CRISPR techniques and potential for the detection and discrimination of SARS-CoV-2 variants of concern , 2023, TrAC Trends in Analytical Chemistry.

[4]  Shannon Seney,et al.  Cross-immunity against SARS-COV-2 variants of concern in naturally infected critically ill COVID-19 patients , 2022, Heliyon.

[5]  L. Mirabella,et al.  Machine learning and predictive models: 2 years of Sars-CoV-2 pandemic in a single-center retrospective analysis , 2022, Journal of Anesthesia, Analgesia and Critical Care.

[6]  Ishan Budhiraja,et al.  A comprehensive review on variants of SARS-CoVs-2: Challenges, solutions and open issues , 2022, Computer Communications.

[7]  Son Tung Ngo,et al.  Searching for potential inhibitors of SARS-COV-2 main protease using supervised learning and perturbation calculations , 2022, Chemical Physics.

[8]  B. Sokhansanj,et al.  Predicting COVID-19 disease severity from SARS-CoV-2 spike protein sequence by mixed effects machine learning , 2022, Computers in Biology and Medicine.

[9]  Cédric R. Weber,et al.  Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain , 2022, Cell.

[10]  S. Mande,et al.  Can machines learn the mutation signatures of SARS-CoV-2 and enable viral-genotype guided predictive prognosis? , 2022, Journal of Molecular Biology.

[11]  Zeynep Banu Ozger,et al.  A new approach for determining SARS-CoV-2 epitopes using machine learning-based in silico methods , 2022, Computational Biology and Chemistry.

[12]  A. M. Fathollahi-Fard,et al.  Journal Pre-proof Supply chain disruption during the COVID-19 pandemic: Recognizing potential disruption management strategies , 2022 .

[13]  M. Gartia,et al.  Probing the mutation independent interaction of DNA probes with SARS-CoV-2 variants through a combination of surface-enhanced Raman scattering and machine learning , 2022, Biosensors and Bioelectronics.

[14]  D. Végh,et al.  Machine learning prediction of 3CLpro SARS-CoV-2 docking scores , 2022, Computational Biology and Chemistry.

[15]  B. Karimi,et al.  Sustainable and Robust Home Healthcare Logistics: A Response to the COVID-19 Pandemic , 2022, Symmetry.

[16]  K. Salama,et al.  'All In One' SARS-CoV-2 variant recognition platform: Machine learning-enabled point of care diagnostics , 2022, Biosensors and Bioelectronics: X.

[17]  Marcin J. Skwark,et al.  Early computational detection of potential high-risk SARS-CoV-2 variants , 2021, bioRxiv.

[18]  Sidi Chen,et al.  Metaviromic identification of discriminative genomic features in SARS-CoV-2 using machine learning , 2021, Patterns.

[19]  T. Chik,et al.  Machine learning application for the prediction of SARS-CoV-2 infection using blood tests and chest radiograph , 2021, Scientific Reports.

[20]  C. B. Bastos Filho,et al.  Machine learning applied in SARS-CoV-2 COVID 19 screening using clinical analysis parameters , 2021, IEEE Latin America Transactions.

[21]  Tudor I. Oprea,et al.  A machine learning platform to estimate anti-SARS-CoV-2 activities , 2021, Nature Machine Intelligence.