The Prevalence and Incidence of Diabetes in Germany.

BACKGROUND The database of the German Institute of Medical Documentation and Information makes it possible for the first time to compute statistics on diabetes for all insurees of the statutory health insurance scheme in Germany. Data from this comprehensive source are less likely to be biased by differences in the membership structures of individual insurance carriers or by the underrepresentation of persons over age 80 that is seen in most population-based studies. METHODS International Classification of Diseases (ICD)-coded diagnosis data from the inpatient and outpatient sectors were used to define persons as having diabetes. Incidences were estimated from differences in prevalence from one year to the next and the expected mortality of persons with and without diabetes. RESULTS A diabetes diagnosis was present in 6.4 million out of a total of 65.6 million insurees in 2009 and in 6.7 million out of 64.9 million insures in 2010. The corresponding age and sex standardized prevalences of diabetes were 9.7% in 2009 and 9.9% in 2010, respectively. The number of persons with type 2 diabetes was 4.6 million in 2009 and 4.7 million in 2010. The prevalence and incidence of type 2 diabetes rose steeply from age 50 to age 80. Peak incidence was at age 85, with 24 newly diagnosed cases of diabetes per 1000 person-years. CONCLUSION On the basis of these data, we estimate that 5.8 million persons with type 2 diabetes are living in Germany today. The database used in this study is a valuable complement to population-based studies for monitoring the prevalence of diabetes, particularly in persons over age 80.

[1]  G. Gallus,et al.  Age- and sex-specific prevalences of diabetes and impaired glucose regulation in 13 European cohorts. , 2003, Diabetes care.

[2]  G. Giani,et al.  Trends in Incidence Rates during 1999-2008 and Prevalence in 2008 of Childhood Type 1 Diabetes Mellitus in GERMANY – Model-Based National Estimates , 2015, PloS one.

[3]  W. Rathmann,et al.  [Prevalence and temporal trend of known diabetes mellitus: results of the German Health Interview and Examination Survey for Adults (DEGS1)]. , 2013, Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz.

[4]  R. Holle,et al.  Regional differences in the incidence of self-reported type 2 diabetes in Germany: results from five population-based studies in Germany (DIAB-CORE Consortium) , 2014, Journal of Epidemiology & Community Health.

[5]  Prevalence of Diabetes Mellitus and Quality of Care in Hesse, Germany, 1998-2004 , 2007 .

[6]  S. Wild,et al.  Diabetes in Europe: an update. , 2014, Diabetes research and clinical practice.

[7]  T. Vos,et al.  Trends in disease burden in Germany: results, implications and limitations of the Global Burden of Disease study. , 2014, Deutsches Arzteblatt international.

[8]  R. Brinks,et al.  A new relation between prevalence and incidence of a chronic disease , 2015, Mathematical medicine and biology : a journal of the IMA.

[9]  T. Wilke,et al.  Inzidenz und Prävalenz von Diabetes mellitus Typ 2 in Deutschland , 2013, Deutsche Medizinische Wochenschrift.

[10]  K. Borch-Johnsen,et al.  The Danish National Diabetes Register: trends in incidence, prevalence and mortality , 2008, Diabetologia.

[11]  I. Schubert,et al.  Fortschreibung der KoDiM-Studie: Kosten des Diabetes mellitus 2000–2009 , 2012, Deutsche Medizinische Wochenschrift.

[12]  W. Rathmann,et al.  Prevalence of undiagnosed diabetes and impaired glucose regulation in 35–59‐year‐old individuals in Southern Germany: the KORA F4 Study , 2010, Diabetic medicine : a journal of the British Diabetic Association.

[13]  R. Holle,et al.  Regional differences in the prevalence of known Type 2 diabetes mellitus in 45–74 years old individuals: Results from six population‐based studies in Germany (DIAB‐CORE Consortium) , 2012, Diabetic medicine : a journal of the British Diabetic Association.

[14]  K. Dietz,et al.  Epidemiological Perspectives on Type 1 Diabetes in Childhood and Adolescence in Germany , 2009, Diabetes Care.

[15]  A. J. Culyer Deutsches Institut Für Medizinische Dokumentation Und Information , 2014 .

[16]  W. Rathmann,et al.  Prävalenz und zeitliche Entwicklung des bekannten Diabetes mellitus , 2013, Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz.

[17]  G. Giani,et al.  Deriving age‐specific incidence from prevalence with an ordinary differential equation , 2013, Statistics in medicine.

[18]  H. Löwel,et al.  High prevalence of undiagnosed diabetes mellitus in Southern Germany: Target populations for efficient screening. The KORA survey 2000 , 2003, Diabetologia.

[19]  N. Müller,et al.  Healthcare utilization of people with Type 2 diabetes in Germany: an analysis based on health insurance data , 2015, Diabetic medicine : a journal of the British Diabetic Association.

[20]  D. Schwartz,et al.  [Incidence and prevalence of type 2 diabetes mellitus in Germany: an analysis based on 5.43 million patients]. , 2013, Deutsche medizinische Wochenschrift.