c-Myc Transforms Human Mammary Epithelial Cells through Repression of the Wnt Inhibitors DKK1 and SFRP1
暂无分享,去创建一个
Michael D. Cole | Lewis A. Chodosh | L. Chodosh | M. Cole | V. Cowling | C. D’Cruz | Victoria H. Cowling | Celina M. D'Cruz
[1] M. Hung,et al. β-Catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression , 2000 .
[2] A. Levine,et al. WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene. , 2000, Genes & development.
[3] Harold E. Varmus,et al. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome , 1982, Cell.
[4] K. Brennan,et al. Wnt Proteins in Mammary Development and Cancer , 2004, Journal of Mammary Gland Biology and Neoplasia.
[5] Mitchell D Schnall,et al. Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis. , 2002, Cancer cell.
[6] G. Evan,et al. A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. , 1995, Nucleic acids research.
[7] Robert D Cardiff,et al. Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis. , 2003, Genes & development.
[8] A. Sparks,et al. Identification of c-MYC as a target of the APC pathway. , 1998, Science.
[9] L. Penn,et al. Negative autoregulation of c‐myc transcription. , 1990, The EMBO journal.
[10] Randall T Moon,et al. A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. , 2003, Developmental cell.
[11] R. Cardiff,et al. c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations , 2001, Nature Medicine.
[12] S. Fuchs,et al. CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling. , 2006, Nature.
[13] S. Aaronson,et al. An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. , 2004, Cancer cell.
[14] S. Fuchs,et al. CRD-BP mediates stabilization of βTrCP1 and c-myc mRNA in response to β-catenin signalling , 2006, Nature.
[15] S. Baylin,et al. Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction? , 2006, Nature Reviews Cancer.
[16] Jonathan R Pollack,et al. A transcriptional response to Wnt protein in human embryonic carcinoma cells , 2002, BMC Developmental Biology.
[17] T. Kiyono,et al. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells , 1998, Nature.
[18] Hans Clevers,et al. The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. , 2002, Cell.
[19] Kathryn A. O’Donnell,et al. The c-Myc target gene network. , 2006, Seminars in cancer biology.
[20] Irina Klaman,et al. Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors. , 2004, International journal of oncology.
[21] M. Hung,et al. Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[22] G Leclercq,et al. Stable 'portrait' of breast tumors during progression: data from biology, pathology and genetics. , 2004, Endocrine-related cancer.
[23] Jean Paul Thiery,et al. Epithelial-mesenchymal transitions in development and pathologies. , 2003, Current opinion in cell biology.
[24] Christof Niehrs,et al. Kremen proteins are Dickkopf receptors that regulate Wnt/β-catenin signalling , 2002, Nature.
[25] R. Nusse,et al. Wnt signaling in disease and in development , 2005, Cell Research.
[26] L. M. Facchini,et al. Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle. , 1994, Oncogene.
[27] D. Liao,et al. c-Myc in breast cancer. , 2000, Endocrine-related cancer.
[28] T. Pramila,et al. Interaction of Frizzled Related Protein (FRP) with Wnt Ligands and the Frizzled Receptor Suggests Alternative Mechanisms for FRP Inhibition of Wnt Signaling* , 1999, The Journal of Biological Chemistry.
[29] Yoshiaki Kawano,et al. Secreted antagonists of the Wnt signalling pathway , 2003, Journal of Cell Science.
[30] L. Penn,et al. The myc oncogene: MarvelouslY Complex. , 2002, Advances in cancer research.
[31] B. Groner,et al. Targeted c‐myc gene expression in mammary glands of transgenic mice induces mammary tumours with constitutive milk protein gene transcription. , 1988, The EMBO journal.
[32] R. Assoian,et al. Anchorage-dependent Cell Cycle Progression , 1997, The Journal of cell biology.
[33] M. Mahadevappa,et al. SARPs: a family of secreted apoptosis-related proteins. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[34] Christof Niehrs,et al. Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling. , 2002, Nature.
[35] M. Cole,et al. E-cadherin repression contributes to c-Myc-induced epithelial cell transformation , 2007, Oncogene.
[36] D. Birnbaum,et al. WNT pathway and mammary carcinogenesis: Loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type , 2001, Oncogene.
[37] Hans Clevers,et al. Caught up in a Wnt storm: Wnt signaling in cancer. , 2003, Biochimica et biophysica acta.
[38] M. Cole,et al. Mechanism of transcriptional activation by the Myc oncoproteins. , 2006, Seminars in cancer biology.
[39] K. Alitalo,et al. Repression of cyclin D1: a novel function of MYC. , 1994, Molecular and cellular biology.
[40] P. Leder,et al. Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes , 1984, Cell.
[41] R. Moon,et al. Direct regulation of the Xenopus engrailed-2 promoter by the Wnt signaling pathway, and a molecular screen for Wnt-responsive genes, confirm a role for Wnt signaling during neural patterning in Xenopus , 1999, Mechanisms of Development.
[42] M. Loda,et al. Growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line. , 2002, Cancer research.
[43] Masafumi Nakamura,et al. Pin1 regulates turnover and subcellular localization of β-catenin by inhibiting its interaction with APC , 2001, Nature Cell Biology.
[44] R. Dickson,et al. Of Mice and Myc: c-Myc and Mammary Tumorigenesis , 2004, Journal of Mammary Gland Biology and Neoplasia.
[45] M. Eilers,et al. Negative regulation of the mammalian UV response by Myc through association with Miz-1. , 2002, Molecular cell.
[46] A. Børresen-Dale,et al. TP53 and breast cancer , 2003, Human mutation.
[47] Jeffrey D. Axelrod,et al. A Second Canon , 2003 .
[48] A. Bejsovec. Wnt Pathway Activation New Relations and Locations , 2005, Cell.
[49] A. Levine,et al. WISP-1 is a Wnt-1- and β-catenin-responsive oncogene , 2000, Genes & Development.
[50] B. Trock,et al. C-myc amplification in breast cancer: a meta-analysis of its occurrence and prognostic relevance , 2000, British Journal of Cancer.
[51] H. Varmus,et al. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice , 1988, Cell.
[52] R. Palmiter,et al. Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice. , 1995, Cancer research.
[53] W. Hahn,et al. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. , 2001, Genes & development.
[54] K. Kinzler,et al. Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma , 1997, Science.
[55] R. Nusse,et al. The Wnt signaling pathway in development and disease. , 2004, Annual review of cell and developmental biology.
[56] C. Conti,et al. Lack of Cyclin-Dependent Kinase 4 Inhibits c-myc Tumorigenic Activities in Epithelial Tissues , 2004, Molecular and Cellular Biology.
[57] C. Niehrs,et al. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction , 1998, Nature.