Far-infrared signature of animal tissues characterized by terahertz time-domain spectroscopy

We present terahertz time-domain spectroscopy characterization of various animal tissues obtained from pork and rats. As the sensitivity of terahertz radiation to polar molecules of water is very high, biological tissues with high level of hydration show strong absorption at terahertz frequencies. The experimental data indicate that skin, fat and lean pork tissues have different frequency-dependent response to terahertz radiation due to the variation in water content. The same type tissue from different animals, however, is observed to show very similar water absorption.

[1]  Bryan Edward Cole,et al.  Terahertz imaging and spectroscopy of human skin in vivo , 2001, SPIE LASE.

[2]  Jun-ichi Nishizawa,et al.  THz imaging of nucleobases and cancerous tissue using a GaP THz-wave generator , 2005 .

[3]  E. Linfield,et al.  Terahertz pulse imaging of ex vivo basal cell carcinoma. , 2003, The Journal of investigative dermatology.

[4]  A. Azad,et al.  Far-infrared optical and dielectric response of ZnS measured by terahertz time-domain spectroscopy , 2005 .

[5]  Hanspeter Helm,et al.  Far-infrared vibrational spectra of all-trans, 9-cis and 13-cis retinal measured by THz time-domain spectroscopy , 2000 .

[6]  Jiangquan Zhang,et al.  Waveguide terahertz time-domain spectroscopy of nanometer water layers. , 2004, Optics letters.

[7]  E. Linfield,et al.  Terahertz pulse imaging in reflection geometry of human skin cancer and skin tissue. , 2002, Physics in medicine and biology.

[8]  E. Pickwell‐MacPherson,et al.  Simulation of Terahertz Pulse Propagation in Biological Systems , 2004 .

[9]  A. Bosserhoff,et al.  Label-Free Probing of the Binding State of DNA by Time-Domain Terahertz Sensing , 2000 .

[10]  Xicheng Zhang,et al.  Materials for terahertz science and technology , 2002, Nature materials.

[11]  E. Heilweil,et al.  Pulsed terahertz spectroscopy of DNA, bovine serum albumin and collagen between 0.1 and 2.0 THz , 2000 .

[12]  K. Siebert,et al.  Terahertz dark-field imaging of biomedical tissue. , 2001, Optics express.

[13]  G. Cho,et al.  Time-domain transillumination of biological tissues with terahertz pulses. , 2000, Optics letters.

[14]  Andrew G. Glen,et al.  APPL , 2001 .