Recognition and Clinical Diagnosis of Cervical Cancer Cells Based on our Improved Lightweight Deep Network for Pathological Image

Accurate recognition of cervical cancer cells is of great significance to clinical diagnosis, but these existing algorithms are designed by low-level manual feature, and their performance improvements are limited an improved algorithm based on residual neural network is proposed to improve the accuracy of diagnosis. Firstly, momentum parameters are introduced into the training model; secondly, by changing the number of training samples, the recognition rate of the algorithm can be improved. Therefore, aiming at the task of object recognition under resource constrained condition, we optimize the design method of the network structure such as convolution operation, model parameter compression and enhancement of feature expression depth, and design and implement the lightweight network model structure for embedded platform. Our proposed deep network model can reduce the parameters of the model and the resources needed for operation under the condition of guaranteeing the precision. The experimental results show that the lightweight deep model has better performance than that of the existing comparison models, and it can achieve the model accuracy of 94.1% under the condition that the model with fewer parameters on cervical cells data set.

[1]  Yiming Liu,et al.  Automatic Segmentation of Cervical Nuclei Based on Deep Learning and a Conditional Random Field , 2018, IEEE Access.

[2]  Kwong-Sak Leung,et al.  An expert system for the detection of cervical cancer cells using knowledge-based image analyzer , 1996, Artif. Intell. Medicine.

[3]  Yuichiro Miyamoto,et al.  Application of deep learning to the classification of images from colposcopy , 2018, Oncology letters.

[4]  Yue Wang,et al.  Optimizing the cervix cytological examination based on deep learning and dynamic shape modeling , 2017, Neurocomputing.

[5]  C. Chou,et al.  EGF upregulates Na+/H+ exchanger NHE1 by post‐translational regulation that is important for cervical cancer cell invasiveness , 2008, Journal of cellular physiology.

[6]  Bai Ying Lei,et al.  Accurate Segmentation of Cervical Cytoplasm and Nuclei Based on Multiscale Convolutional Network and Graph Partitioning , 2015, IEEE Transactions on Biomedical Engineering.

[7]  Yu Zhang,et al.  Metal artifact reduction on cervical CT images by deep residual learning , 2018, BioMedical Engineering OnLine.

[8]  N.G. Nguyen,et al.  Some new color features and their application to cervical cell classification , 1983, Pattern Recognit..

[9]  L. Miroslaw,et al.  Towards rapid cervical cancer diagnosis: automated detection and classification of pathologic cells in phase-contrast images , 2006, International Journal of Gynecologic Cancer.

[10]  J. Bacus Cervical cell recognition and morphometric grading by image analysis , 1995, Journal of cellular biochemistry. Supplement.

[11]  Linghong Zhou,et al.  Deep convolutional neural network with transfer learning for rectum toxicity prediction in cervical cancer radiotherapy: a feasibility study , 2017, Physics in medicine and biology.

[12]  Babak Sokouti,et al.  A framework for diagnosing cervical cancer disease based on feedforward MLP neural network and ThinPrep histopathological cell image features , 2012, Neural Computing and Applications.

[13]  Babak Sokouti,et al.  A Pilot Study on Image Analysis Techniques for Extracting Early Uterine Cervix Cancer Cell Features , 2012, Journal of Medical Systems.

[14]  Hongsheng Yin,et al.  Deep Semantic Segmentation of Kidney and Space-Occupying Lesion Area Based on SCNN and ResNet Models Combined with SIFT-Flow Algorithm , 2018, Journal of Medical Systems.

[15]  Ronald M. Summers,et al.  DeepPap: Deep Convolutional Networks for Cervical Cell Classification , 2017, IEEE Journal of Biomedical and Health Informatics.

[16]  Hady Ahmady Phoulady,et al.  A New Cervical Cytology Dataset for Nucleus Detection and Image Classification (Cervix93) and Methods for Cervical Nucleus Detection , 2018, ArXiv.

[17]  Xiangyu Zhang,et al.  ShuffleNet V2: Practical Guidelines for Efficient CNN Architecture Design , 2018, ECCV.

[18]  Sameer Antani,et al.  Deep Learning Nuclei Detection in Digitized Histology Images by Superpixels , 2018, Journal of pathology informatics.

[19]  Xiaonan Luo,et al.  Learning a Wavelet-like Auto-Encoder to Accelerate Deep Neural Networks , 2017, AAAI.

[20]  Malay Kumar Kundu,et al.  Pap smear image classification using convolutional neural network , 2016, ICVGIP '16.

[21]  Yue Wu,et al.  Robust Alzheimer Disease Classification Based on Feature Integration Fusion Model for Magnetic , 2017 .

[22]  Young H. Cho,et al.  Deep network packet filter design for reconfigurable devices , 2008, TECS.

[23]  Nguyen Phuoc Long,et al.  Systematic assessment of cervical cancer initiation and progression uncovers genetic panels for deep learning-based early diagnosis and proposes novel diagnostic and prognostic biomarkers , 2017, Oncotarget.

[24]  Ronald M. Summers,et al.  Combining fully convolutional networks and graph-based approach for automated segmentation of cervical cell nuclei , 2017, 2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017).

[25]  Chih-Jen Tseng,et al.  Application of machine learning to predict the recurrence-proneness for cervical cancer , 2013, Neural Computing and Applications.

[26]  Yeongjae Cheon,et al.  PVANET: Deep but Lightweight Neural Networks for Real-time Object Detection , 2016, ArXiv.

[27]  G. Valdes,et al.  Comment on ‘Deep convolutional neural network with transfer learning for rectum toxicity prediction in cervical cancer radiotherapy: a feasibility study’ , 2018, Physics in medicine and biology.

[28]  Alan D. George,et al.  RapidIO for radar processing in advanced space systems , 2007, TECS.

[29]  Shengzhe Wang,et al.  Bayesian Framework with Non-local and Low-rank Constraint for Image Reconstruction , 2017 .

[30]  Qiang Liu,et al.  Complete three-phase detection framework for identifying abnormal cervical cells , 2017, IET Image Process..