Insights into the Genetic Architecture of Diabetic Nephropathy

[1]  M. Rocco,et al.  Association of APOL1 variants with mild kidney disease in first-degree relatives of African American patients with non-diabetic end stage renal disease , 2012, Kidney international.

[2]  C. Langefeld,et al.  Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans. , 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[3]  Deyu Zhao,et al.  Association between genetic polymorphism of the angiotensin-converting enzyme and diabetic nephropathy: a meta-analysis comprising 26,580 subjects , 2012, Journal of the renin-angiotensin-aldosterone system : JRAAS.

[4]  T. Trikalinos,et al.  Meta-analysis of genome-wide linkage scans for renal function traits. , 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[5]  G. Genovese,et al.  Population-based risk assessment of APOL1 on renal disease. , 2011, Journal of the American Society of Nephrology : JASN.

[6]  Giulio Genovese,et al.  APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy. , 2011, Journal of the American Society of Nephrology : JASN.

[7]  A. Köttgen,et al.  The MYH9/APOL1 region and chronic kidney disease in European-Americans. , 2011, Human molecular genetics.

[8]  Nicholette D. Palmer,et al.  Differential Effects of MYH9 and APOL1 Risk Variants on FRMD3 Association with Diabetic ESRD in African Americans , 2011, PLoS genetics.

[9]  T. Ahluwalia,et al.  Common variants in CNDP1 and CNDP2, and risk of nephropathy in type 2 diabetes , 2011, Diabetologia.

[10]  Jasmin Divers,et al.  A genome-wide association study for diabetic nephropathy genes in African Americans. , 2011, Kidney international.

[11]  B. Freedman,et al.  Effects of race on albuminuria and risk of cardiovascular and kidney disease , 2011, Expert review of cardiovascular therapy.

[12]  C. Sapienza,et al.  DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy , 2011, Epigenetics.

[13]  S. Antonio.  Genomewide Linkage Scan for Diabetic Renal Failure and Albuminuria: The FIND Study , 2011 .

[14]  J. Herman,et al.  Beyond genetics: epigenetic code in chronic kidney disease. , 2011, Kidney international.

[15]  O. Dekkers,et al.  Genetic associations in diabetic nephropathy: a meta-analysis , 2010, Diabetologia.

[16]  C. Langefeld,et al.  The acetyl-coenzyme A carboxylase beta (ACACB) gene is associated with nephropathy in Chinese patients with type 2 diabetes. , 2010, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[17]  C. Winkler,et al.  The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans. , 2010, Journal of the American Society of Nephrology : JASN.

[18]  Xilin Yang,et al.  Genetic variants of the protein kinase C-beta 1 gene and development of end-stage renal disease in patients with type 2 diabetes. , 2010, JAMA.

[19]  C. Winkler,et al.  Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans , 2010, Science.

[20]  S. Rosset,et al.  Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene , 2010, Human Genetics.

[21]  M. King,et al.  Genetic Heterogeneity in Human Disease , 2010, Cell.

[22]  T. Hansen,et al.  A Single Nucleotide Polymorphism within the Acetyl-Coenzyme A Carboxylase Beta Gene Is Associated with Proteinuria in Patients with Type 2 Diabetes , 2010, PLoS genetics.

[23]  Donald W. Bowden,et al.  Association of Trypanolytic ApoL 1 Variants with Kidney Disease in African Americans , 2010 .

[24]  A. Krolewski,et al.  In patients with type 1 diabetes and new-onset microalbuminuria the development of advanced chronic kidney disease may not require progression to proteinuria. , 2010, Kidney international.

[25]  鮫島 浩,et al.  Population-based study からみた神経予後不良因子の検討 , 2009 .

[26]  Judy H. Cho,et al.  Finding the missing heritability of complex diseases , 2009, Nature.

[27]  Stephen S. Rich,et al.  Confirmation of Genetic Associations at ELMO1 in the GoKinD Collection Supports Its Role as a Susceptibility Gene in Diabetic Nephropathy , 2009, Diabetes.

[28]  Thomas Meitinger,et al.  Genome-wide linkage analysis of serum creatinine in three isolated European populations. , 2009, Kidney international.

[29]  P. Donnelly,et al.  A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies , 2009, PLoS genetics.

[30]  F. Collins,et al.  The HapMap and genome-wide association studies in diagnosis and therapy. , 2009, Annual review of medicine.

[31]  C. Langefeld,et al.  Variants in Intron 13 of the ELMO1 Gene are Associated with Diabetic Nephropathy in African Americans , 2009, Annals of human genetics.

[32]  Stephen S. Rich,et al.  Genome-Wide Association Scan for Diabetic Nephropathy Susceptibility Genes in Type 1 Diabetes , 2009, Diabetes.

[33]  J. Tuomilehto,et al.  Association of genetic variants at 3q22 with nephropathy in patients with type 1 diabetes mellitus. , 2009, American journal of human genetics.

[34]  D. Vlahov,et al.  MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis , 2008, Nature Genetics.

[35]  D. Reich,et al.  MYH9 is associated with nondiabetic end-stage renal disease in African Americans , 2008, Nature Genetics.

[36]  Jennifer K. Sun,et al.  Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications , 2008, Proceedings of the National Academy of Sciences.

[37]  Francis S Collins,et al.  A HapMap harvest of insights into the genetics of common disease. , 2008, The Journal of clinical investigation.

[38]  R. Elston,et al.  Genome-Wide Scan for Estimated Glomerular Filtration Rate in Multi-Ethnic Diabetic Populations , 2008, Diabetes.

[39]  Zhaohui S. Qin,et al.  A second generation human haplotype map of over 3.1 million SNPs , 2007, Nature.

[40]  T. Hansen,et al.  Polymorphisms in the 3′ UTR in the neurocalcin δ gene affect mRNA stability, and confer susceptibility to diabetic nephropathy , 2007, Human Genetics.

[41]  T. Hayashi,et al.  Genetic variations associated with diabetic nephropathy and type II diabetes in a Japanese population. , 2007, Kidney international. Supplement.

[42]  R. Elston,et al.  Genome-Wide Scans for Diabetic Nephropathy and Albuminuria in Multiethnic Populations , 2007, Diabetes.

[43]  C. Langefeld,et al.  A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans. , 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[44]  John V Pearson,et al.  Identification of PVT1 as a Candidate Gene for End-Stage Renal Disease in Type 2 Diabetes Using a Pooling-Based Genome-Wide Single Nucleotide Polymorphism Association Study , 2007, Diabetes.

[45]  R. Jirtle,et al.  Environmental epigenomics and disease susceptibility , 2007, Nature Reviews Genetics.

[46]  J. Tuomilehto,et al.  Genome-wide scan for type 1 diabetic nephropathy in the Finnish population reveals suggestive linkage to a single locus on chromosome 3q. , 2007, Kidney international.

[47]  S. Heath,et al.  Analysis of 14 Candidate Genes for Diabetic Nephropathy on Chromosome 3q in European Populations , 2006, Diabetes.

[48]  E. Zintzaras,et al.  Identification of chromosomal regions linked to premature myocardial infarction: a meta-analysis of whole-genome searches , 2006, Journal of Human Genetics.

[49]  J. Ioannidis,et al.  Heterogeneity-based genome search meta-analysis for preeclampsia , 2006, Human Genetics.

[50]  L. Peltonen,et al.  A heterogeneity-based genome search meta-analysis for autism-spectrum disorders , 2006, Molecular Psychiatry.

[51]  Gudmundur A. Thorisson,et al.  The International HapMap Project Web site. , 2005, Genome research.

[52]  B. Freedman,et al.  Population-Based Screening for Family History of End-Stage Renal Disease among Incident Dialysis Patients , 2005, American Journal of Nephrology.

[53]  John P. A. Ioannidis,et al.  HEGESMA: genome search meta-analysis and heterogeneity testing , 2005, Bioinform..

[54]  H. Hammes,et al.  Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1. , 2005, Diabetes.

[55]  Yongmei Liu,et al.  T-786C polymorphism of the endothelial nitric oxide synthase gene is associated with albuminuria in the diabetes heart study. , 2005, Journal of the American Society of Nephrology : JASN.

[56]  Yusuke Nakamura,et al.  Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy. , 2005, Diabetes.

[57]  John P A Ioannidis,et al.  Heterogeneity testing in meta‐analysis of genome searches , 2005, Genetic epidemiology.

[58]  R. Elston,et al.  The Family Investigation of Nephropathy and Diabetes (FIND): design and methods. , 2005, Journal of diabetes and its complications.

[59]  Scott M. Williams,et al.  A high-density admixture map for disease gene discovery in african americans. , 2004, American journal of human genetics.

[60]  A. Krolewski,et al.  Familial factors determine the development of diabetic nephropathy in patients with IDDM , 1996, Diabetologia.

[61]  M. F. Saad,et al.  Familial predisposition to renal disease in two generations of Pima Indians with Type 2 (non-insulin-dependent) diabetes mellitus , 1990, Diabetologia.

[62]  R. G. Nelson,et al.  Incidence of end-stage renal disease in Type 2 (non-insulin-dependent) diabetes mellitus in pima indians , 1988, Diabetologia.

[63]  Ying Wang,et al.  Association of ecNOS gene polymorphisms with end stage renal diseases , 2004, Molecular and Cellular Biochemistry.

[64]  L. Sechi,et al.  Regression of microalbuminuria in type 1 diabetes. , 2003, The New England journal of medicine.

[65]  R. Hanson,et al.  Gene for susceptibility to diabetic nephropathy in type 2 diabetes maps to 18q22.3-23. , 2002, Kidney international.

[66]  K. Tokunaga,et al.  Association of eNOS Glu298Asp Polymorphism With End-Stage Renal Disease , 2002, Hypertension.

[67]  F. Port,et al.  Risk factors for proteinuria in a large, multiracial, southeast Asian population. , 2002, Journal of the American Society of Nephrology : JASN.

[68]  R. Myers,et al.  Candidate-gene approaches for studying complex genetic traits: practical considerations , 2002, Nature Reviews Genetics.

[69]  C. Langefeld,et al.  Prevalence of Nephropathy in Black Patients with Type 2 Diabetes mellitus , 2002, American Journal of Nephrology.

[70]  K. Tokunaga,et al.  Association of eNOS Glu 298 Asp Polymorphism With End-Stage Renal Disease , 2002 .

[71]  S. Kikuchi,et al.  Association of a missense Glu298Asp mutation of the endothelial nitric oxide synthase gene with end stage renal disease. , 2000, Clinical chemistry.

[72]  L. Groop,et al.  Heritability of albumin excretion rate in families of patients with Type II diabetes , 1999, Diabetologia.

[73]  J. Lanchbury,et al.  Meta‐analysis of genome searches , 1999, Annals of human genetics.

[74]  J. Gross,et al.  Familial clustering of diabetic nephropathy in Brazilian type 2 diabetic patients. , 1999, Diabetes.

[75]  Ambady Ramachandran,et al.  Familial aggregation of diabetic kidney disease in Type 2 diabetes in south India. , 1999, Diabetes research and clinical practice.

[76]  P. Parfrey,et al.  Higher risk for renal failure in first-degree relatives of white patients with end-stage renal disease: a population-based study. , 1998, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[77]  R. Hanson,et al.  Sib-pair linkage analysis for susceptibility genes for microvascular complications among Pima Indians with type 2 diabetes. Pima Diabetes Genes Group. , 1998, Diabetes.

[78]  B. Freedman,et al.  Family history of end-stage renal disease among incident dialysis patients. , 1997, Journal of the American Society of Nephrology : JASN.

[79]  N Risch,et al.  The Future of Genetic Studies of Complex Human Diseases , 1996, Science.

[80]  B. Freedman,et al.  Familial predisposition to nephropathy in African-Americans with non-insulin-dependent diabetes mellitus. , 1995, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[81]  B. Freedman,et al.  Familial risk, age at onset, and cause of end-stage renal disease in white Americans. , 1995, Journal of the American Society of Nephrology : JASN.

[82]  B. Freedman,et al.  The familial risk of end-stage renal disease in African Americans. , 1993, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[83]  E. Seaquist,et al.  Familial clustering of diabetic kidney disease. Evidence for genetic susceptibility to diabetic nephropathy. , 1989, The New England journal of medicine.