Artificial Endocrine System: a New Paradigm of Knowledge Discovery

We propose an artificial endocrine system (AES) for extracting the knowledge from database so that effective and reliable decision rules can be constructed. The proposed AES mimics the functionality of biological endocrine system (BES) to some extent. A mathematical model is proposed for expressive representation of endocrine system as well as for homeostasis. Further, different aspects of our proposed "Artificial endocrine system for knowledge discovery" (AESKD) have been compared with state of art classifiers e.g., support vector machine, neural network, radial basis function (RBF) network and K-NN for some bench mark datasets.

[1]  David B. Fogel,et al.  Evolutionary Computation: The Fossil Record , 1998 .

[2]  D. E. Goldberg,et al.  Genetic Algorithm in Search , 1989 .

[3]  Zbigniew Michalewicz,et al.  Evolutionary Computation 2 : Advanced Algorithms and Operators , 2000 .

[4]  Yi Han,et al.  Overview of Artificial Neural Networks , 2009, Artificial Neural Networks.

[5]  Hirokazu Ihara,et al.  Autonomous Decentralized Computer Control Systems , 1984, Computer.

[6]  Mikhail S. Gelfand,et al.  Prediction of Function in DNA Sequence , 1995, J. Comput. Biol..

[7]  K. Deb,et al.  Reliable classification of two-class cancer data using evolutionary algorithms. , 2003, Bio Systems.

[8]  Victor L. Winter,et al.  High Integrity Software , 2001 .

[9]  Peter J. Bentley,et al.  On growth, form and computers , 2003 .

[10]  R. Santen,et al.  Episodic luteinizing hormone secretion in man. Pulse analysis, clinical interpretation, physiologic mechanisms. , 1973, The Journal of clinical investigation.

[11]  Diane Gershon,et al.  Microarray technology: An array of opportunities , 2002, Nature.

[12]  Dipankar Dasgupta,et al.  Immunological Computation: Theory and Applications , 2008 .

[13]  E. Knobil,et al.  The role of the central nervous system in the control of ovarian function in higher primates. , 1982, Annual review of physiology.

[14]  E. Knobil,et al.  The neuroendocrine control of the menstrual cycle. , 1980, Recent progress in hormone research.

[15]  R. J. Bogumil,et al.  Mathematical studies of the human menstrual cycle. II. Simulation performance of a model of the human menstrual cycle. , 1972, The Journal of clinical endocrinology and metabolism.

[16]  J. Mesirov,et al.  Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. , 1999, Science.

[17]  Paul Workman,et al.  Analysis of tumour gene expression following chemotherapeutic treatment of patients with bowel cancer , 1999, Nature Genetics.

[18]  M. Waterman Mathematical Methods for DNA Sequences , 1989 .

[19]  David E. Goldberg,et al.  Genetic Algorithms in Search Optimization and Machine Learning , 1988 .

[20]  R. J. Bogumil,et al.  Mathematical studies of the human menstrual cycle. I. Formulation of a mathematical model. , 1972, The Journal of clinical endocrinology and metabolism.

[21]  J. Hall Neuroendocrine Control of the Menstrual Cycle , 2019, Yen and Jaffe's Reproductive Endocrinology.

[22]  Lei Wang,et al.  Recent advances in the artificial endocrine system , 2011, Journal of Zhejiang University SCIENCE C.

[23]  L. Danziger,et al.  Mathematical models of endocrine systems , 1957 .

[24]  Jonathan Timmis,et al.  Artificial Homeostatic System: A Novel Approach , 2005, ECAL.

[25]  Hirokazu Ihara,et al.  Autonomous decentralized control and its application to the rapid transit system , 1984 .

[26]  Simon Haykin,et al.  Neural Networks: A Comprehensive Foundation , 1998 .

[27]  F. Glover,et al.  Handbook of Metaheuristics , 2019, International Series in Operations Research & Management Science.

[28]  U. Alon,et al.  Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[29]  Liu Bingzheng,et al.  A mathematical model of the regulation system of the secretion of glucocorticoids , 1990 .

[30]  Leandro Nunes de Castro,et al.  Recent Developments In Biologically Inspired Computing , 2004 .

[31]  Jon Timmis,et al.  Timidity: A Useful Mechanism for Robot Control? , 2003 .

[32]  Jon Timmis,et al.  Once More Unto the Breach: Towards Artificial Homeostasis? , 2005 .

[33]  R. Doolittle Molecular evolution: computer analysis of protein and nucleic acid sequences. , 1990, Methods in enzymology.

[34]  Kinji Mori Autonomous decentralized systems technologies and their application to train transport operation system , 2001 .

[35]  E. Snyder,et al.  Identification of protein coding regions in genomic DNA. , 1995, Journal of molecular biology.

[36]  L.N. de Castro,et al.  An artificial immune network for multimodal function optimization , 2002, Proceedings of the 2002 Congress on Evolutionary Computation. CEC'02 (Cat. No.02TH8600).

[37]  D. Dasgupta Artificial Immune Systems and Their Applications , 1998, Springer Berlin Heidelberg.