Late seroconversion of acute schistosomiasis.

We read with great interest the article by Martinez‐Calle and colleagues1 and, being involved in ongoing research strictly related to this topic, we would like to bring some additional comments to the readers' attention. We agree that diagnosis of acute schistosomiasis is not straightforward at first presentation, especially in paucisymptomatic cases, and the authors should be congratulated for their obstinacy in seeking diagnosis in this challenging case.2–3 In a case series of patients presenting with fever, diagnosis of schistosomiasis could not be established at first contact in about one third of the cases,4 even when using a combination of parasite examination and two different serological tests [enzyme linked immunosorbent assay (ELISA) and indirect hemagglutination (IHA)]. It must be …

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[10]  R. Speare,et al.  Rectal snips in the diagnosis of hepatosplenic schistosomiasis. , 1988, Transactions of the Royal Society of Tropical Medicine and Hygiene.