The AD1 and AD2 Transactivation Domains of E2A Are Essential for the Antiapoptotic Activity of the Chimeric Oncoprotein E2A-HLF
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A. Look | T. Inaba | T. Inukai | S. Ikushima
[1] A T Look,et al. Oncogenic transcription factors in the human acute leukemias. , 1997, Science.
[2] J. Darnell. STATs and gene regulation. , 1997, Science.
[3] Kevin S. Smith,et al. Chimeric oncoprotein E2a-Pbx1 induces apoptosis of hematopoietic cells by a p53-independent mechanism that is suppressed by Bcl-2 , 1997, Oncogene.
[4] J L Cleveland,et al. Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[5] A. Look,et al. Cell transformation mediated by homodimeric E2A-HLF transcription factors , 1997, Molecular and cellular biology.
[6] A. Feeney,et al. Both E12 and E47 allow commitment to the B cell lineage. , 1997, Immunity.
[7] M. Cleary,et al. The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis , 1997, Molecular and cellular biology.
[8] H. Horvitz,et al. Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2 , 1996, Nature.
[9] A. Look,et al. Reversal of apoptosis by the leukaemia-associated E2A–HLF chimaeric transcription factor , 1996, Nature.
[10] S. Korsmeyer,et al. Molecular thanatopsis: a discourse on the BCL2 family and cell death. , 1996, Blood.
[11] M. Cleary,et al. The proto-oncogene HLF and the related basic leucine zipper protein TEF display highly similar DNA-binding and transcriptional regulatory properties. , 1996, Blood.
[12] Q. Lu,et al. Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex , 1996, Molecular and cellular biology.
[13] S. Hunger,et al. Chromosomal translocations involving the E2A gene in acute lymphoblastic leukemia: clinical features and molecular pathogenesis. , 1996, Blood.
[14] Q. Lu,et al. DNA-binding by oncoprotein E2a-Pbx1 is important for blocking differentiation but dispensable for fibroblast transformation. , 1996, Oncogene.
[15] P. Jennings,et al. The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells , 1996, Molecular and cellular biology.
[16] C. Murre,et al. The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[17] T. Kadesch,et al. B-cell-specific DNA binding by an E47 homodimer , 1995, Molecular and cellular biology.
[18] J. Cleveland,et al. c-Myc and apoptosis. , 1995, Biochimica et biophysica acta.
[19] C. Murre,et al. Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2 , 1995, Mechanisms of Development.
[20] T. Inaba,et al. E2A-HLF-mediated cell transformation requires both the trans-activation domains of E2A and the leucine zipper dimerization domain of HLF , 1995, Molecular and cellular biology.
[21] G. Lyons,et al. Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. , 1995, Development.
[22] M. Cleary,et al. Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins. , 1995, Genes & development.
[23] C. Thompson,et al. Apoptosis in the pathogenesis and treatment of disease , 1995, Science.
[24] S. Orkin,et al. Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL , 1995, Nature.
[25] Ian Krop,et al. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements , 1994, Cell.
[26] H. Weintraub,et al. The helix-loop-helix gene E2A is required for B cell formation , 1994, Cell.
[27] D. LeBrun,et al. Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable , 1994, Molecular and cellular biology.
[28] T. Rabbitts,et al. Chromosomal translocations in human cancer , 1994, Nature.
[29] R. Pepperkok,et al. Regulation of G1 progression by E2A and Id helix‐loop‐helix proteins. , 1994, The EMBO journal.
[30] J R Matthews,et al. Structure and function of helix-loop-helix proteins. , 1994, Biochimica et biophysica acta.
[31] F. Lee,et al. The E2A and tal-1 helix-loop-helix proteins associate in vivo and are modulated by Id proteins during interleukin 6-induced myeloid differentiation. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[32] H. Hsu,et al. Positive and negative transcriptional control by the TAL1 helix-loop-helix protein. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[33] M. Cleary,et al. Two types of genomic rearrangements create alternative E2A-HLF fusion proteins in t(17;19)-ALL. , 1994, Blood.
[34] T. Inaba,et al. DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein , 1994, Molecular and cellular biology.
[35] M. Cleary,et al. Bcl2 inhibits apoptosis associated with terminal differentiation of HL-60 myeloid leukemia cells. , 1994, Blood.
[36] David J. Anderson,et al. Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons , 1993, Cell.
[37] David P. LeBrun,et al. Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice , 1993, Cell.
[38] B. Spiegelman,et al. ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation , 1993, Molecular and cellular biology.
[39] R. Baler,et al. Synergistic activation of transcription is mediated by the N-terminal domain of Drosophila fushi tarazu homeoprotein and can occur without DNA binding by the protein , 1993, Molecular and cellular biology.
[40] C. Murre,et al. A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells , 1993, Molecular and cellular biology.
[41] M. Cleary,et al. Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia. , 1992, Genes & development.
[42] S. Korsmeyer. Bcl-2 initiates a new category of oncogenes: regulators of cell death. , 1992, Blood.
[43] S. Raimondi,et al. Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia. , 1992, Science.
[44] C. Ingles,et al. Homeodomain-independent activity of the fushi tarazu polypeptide in Drosophila embryos , 1992, Nature.
[45] Gerard I. Evan,et al. Induction of apoptosis in fibroblasts by c-myc protein , 1992, Cell.
[46] J. Cleveland,et al. Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. , 1991, Oncogene.
[47] L. Swanson,et al. TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins. , 1991, Genes & development.
[48] E. Olson,et al. Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding , 1991, Molecular and cellular biology.
[49] H. Hsu,et al. Enhancer-binding activity of the tal-1 oncoprotein in association with the E47/E12 helix-loop-helix proteins , 1991, Molecular and cellular biology.
[50] S. Korsmeyer,et al. Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. , 1990, Journal of immunology.
[51] Harold Weintraub,et al. The protein Id: A negative regulator of helix-loop-helix DNA binding proteins , 1990, Cell.
[52] D. Lockshon,et al. MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer , 1989, Cell.
[53] Y. Jan,et al. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence , 1989, Cell.
[54] David Baltimore,et al. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins , 1989, Cell.
[55] David L. Vaux,et al. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells , 1988, Nature.
[56] M. Rosenfeld,et al. Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain , 1988, Cell.
[57] A. W. Harris,et al. The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice , 1986, Cell.
[58] J. Sklar,et al. Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[59] J. McCubrey,et al. Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[60] C. Croce,et al. The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. , 1985, Science.
[61] S. Korsmeyer,et al. Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around Jh on chromosome 14 and near a transcriptional unit on 18 , 1985, Cell.