Improvement of Hypoxia–Ischemia-Induced White Matter Injury in Immature Rat Brain by Ethyl Pyruvate

[1]  Lei Mao,et al.  Erratum to “Beneficial Effects of Ethyl Pyruvate through Inhibiting High Mobility Group Box 1 Expression and TLR4/NF-κB Pathway after Traumatic Brain Injury in the Rat” , 2012, Mediators of Inflammation.

[2]  E. Ling,et al.  Iron and Iron Regulatory Proteins in Amoeboid Microglial Cells Are Linked to Oligodendrocyte Death in Hypoxic Neonatal Rat Periventricular White Matter through Production of Proinflammatory Cytokines and Reactive Oxygen/Nitrogen Species , 2011, The Journal of Neuroscience.

[3]  X. Liu,et al.  Quercetin protects oligodendrocyte precursor cells from oxygen/glucose deprivation injury in vitro via the activation of the PI3K/Akt signaling pathway , 2011, Brain Research Bulletin.

[4]  Yoko Sato,et al.  Hypoxia–ischemia induces hypo-phosphorylation of collapsin response mediator protein 2 in a neonatal rat model of periventricular leukomalacia , 2011, Brain Research.

[5]  E. Ling,et al.  Expression of N‐methyl D‐aspartate receptor subunits in amoeboid microglia mediates production of nitric oxide via NF‐κB signaling pathway and oligodendrocyte cell death in hypoxic postnatal rats , 2011, Glia.

[6]  J. Alberch,et al.  Bax and Calpain Mediate Excitotoxic Oligodendrocyte Death Induced by Activation of Both AMPA and Kainate Receptors , 2011, The Journal of Neuroscience.

[7]  E. Ling,et al.  Microglia‐Derived Macrophage Colony Stimulating Factor Promotes Generation of Proinflammatory Cytokines by Astrocytes in the Periventricular White Matter in the Hypoxic Neonatal Brain , 2010, Brain pathology.

[8]  Changkai Sun,et al.  Simvastatin attenuates hypomyelination induced by hypoxia–ischemia in neonatal rats , 2010, Neurological research.

[9]  Jae-Sun Choi,et al.  Ethyl pyruvate has a neuroprotective effect through activation of extracellular signal-regulated kinase in Parkinson's disease model. , 2010, Biochemical and biophysical research communications.

[10]  Jun Chen,et al.  Ethyl pyruvate protects against hypoxic-ischemic brain injury via anti-cell death and anti-inflammatory mechanisms , 2010, Neurobiology of Disease.

[11]  P. Cheung,et al.  Long-term cognitive impairment and myelination deficiency in a rat model of perinatal hypoxic-ischemic brain injury , 2009, Brain Research.

[12]  E. Mazzon,et al.  BENEFICIAL EFFECTS OF ETHYL PYRUVATE IN A MOUSE MODEL OF SPINAL CORD INJURY , 2009, Shock.

[13]  L. Xiong,et al.  Ethyl Pyruvate Attenuates Spinal Cord Ischemic Injury with a Wide Therapeutic Window through Inhibiting High-mobility Group Box 1 Release in Rabbits , 2009, Anesthesiology.

[14]  E. Ling,et al.  Periventricular white matter damage in the hypoxic neonatal brain: Role of microglial cells , 2009, Progress in Neurobiology.

[15]  Haichao Wang,et al.  Ethyl pyruvate improves survival in awake hemorrhage , 2009, Journal of Molecular Medicine.

[16]  J. Jeon,et al.  Ethyl pyruvate has an anti-inflammatory effect by inhibiting ROS-dependent STAT signaling in activated microglia. , 2008, Free radical biology & medicine.

[17]  P. Colditz,et al.  Post-insult minocycline treatment attenuates hypoxia-ischemia-induced neuroinflammation and white matter injury in the neonatal rat: a comparison of two different dose regimens , 2008, International Journal of Developmental Neuroscience.

[18]  E. Ling,et al.  Amoeboid Microglia in the Periventricular White Matter Induce Oligodendrocyte Damage through Expression of Proinflammatory Cytokines via MAP Kinase Signaling Pathway in Hypoxic Neonatal Rats , 2008, Brain pathology.

[19]  S. Back,et al.  Arrested oligodendrocyte lineage maturation in chronic perinatal white matter injury , 2008, Annals of neurology.

[20]  T. James,et al.  Exogenous Ethyl Pyruvate versus Pyruvate during Metabolic Recovery after Oxidative Stress in Neonatal Rat Cerebrocortical Slices , 2007, Anesthesiology.

[21]  N. Zhong,et al.  Ethyl Pyruvate Improves Survival and Ameliorates Distant Organ Injury in Rats With Severe Acute Pancreatitis , 2007, Pancreas.

[22]  S. Han,et al.  Ethyl pyruvate induces necrosis-to-apoptosis switch and inhibits high mobility group box protein 1 release in A549 lung adenocarcinoma cells. , 2007, International journal of molecular medicine.

[23]  S. Back,et al.  Maturation-Dependent Vulnerability of Perinatal White Matter in Premature Birth , 2007, Stroke.

[24]  L. Fan,et al.  Minocycline alleviates hypoxic–ischemic injury to developing oligodendrocytes in the neonatal rat brain , 2006, Neuroscience.

[25]  P. Han,et al.  Ethyl pyruvate attenuates kainic acid‐induced neuronal cell death in the mouse hippocampus , 2006, Journal of neuroscience research.

[26]  A. Leviton,et al.  Inflammation, brain damage and visual dysfunction in preterm infants. , 2006, Seminars in fetal & neonatal medicine.

[27]  Shuying Lin,et al.  Neuroprotection of α-phenyl-n-tert-butyl-nitrone on the neonatal white matter is associated with anti-inflammation , 2006, Neuroscience Letters.

[28]  L. Fan,et al.  IGF-1 protects oligodendrocyte progenitor cells and improves neurological functions following cerebral hypoxia–ischemia in the neonatal rat , 2005, Brain Research.

[29]  Jung‐Bin Kim,et al.  Anti-inflammatory mechanism is involved in ethyl pyruvate-mediated efficacious neuroprotection in the postischemic brain , 2005, Brain Research.

[30]  P. Han,et al.  Inhibition of the Cerebral Ischemic Injury by Ethyl Pyruvate With a Wide Therapeutic Window , 2005, Stroke.

[31]  J. Volpe Encephalopathy of Prematurity Includes Neuronal Abnormalities , 2005, Pediatrics.

[32]  M. Cheeran,et al.  Role of Microglia in Central Nervous System Infections , 2004, Clinical Microbiology Reviews.

[33]  H. Kinney,et al.  Developmental Lag in Superoxide Dismutases Relative to Other Antioxidant Enzymes in Premyelinated Human Telencephalic White Matter , 2004, Journal of neuropathology and experimental neurology.

[34]  D. Ferriero,et al.  Selective vulnerability in the developing central nervous system. , 2004, Pediatric neurology.

[35]  J. Volpe Cerebral white matter injury of the premature infant-more common than you think. , 2003, Pediatrics.

[36]  G. Levi,et al.  Differential Lipid Peroxidation, Mn Superoxide, and bcl‐2 Expression Contribute to the Maturation‐Dependent Vulnerability of Oligodendrocytes to Oxidative Stress , 2003, Journal of neuropathology and experimental neurology.

[37]  K. Tracey,et al.  Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[38]  P. Rezaie,et al.  Periventricular leukomalacia, inflammation and white matter lesions within the developing nervous system , 2002, Neuropathology : official journal of the Japanese Society of Neuropathology.

[39]  J. Perlman,et al.  Apoptosis and White Matter Injury in Preterm Infants , 2002, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

[40]  D. Holtzman,et al.  Selective Vulnerability of Late Oligodendrocyte Progenitors to Hypoxia–Ischemia , 2002, The Journal of Neuroscience.

[41]  H. Kinney,et al.  Late Oligodendrocyte Progenitors Coincide with the Developmental Window of Vulnerability for Human Perinatal White Matter Injury , 2001, The Journal of Neuroscience.

[42]  H. Okano,et al.  Caspases determine the vulnerability of oligodendrocytes in the ischemic brain. , 2000, The Journal of clinical investigation.

[43]  M. Fink Ethyl pyruvate: a novel treatment for sepsis. , 2007, Novartis Foundation symposium.

[44]  S. Korsmeyer,et al.  Bcl-2 gene family in the nervous system. , 1997, Annual review of neuroscience.