Mitochondrial DNA copy number is reduced in male combat veterans with PTSD

[1]  H. Kao,et al.  Alterations of Mitochondrial DNA Copy Number and Telomere Length With Early Adversity and Psychopathology , 2016, Biological Psychiatry.

[2]  L. Scorrano,et al.  Mitochondria: from cell death executioners to regulators of cell differentiation. , 2014, Trends in cell biology.

[3]  Nicole M. Taylor,et al.  Proinflammatory milieu in combat-related PTSD is independent of depression and early life stress , 2014, Brain, Behavior, and Immunity.

[4]  T. Jovanović,et al.  Telomere shortening and immune activity in war veterans with posttraumatic stress disorder , 2014, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[5]  Yan A. Su,et al.  Mitochondrial Gene Expression Profiles and Metabolic Pathways in the Amygdala Associated with Exaggerated Fear in an Animal Model of PTSD , 2014, Front. Neurol..

[6]  Vincent Procaccio,et al.  Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming , 2014, Proceedings of the National Academy of Sciences.

[7]  R. Schnellmann,et al.  Agonism of the 5-Hydroxytryptamine 1F Receptor Promotes Mitochondrial Biogenesis and Recovery from Acute Kidney Injury , 2014, The Journal of Pharmacology and Experimental Therapeutics.

[8]  M. Miller,et al.  Traumatic stress, oxidative stress and posttraumatic stress disorder: neurodegeneration and the accelerated-aging hypothesis , 2014, Molecular Psychiatry.

[9]  Cheng-Chen Chang,et al.  Mitochondrial DNA variation and increased oxidative damage in euthymic patients with bipolar disorder , 2014, Psychiatry and clinical neurosciences.

[10]  C. Dalgård,et al.  Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly , 2014, Human Genetics.

[11]  K. Xia,et al.  Leukocyte Mitochondrial DNA Copy Number in Blood Is Not Associated with Major Depressive Disorder in Young Adults , 2014, PloS one.

[12]  Bruce S. McEwen,et al.  Mitochondrial allostatic load puts the 'gluc' back in glucocorticoids , 2014, Nature Reviews Endocrinology.

[13]  Robert W. Taylor,et al.  Clinical and molecular characteristics of mitochondrial DNA depletion syndrome associated with neonatal cholestasis and liver failure. , 2014, The Journal of pediatrics.

[14]  Ji-Won Lee,et al.  Mitochondrial DNA Copy Number in Peripheral Blood Is Independently Associated with Visceral Fat Accumulation in Healthy Young Adults , 2014, International journal of endocrinology.

[15]  S. Shinjo,et al.  Leukocyte mitochondrial DNA copy number in bipolar disorder , 2014, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[16]  T. Levine,et al.  Posttraumatic Stress Disorder and Cardiometabolic Disease , 2013, Cardiology.

[17]  J. Francis,et al.  Inflammation and Oxidative Stress Are Elevated in the Brain, Blood, and Adrenal Glands during the Progression of Post-Traumatic Stress Disorder in a Predator Exposure Animal Model , 2013, PloS one.

[18]  T. Elbert,et al.  N-glycosylation profiling of plasma provides evidence for accelerated physiological aging in post-traumatic stress disorder , 2013, Translational Psychiatry.

[19]  P. Yadava,et al.  Telomerase and its extracurricular activities , 2013, Cellular & Molecular Biology Letters.

[20]  Janet B W Williams,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[21]  A. Young,et al.  Glucocorticoids Increase Protein Carbonylation and Mitochondrial Dysfunction , 2013, Hormone and Metabolic Research.

[22]  H. Torrell,et al.  Mitochondrial DNA (mtDNA) in brain samples from patients with major psychiatric disorders: Gene expression profiles, MtDNA content and presence of the MtDNA common deletion , 2013, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[23]  A. Bratić,et al.  The role of mitochondria in aging. , 2013, The Journal of clinical investigation.

[24]  Rick B. Vega,et al.  Transcriptional integration of mitochondrial biogenesis , 2012, Trends in Endocrinology & Metabolism.

[25]  J. Kolesar,et al.  Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number. , 2012, Biochimica et biophysica acta.

[26]  Jung-ha Kim,et al.  The relationship between leukocyte mitochondrial DNA contents and metabolic syndrome in postmenopausal women , 2012, Menopause.

[27]  P. Landi,et al.  Psychiatric disorders and mitochondrial dysfunctions. , 2012, European review for medical and pharmacological sciences.

[28]  D. Kozaric-Kovacic,et al.  Oxidative stress markers in patients with post-traumatic stress disorder. , 2011, Collegium antropologicum.

[29]  A. Psarra,et al.  Glucocorticoids induce mitochondrial gene transcription in HepG2 cells: role of the mitochondrial glucocorticoid receptor. , 2011, Biochimica et biophysica acta.

[30]  J. Davis,et al.  Exercise training increases mitochondrial biogenesis in the brain. , 2011, Journal of applied physiology.

[31]  Thomas Metzler,et al.  Childhood Trauma Associated with Short Leukocyte Telomere Length in Posttraumatic Stress Disorder , 2011, Biological Psychiatry.

[32]  Eosu Kim,et al.  Leukocyte mitochondrial DNA (mtDNA) content is associated with depression in old women. , 2011, Archives of gerontology and geriatrics.

[33]  E. Walker,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[34]  S. Fuke,et al.  Regional variation in mitochondrial DNA copy number in mouse brain. , 2011, Biochimica et biophysica acta.

[35]  I. Hertz-Picciotto,et al.  Mitochondrial dysfunction in autism. , 2010, JAMA.

[36]  P. Schnurr,et al.  Adaptation to extreme stress: post-traumatic stress disorder, neuropeptide Y and metabolic syndrome , 2010, Experimental biology and medicine.

[37]  P. Chinnery,et al.  OPA1 mutations cause cytochrome c oxidase deficiency due to loss of wild-type mtDNA molecules , 2010, Human molecular genetics.

[38]  R. Schnellmann,et al.  5-Hydroxytryptamine Receptor Stimulation of Mitochondrial Biogenesis , 2010, Journal of Pharmacology and Experimental Therapeutics.

[39]  E. Ravussin,et al.  The role of mitochondria in health and disease. , 2009, Current opinion in pharmacology.

[40]  G. Saretzki Telomerase, mitochondria and oxidative stress , 2009, Experimental Gerontology.

[41]  B. McEwen,et al.  Glucocorticoid receptors modulate mitochondrial function , 2009, Communicative & integrative biology.

[42]  A. Psarra,et al.  Glucocorticoid receptors and other nuclear transcription factors in mitochondria and possible functions. , 2009, Biochimica et biophysica acta.

[43]  Yidong Bai,et al.  Number matters: control of mammalian mitochondrial DNA copy number. , 2009, Journal of genetics and genomics = Yi chuan xue bao.

[44]  M. Spitz,et al.  Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma. , 2008, Journal of the National Cancer Institute.

[45]  Yan A. Su,et al.  Dysregulated Mitochondrial Genes and Networks with Drug Targets in Postmortem Brain of Patients with Posttraumatic Stress Disorder (PTSD) Revealed by Human Mitochondria-Focused cDNA Microarrays , 2008, International journal of biological sciences.

[46]  S. Komoly,et al.  Variations in Mitochondrial DNA Copy Numbers in MS Brains , 2008, Journal of Molecular Neuroscience.

[47]  G. Saretzki,et al.  Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress , 2008, Journal of Cell Science.

[48]  J. Parr,et al.  Liver mtDNA content increases during development: a comparison of methods and the importance of age- and tissue-specific controls for the diagnosis of mtDNA depletion. , 2007, Mitochondrion.

[49]  J. Reitsma,et al.  Cortisol and post-traumatic stress disorder in adults , 2007, British Journal of Psychiatry.

[50]  Tsu-Kung Lin,et al.  Early Stage of Biliary Atresia Is Associated With Significant Changes in 8-Hydroxydeoxyguanosine and Mitochondrial Copy Number , 2007, Journal of pediatric gastroenterology and nutrition.

[51]  Roger Bolus,et al.  Psychometric Properties of the Early Trauma Inventory–Self Report , 2007, The Journal of nervous and mental disease.

[52]  Takahiko Hara,et al.  The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells , 2007, Nature Genetics.

[53]  B. Bogerts,et al.  Quantification of total mitochondrial DNA and mitochondrial common deletion in the frontal cortex of patients with schizophrenia and bipolar disorder , 2007, Journal of Neural Transmission.

[54]  Patrick F. Chinnery,et al.  Mitochondrial DNA polymerase-γ and human disease , 2006 .

[55]  R. Myers,et al.  Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders , 2006, Molecular Psychiatry.

[56]  E. Nisoli,et al.  Nitric oxide and mitochondrial biogenesis , 2006, Journal of Cell Science.

[57]  B. Spiegelman,et al.  Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. , 2006, Endocrine reviews.

[58]  K. Iwamoto,et al.  Quantitative analysis of mitochondrial DNA deletions in the brains of patients with bipolar disorder and schizophrenia. , 2005, The international journal of neuropsychopharmacology.

[59]  L. Wong,et al.  Simultaneous detection and quantification of mitochondrial DNA deletion(s), depletion, and over-replication in patients with mitochondrial disease. , 2005, The Journal of molecular diagnostics : JMD.

[60]  Guido Davidzon,et al.  Mitochondrial DNA and disease , 2005, Annals of medicine.

[61]  K. Nair,et al.  Decline in skeletal muscle mitochondrial function with aging in humans. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[62]  Yau-Huei Wei,et al.  Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress. , 2005, The international journal of biochemistry & cell biology.

[63]  R. Scarpulla,et al.  Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. , 2004, Genes & development.

[64]  E. Clementi,et al.  Mitochondrial Biogenesis in Mammals: The Role of Endogenous Nitric Oxide , 2003, Science.

[65]  I. Liberzon,et al.  Psychopharmacological treatment in PTSD: a critical review. , 2002, Journal of psychiatric research.

[66]  J. Leckman,et al.  Characteristics of acute stress symptoms and nitric oxide concentration in young rescue workers in Taiwan , 2002, Psychiatry Research.

[67]  Robert W. Taylor,et al.  Detection and quantification of mitochondrial DNA deletions in individual cells by real-time PCR. , 2002, Nucleic acids research.

[68]  E. Blackburn,et al.  Telomeres and telomerase. , 2002, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[69]  Y. Pak,et al.  Mitochondrial transcription factor A (mtTFA) and diabetes. , 2001, Diabetes research and clinical practice.

[70]  I. Scheffler,et al.  Mitochondria make a come back. , 2001, Advanced drug delivery reviews.

[71]  C. W. Harris,et al.  Effects of mental stress on brachial artery flow-mediated vasodilation in healthy normal individuals. , 2000, American heart journal.

[72]  G. Attardi,et al.  Tight Control of Respiration by NADH Dehydrogenase ND5 Subunit Gene Expression in Mouse Mitochondria , 2000, Molecular and Cellular Biology.

[73]  C. A. Morgan,et al.  Neurotransmitter alterations in PTSD: catecholamines and serotonin. , 1999, Seminars in clinical neuropsychiatry.

[74]  J. Bugajski Social stress adapts signaling pathways involved in stimulation of the hypothalamic-pituitary-adrenal axis. , 1999, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

[75]  K. Park,et al.  Decreased mitochondrial DNA content in peripheral blood precedes the development of non-insulin-dependent diabetes mellitus. , 1998, Diabetes research and clinical practice.

[76]  J. Bremner,et al.  The effects of stress on memory and the hippocampus throughout the life cycle: Implications for childhood development and aging , 1998, Development and Psychopathology.

[77]  H. Akil,et al.  Nitric oxide in the stress axis. , 1998, Histology and histopathology.

[78]  E. Shoubridge,et al.  Mitochondrial DNA depletion: prevalence in a pediatric population referred for neurologic evaluation. , 1996, Pediatric neurology.

[79]  G. Kraal,et al.  Acute stress affects cytokines and nitric oxide production by alveolar macrophages differently. , 1995, American journal of respiratory and critical care medicine.

[80]  D. Watson,et al.  Development and validation of brief measures of positive and negative affect: the PANAS scales. , 1988, Journal of personality and social psychology.

[81]  F. David,et al.  Statistical Estimates and Transformed Beta-Variables. , 1960 .

[82]  V. S. Miakotnykh,et al.  [Age-related aspects of the extent of lipid metabolism and post-traumatic stress disorders among veterans of modern warfare]. , 2013, Advances in gerontology = Uspekhi gerontologii.

[83]  Torgashov Mn,et al.  [Age-related aspects of the extent of lipid metabolism and post-traumatic stress disorders among veterans of modern warfare]. , 2013 .

[84]  J. Auwerx,et al.  Regulation of PGC-1 a , a nodal regulator of mitochondrial biogenesis 1 – 4 , 2011 .

[85]  L. Chin,et al.  Telomere dysfunction induces metabolic and mitochondrial compromise , 2011, Nature.

[86]  Ruifang Niu,et al.  Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients , 2007, IUBMB life.

[87]  P. Chinnery,et al.  Mitochondrial DNA polymerase-gamma and human disease. , 2006, Human molecular genetics.

[88]  R. Yehuda,et al.  Neuroendocrine aspects of PTSD. , 2005, Handbook of experimental pharmacology.

[89]  R. Yehuda Biology of posttraumatic stress disorder. , 2000, The Journal of clinical psychiatry.

[90]  C. Moyes,et al.  Regulation of muscle mitochondrial design. , 1998, The Journal of experimental biology.

[91]  M. First,et al.  Structured clinical interview for DSM-IV axis I disorders : SCID-I : clinical version : scoresheet , 1997 .

[92]  M. First,et al.  Structured clinical interview for DSM-IV axis I disorders : SCID-I: clinical version : administration booklet , 1996 .

[93]  Dennis S. Charney,et al.  A CLINICIAN RATING SCALE FOR ASSESSING CURRENT AND LIFETIME PTSD: THE CAPS-1 , 1990 .

[94]  Cortisol and Posttraumatic Stress Disorder in Adults : a Systematic Review and Meta-Analysis , 2022 .