TRbeta is the critical thyroid hormone receptor isoform in T3-induced proliferation of hepatocytes and pancreatic acinar cells.

[1]  Thomas S. Scanlan,et al.  Sobetirome: a case history of bench-to-clinic drug discovery and development , 2010, Heart Failure Reviews.

[2]  A. Pingitore,et al.  The role of thyroid hormone in the pathophysiology of heart failure: clinical evidence , 2010, Heart Failure Reviews.

[3]  L. Boscá,et al.  Mice Lacking Thyroid Hormone Receptor β Show Enhanced Apoptosis and Delayed Liver Commitment for Proliferation after Partial Hepatectomy , 2010, PloS one.

[4]  E. Kress,et al.  Thyroid hormones and the control of cell proliferation or cell differentiation: Paradox or duality? , 2009, Molecular and Cellular Endocrinology.

[5]  P. Ladenson,et al.  Thyroid hormone antagonists: potential medical applications and structure activity relationships. , 2009, Current medicinal chemistry.

[6]  R. Schmid,et al.  The role of the Bcl-3 proto-oncogene in thyroid hormone-induced liver cell proliferation. , 2009, Artificial organs.

[7]  M. Pibiri,et al.  Thyroid hormone receptor ligands induce regression of rat preneoplastic liver lesions causing their reversion to a differentiated phenotype , 2009, Hepatology.

[8]  J. Baxter,et al.  Thyroid hormone mimetics: potential applications in atherosclerosis, obesity and type 2 diabetes , 2009, Nature Reviews Drug Discovery.

[9]  E. Kress,et al.  The Frizzled-related sFRP2 Gene Is a Target of Thyroid Hormone Receptor α1 and Activates β-Catenin Signaling in Mouse Intestine* , 2009, Journal of Biological Chemistry.

[10]  D. Bell,et al.  Species-specific kinetics and zonation of hepatic DNA synthesis induced by ligands of PPARalpha. , 2008, Toxicological sciences : an official journal of the Society of Toxicology.

[11]  A. Berkenstam,et al.  The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans , 2008, Proceedings of the National Academy of Sciences.

[12]  G. M. Ledda-Columbano,et al.  The Thyroid Hormone Receptor-β Agonist GC-1 Induces Cell Proliferation in Rat Liver and Pancreas , 2006 .

[13]  E. Kress,et al.  Thyroid Hormone Receptor α1 Directly Controls Transcription of the β-Catenin Gene in Intestinal Epithelial Cells , 2006, Molecular and Cellular Biology.

[14]  G. M. Ledda-Columbano,et al.  Thyroid hormone induces cyclin D1 nuclear translocation and DNA synthesis in adult rat cardiomyocytes , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[15]  R. Malik,et al.  Exogenous Thyroid Hormone Induces Liver Enlargement, Whilst Maintaining Regenerative Potential—A Study Relevant to Donor Preconditioning , 2005, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[16]  J. Baxter,et al.  Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[17]  G. M. Ledda-Columbano,et al.  Induction of pancreatic acinar cell proliferation by thyroid hormone. , 2005, The Journal of endocrinology.

[18]  Paul Webb,et al.  Selective activation of thyroid hormone signaling pathways by GC-1: a new approach to controlling cholesterol and body weight , 2004, Trends in Endocrinology & Metabolism.

[19]  F. Greenspan,et al.  Basic & Clinical Endocrinology , 2003 .

[20]  R. Walther,et al.  Expression of Thyroid Hormone Receptor Isoform α1 in Pancreatic Islets , 2003 .

[21]  J. Samarut,et al.  Thyroid hormone receptors: lessons from knockout and knock-in mutant mice , 2003, Trends in Endocrinology & Metabolism.

[22]  N. Lee,et al.  Patterns of liver gene expression governed by TRbeta. , 2002, Molecular endocrinology.

[23]  J. Samarut,et al.  Genetic Analysis Reveals Different Functions for the Products of the Thyroid Hormone Receptor α Locus , 2001, Molecular and Cellular Biology.

[24]  P. Yen,et al.  Physiological and molecular basis of thyroid hormone action. , 2001, Physiological reviews.

[25]  M. Pibiri,et al.  Cyclin D1 is an early target in hepatocyte proliferation induced by thyroid hormone (T3). , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[26]  B. Gloss,et al.  The Thyroid Hormone Receptor-β-Selective Agonist GC-1 Differentially Affects Plasma Lipids and Cardiac Activity. , 2000, Endocrinology.

[27]  P. Meltzer,et al.  Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray. , 2000, Molecular endocrinology.

[28]  M. Pibiri,et al.  Cell proliferation induced by 3,3',5-triiodo-L-thyronine is associated with a reduction in the number of preneoplastic hepatic lesions. , 1999, Carcinogenesis.

[29]  J. Samarut,et al.  Different functions for the thyroid hormone receptors TRα and TRβ in the control of thyroid hormone production and post‐natal development , 1999 .

[30]  C. Foster,et al.  Proliferation of parenchymal epithelial cells enhanced in chronic pancreatitis , 1998 .

[31]  J. Baxter,et al.  A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor. , 1998, Chemistry & biology.

[32]  T. Ohmura,et al.  Induction of cellular DNA synthesis in the pancreas and kidneys of rats by peroxisome proliferators, 9-cis retinoic acid, and 3,3',5-triiodo-L-thyronine. , 1997, Cancer research.

[33]  F. Epstein,et al.  The molecular basis of thyroid hormone action. , 1994, The New England journal of medicine.

[34]  L. Baxter,et al.  A Second Pathway for Regeneration of Adult Exocrine and Endocrine Pancreas: A Possible Recapitulation of Embryonic Development , 1993, Diabetes.

[35]  D. V. van Thiel,et al.  Hepatocyte proliferation and gene expression induced by triiodothyronine in vivo and in vitro , 1993, Hepatology.

[36]  M. Lazar Thyroid hormone receptors: multiple forms, multiple possibilities. , 1993, Endocrine reviews.

[37]  N. Ling,et al.  Quantitation of rat tissue thyroid hormone binding receptor isoforms by immunoprecipitation of nuclear triiodothyronine binding capacity. , 1992, The Journal of biological chemistry.

[38]  L. Boros,et al.  Essential Role of Cholecystokinin in Pancreatic Regeneration After 60% Distal Resection in Rats , 1991, Pancreas.

[39]  S. Bonner-Weir,et al.  Discordance of Exocrine and Endocrine Growth After 90% Pancreatectomy in Rats , 1988, Diabetes.

[40]  E. C. Jorgensen,et al.  Comparative effects of 3,5-dimethyl-3'-isopropyl-L-thyronine (DIMIT) and 3,5-diiodo-3'-isopropylthyroacetic acid (IpTA2) on body weight gain and lipid metabolism in genetically obese Zucker rats. , 1986, Biochemical pharmacology.

[41]  P. Nilsson-ehle,et al.  Experimental Hyperthyroidism in Man: Effects on Plasma Lipoproteins, Lipoprotein Lipase and Hepatic Lipase , 1983, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[42]  H. Samuels,et al.  Molecular Basis of Thyroid Hormone Action , 1983 .

[43]  Sidney H. Ingbar,et al.  The Thyroid Gland. , 1965 .

[44]  S. Werner The Thyroid A Fundamental and Clinical Text , 1957 .

[45]  Shih-Ming Huang,et al.  Human Spot 14 protein is a p53-dependent transcriptional coactivator via the recruitment of thyroid receptor and Zac1. , 2008, The international journal of biochemistry & cell biology.

[46]  E. Kress,et al.  Thyroid hormone receptor alpha1 directly controls transcription of the beta-catenin gene in intestinal epithelial cells. , 2006, Molecular and cellular biology.

[47]  M. Puzianowska-Kuźnicka,et al.  Thyroid hormones and their receptors in the regulation of cell proliferation. , 2006, Acta biochimica Polonica.

[48]  M. Pibiri,et al.  The thyroid hormone receptor-beta agonist GC-1 induces cell proliferation in rat liver and pancreas. , 2006, Endocrinology.

[49]  B Gerbert,et al.  [Thyroid hormone and the cardiovascular system]. , 2005, Deutsche medizinische Wochenschrift.

[50]  D. Forrest,et al.  Functions of thyroid hormone receptors in mice. , 2000, Thyroid : official journal of the American Thyroid Association.

[51]  J. Samarut,et al.  Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development. , 1999, The EMBO journal.

[52]  C. Foster,et al.  Proliferation of parenchymal epithelial cells enhanced in chronic pancreatitis , 1998, The Journal of pathology.

[53]  S. Pemrick,et al.  The retinoid receptors. , 1994, Leukemia.

[54]  M. Sporn,et al.  The Retinoids : biology, chemistry, and medicine , 1994 .

[55]  Pemrick Sm,et al.  The retinoid receptors. , 1994 .

[56]  R. Eaton,et al.  The effects of altered thyroid status on lipid metabolism in the genetic hyperlipemic Zucker rat. , 1981, Atherosclerosis.

[57]  Karl H. Pribram,et al.  Functions of the , 1954 .

[58]  R. M.,et al.  The Thyroid Gland , 1894, Nature.