Frequent phosphatidylinositol-3-kinase mutations in proliferative breast lesions
暂无分享,去创建一个
[1] Kenric Leung,et al. The Life History of 21 Breast Cancers , 2015, Cell.
[2] M. Troxell,et al. Frequent PIK3CA Mutations in Radial Scars , 2013, Diagnostic molecular pathology : the American journal of surgical pathology, part B.
[3] M. Troxell,et al. PIK3CA-AKT pathway mutations in micropapillary breast carcinoma. , 2013, Human pathology.
[4] A. González-Angulo,et al. Defining biomarkers to predict sensitivity to PI3K/Akt/mTOR pathway inhibitors in breast cancer. , 2013, Cancer treatment reviews.
[5] M. Troxell,et al. Novel method for PIK3CA mutation analysis: locked nucleic acid--PCR sequencing. , 2013, The Journal of molecular diagnostics : JMD.
[6] Serafim Batzoglou,et al. Genome evolution during progression to breast cancer , 2013, Genome research.
[7] M. Troxell,et al. Mucinous breast carcinomas lack PIK3CA and AKT1 mutations. , 2012, Human pathology.
[8] Steven J. M. Jones,et al. Comprehensive molecular portraits of human breast tumors , 2012, Nature.
[9] A. Sivachenko,et al. Sequence analysis of mutations and translocations across breast cancer subtypes , 2012, Nature.
[10] M. Shackleton,et al. Physiological Levels of Pik3ca H1047R Mutation in the Mouse Mammary Gland Results in Ductal Hyperplasia and Formation of ERα-Positive Tumors , 2012, PloS one.
[11] A. Børresen-Dale,et al. The landscape of cancer genes and mutational processes in breast cancer , 2012, Nature.
[12] Joshua F. McMichael,et al. Whole Genome Analysis Informs Breast Cancer Response to Aromatase Inhibition , 2012, Nature.
[13] R. West,et al. Phosphatidylinositol-3-kinase pathway mutations are common in breast columnar cell lesions , 2012, Modern Pathology.
[14] S. Durinck,et al. Conditional activation of Pik3caH1047R in a knock-in mouse model promotes mammary tumorigenesis and emergence of mutations , 2012, Oncogene.
[15] M. Troxell. PIK3CA/AKT1 Mutations in Breast Carcinoma: a Comprehensive Review of Experimental and Clinical Studies , 2012 .
[16] Laura J. Winter,et al. Multiplex mutation screening by mass spectrometry evaluation of 820 cases from a personalized cancer medicine registry. , 2011, The Journal of molecular diagnostics : JMD.
[17] G. Mills,et al. Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and -independent mechanisms , 2011, Nature Medicine.
[18] A. Heguy,et al. PIK3CA mutations rarely demonstrate genotypic intratumoral heterogeneity and are selected for in breast cancer progression , 2011, Breast Cancer Research and Treatment.
[19] Rosette Lidereau,et al. Gene Expression Profiling Reveals New Aspects of PIK3CA Mutation in ERalpha-Positive Breast Cancer: Major Implication of the Wnt Signaling Pathway , 2010, PloS one.
[20] Funda Meric-Bernstam,et al. Deciphering the role of PI3K/Akt/mTOR pathway in breast cancer biology and pathogenesis. , 2010, Clinical breast cancer.
[21] F. Jin,et al. Genetic mutations and expression of p53 in non-invasive breast lesions. , 2010, Molecular medicine reports.
[22] D. Carrasco,et al. PIK3CA mutations in in situ and invasive breast carcinomas. , 2010, Cancer research.
[23] T. Speed,et al. PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in breast cancer , 2010 .
[24] M. Troxell,et al. Phosphatidylinositol-3-kinase and AKT1 mutations occur early in breast carcinoma , 2010, Breast Cancer Research and Treatment.
[25] Yue Chen,et al. PTEN mutation spectrum in breast cancers and breast hyperplasia , 2010, Journal of Cancer Research and Clinical Oncology.
[26] Hong Wang,et al. PIK3CA mutations mostly begin to develop in ductal carcinoma of the breast. , 2010, Experimental and molecular pathology.
[27] W. Gerald,et al. PIK3CA Mutation Associates with Improved Outcome in Breast Cancer , 2009, Clinical Cancer Research.
[28] S. Fuqua,et al. Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway. , 2009, Cancer research.
[29] Zhi Hu,et al. An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer. , 2008, Cancer research.
[30] H. Bu,et al. Evidence of chromosomal alterations in pure usual ductal hyperplasia as a breast carcinoma precursor. , 2008, Oncology reports.
[31] A. Marchetti,et al. Different Prognostic Roles of Mutations in the Helical and Kinase Domains of the PIK3CA Gene in Breast Carcinomas , 2007, Clinical Cancer Research.
[32] M. Knowles. Role of FGFR3 in urothelial cell carcinoma: biomarker and potential therapeutic target , 2007, World Journal of Urology.
[33] M. Knowles,et al. FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer , 2007, The Journal of pathology.
[34] Spyro Mousses,et al. A transforming mutation in the pleckstrin homology domain of AKT1 in cancer , 2007, Nature.
[35] I. Ellis,et al. Columnar Cell Lesions of the Breast: The Missing Link in Breast Cancer Progression?: A Morphological and Molecular Analysis , 2005, The American journal of surgical pathology.
[36] J. Olson,et al. Estrogen receptor α (ESR1) mutant A908G is not a common feature in benign and malignant proliferations of the breast , 2004, Genes, chromosomes & cancer.
[37] S. Lakhani,et al. The diagnosis and management of pre-invasive breast disease: Genetic alterations in pre-invasive lesions , 2003, Breast Cancer Research.
[38] A. Vincent-Salomon,et al. Columnar Cell Lesions of the Breast , 2003, Advances in anatomic pathology.
[39] S. Lakhani,et al. Comparative genomic hybridization analysis of bilateral hyperplasia of usual type of the breast , 2003, The Journal of pathology.
[40] S. Devries,et al. Genetic changes in paired atypical and usual ductal hyperplasia of the breast by comparative genomic hybridization. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.
[41] S. Hilsenbeck,et al. A hypersensitive estrogen receptor-alpha mutation in premalignant breast lesions. , 2000, Cancer research.
[42] H. Ozçelik,et al. p53 protein accumulation and mutations in normal and benign breast tissue , 2000, International journal of cancer.
[43] S. Lakhani. The transition from hyperplasia to invasive carcinoma of the breast , 1999, The Journal of pathology.
[44] P. O’Connell,et al. Analysis of loss of heterozygosity in 399 premalignant breast lesions at 15 genetic loci. , 1998, Journal of the National Cancer Institute.
[45] I. Andrulis,et al. p53 mutations in mammary ductal carcinoma in situ but not in epithelial hyperplasias. , 1998, Cancer research.
[46] R. Millikan,et al. p53 mutations in benign breast tissue. , 1995, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[47] S J Schnitt,et al. Interobserver Reproducibility in the Diagnosis of Ductal Proliferative Breast Lesions Using Standardized Criteria , 1992, The American journal of surgical pathology.
[48] Steven J. M. Jones,et al. Comprehensive molecular portraits of human breast tumours , 2013 .
[49] Sunil R. Lakhani,et al. WHO classification of tumours of the breast , 2012 .
[50] Janice Patterson,et al. High prevalence of PIK3CA/AKT pathway mutations in papillary neoplasms of the breast , 2010, Modern Pathology.
[51] Ruan Qiu-ron. Intraductal proliferative lesions of the breast: a clinicopathologic analysis , 2006 .
[52] T. Toyama,et al. Estrogen receptor α mutation (A-to-G transition at nucleotide 908) is not found in different types of breast lesions from japanese women , 2003, Breast cancer.
[53] M. Stratton,et al. Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations. , 1996, Laboratory investigation; a journal of technical methods and pathology.