The shape of the distal femur: a palaeopathological comparison of eburnated and non-eburnated femora

OBJECTIVES To determine the difference in shape of the distal femur, viewed axially in two dimensions, between eburnated and non-eburnated femora. METHODS A comparison of 52 non-eburnated and 16 eburnated femora drawn from a large archeological skeletal population. Eburnation was taken to indicate late stage osteoarthritis. Shape variability, based on landmarks, was quantified using a principal components analysis after a Procrustes alignment. RESULTS A statistically significant difference was found between the two groups. This was with respect to the patellar groove and the shape of the medial condyle. The latter difference is consistent with bone remodelling as a knee stabilising mechanism. CONCLUSIONS Anatomical shape can be quantified using an uncomplicated statistical technique. It was used to quantify the shape of the distal femur and demonstrate shape differences associated with osteoarthritis of the knee.

[1]  S. Casscells Gross pathological changes in the knee joint of the aged individual: a study of 300 cases. , 1978, Clinical orthopaedics and related research.

[2]  P. Revell A field guide to joint disease in archaeology , 1996 .

[3]  A. Cats,et al.  Epidemiology of osteoarthritis: Zoetermeer survey. Comparison of radiological osteoarthritis in a Dutch population with that in 10 other populations. , 1989, Annals of the rheumatic diseases.

[4]  E. Higgs Digging up Bones , 1969, Nature.

[5]  Jh. Kellgren Radiological assessment of osteoarthrosis , 1957 .

[6]  J. Gower Generalized procrustes analysis , 1975 .

[7]  P. Benya,et al.  Effects of valgus tibial angulation on cartilage degeneration in the rabbit knee , 1995, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[8]  K. Jacobsen,et al.  Osteoarthrosis following insufficiency of the cruciate ligaments in man. A clinical study. , 1977, Acta orthopaedica Scandinavica.

[9]  T. Spector,et al.  The relationship of obesity, fat distribution and osteoarthritis in women in the general population: the Chingford Study. , 1993, The Journal of rheumatology.

[10]  P. Bullough,et al.  The geometry of diarthrodial joints, its physiologic maintenance, and the possible significance of age-related changes in geometry-to-load distribution and the development of osteoarthritis. , 1981, Clinical orthopaedics and related research.

[11]  I. W. Wright Splines in Statistics , 1983 .

[12]  N. Lane Physical activity at leisure and risk of osteoarthritis. , 1996, Annals of the rheumatic diseases.

[13]  J. L. Marshall,et al.  Instability of the knee. A long-term experimental study in dogs. , 1971, The Journal of bone and joint surgery. American volume.

[14]  M. Moussa Rotational malalignment and femoral torsion in osteoarthritic knees with patellofemoral joint involvement. A CT scan study. , 1994, Clinical orthopaedics and related research.

[15]  R. Jurmain,et al.  Skeletal evidence of osteoarthritis: a palaeopathological perspective. , 1995, Annals of the rheumatic diseases.

[16]  P. Dieppe,et al.  Bone formers: osteophyte and enthesophyte formation are positively associated , 1997, Annals of the rheumatic diseases.

[17]  L. Draganich,et al.  The effect of marginal osteophytes on reduction of varus-valgus instability in osteoarthritic knees. , 1990, Arthritis and rheumatism.

[18]  P. Dieppe,et al.  The localization of osteoarthritis. , 1994, British journal of rheumatology.

[19]  D. Felson,et al.  Obesity and knee osteoarthritis. The Framingham Study. , 1988, Annals of internal medicine.

[20]  Casscells Sw Gross pathological changes in the knee joint of the aged individual: a study of 300 cases. , 1978 .

[21]  U. Wyss,et al.  Axial lower-limb alignment: comparison of knee geometry in normal volunteers and osteoarthritis patients. , 1997, Osteoarthritis and cartilage.

[22]  E. Radin,et al.  Bone and cartilage changes following experimental varus or valgus tibial angulation , 1990, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[23]  Y. Yoshioka,et al.  The anatomy and functional axes of the femur. , 1987, The Journal of bone and joint surgery. American volume.

[24]  H. Kaiser The varimax criterion for analytic rotation in factor analysis , 1958 .

[25]  J. Gillquist,et al.  Intercondylar notch measurements with special reference to anterior cruciate ligament surgery. , 1991, Clinical orthopaedics and related research.

[26]  M. Griffin,et al.  Patterns of knee arthrosis and patellar subluxation. , 1994, Clinical orthopaedics and related research.

[27]  C. Cooper,et al.  Mechanical and constitutional risk factors for symptomatic knee osteoarthritis: differences between medial tibiofemoral and patellofemoral disease. , 1994, The Journal of rheumatology.

[28]  E. Radin,et al.  What causes knee osteoarthrosis: are different compartments susceptible to different risk factors? , 1994, Journal of Rheumatology.

[29]  Timothy F. Cootes,et al.  Training Models of Shape from Sets of Examples , 1992, BMVC.

[30]  P. Bullough,et al.  INTERNATIONAL SYMPOSIUM ON ‘JOINT FAILURE’: RECENT ADVANCES IN STEOARTHRITIS AND RELATED DISORDERS: OSTEOARTHRITIS: PATHOGENESIS AND AETIOLOGY , 1984 .

[31]  L. Kazis,et al.  The prevalence of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study. , 1987, Arthritis and rheumatism.