The morbidity and the spectrum of applied drugs in shelter cats in the Czech Republic

Maintaining appropriate living conditions and good health of the animals should be one of the main priorities of cat shelters. The aim of this study was to assess the morbidity of shelter cats on the basis of analysis of the shelter health records in terms of the nature and quantity of medicaments and other supportive products administered in two no-kill shelters in the Czech Republic. The subject of the study were the health records of 1,884 cats, which were admitted to the selected shelters from 1.1.2013 to 31.12.2021 and their stay in the shelter was terminated in the monitored period. More than half of all cats whose records were analyzed had at least one health record made during their stay in the shelter. The overall length of stay of cats in the shelter (regardless of the outcome) in which one or more health records were found was significantly longer compared to the length of stay of cats without any health records. The highest number of health records was found in kittens <6 months old. Antibiotics, antiparasitics, and complementary/protective substances were the most used among all administered drugs. Broad-spectrum antibiotics have been administered to cats most often. In terms of classification of antibiotics according to the active substance, the most used antibiotics were penicillins, tetracyclines, and fluoroquinolones. Antibiotics were mostly used to treat diseases related to the upper and lower respiratory tract and their symptoms and gastrointestinal problems. The findings of the study contribute to understanding health problems and approaches to treating the shelter cats.

[1]  Kevin Horecka,et al.  Critical Problems for Research in Animal Sheltering, a Conceptual Analysis , 2022, Frontiers in Veterinary Science.

[2]  H. Mohammed,et al.  A Prospective Study of Growth Rate, Disease Incidence, and Mortality in Kittens Less than 9 Weeks of Age in Shelter and Foster Care , 2022, Journal of Applied Animal Welfare Science.

[3]  E. Voslářová,et al.  Changes in Health Indicators of Welfare in Group-Housed Shelter Cats , 2021, Frontiers in Veterinary Science.

[4]  M. Drigo,et al.  Prevalence and risk factors associated with cat parasites in Italy: a multicenter study , 2021, Parasites & vectors.

[5]  G. Fosgate,et al.  Short- and long-term effects of amoxicillin/clavulanic acid or doxycycline on the gastrointestinal microbiome of growing cats , 2021, bioRxiv.

[6]  U. Saarma,et al.  Endoparasite prevalence and infection risk factors among cats in an animal shelter in Estonia. , 2021, Folia parasitologica.

[7]  J. Lidbury,et al.  Effect of amoxicillin‐clavulanic acid on clinical scores, intestinal microbiome, and amoxicillin‐resistant Escherichia coli in dogs with uncomplicated acute diarrhea , 2020, Journal of veterinary internal medicine.

[8]  P. Tizzani,et al.  Otodectes cynotis in urban and peri-urban semi-arid areas: a widespread parasite in the cat population , 2020, Journal of Parasitic Diseases.

[9]  S. Perrucci,et al.  Gastrointestinal parasites in shelter cats of central Italy. , 2019, Veterinary parasitology, regional studies and reports.

[10]  Stephen Adeniyi Adefegha Antibiotics and Drug Pharmacology , 2019, Acta Scientific Pharmaceutical Sciences.

[11]  E. Voslářová,et al.  Comparison of Outcome Data for Shelter Dogs and Cats in the Czech Republic , 2019, Animals : an open access journal from MDPI.

[12]  J. Stavisky,et al.  Health and welfare in a multi-animal environment , 2019, Veterinary Record.

[13]  V. Barrs Feline Panleukopenia: A Re-emergent Disease. , 2019, The Veterinary clinics of North America. Small animal practice.

[14]  C. Lehner,et al.  Antimicrobial use for selected diseases in cats in Switzerland , 2019, BMC Veterinary Research.

[15]  J. Suchodolski,et al.  Effects of a synbiotic on the fecal microbiome and metabolomic profiles of healthy research cats administered clindamycin: a randomized, controlled trial , 2019, Gut microbes.

[16]  R. Grant,et al.  Clicker training increases exploratory behaviour and time spent at the front of the enclosure in shelter cats; Implications for welfare and adoption rates , 2019, Applied Animal Behaviour Science.

[17]  H. Billman-Jacobe,et al.  Population wide assessment of antimicrobial use in dogs and cats using a novel data source - A cohort study using pet insurance data. , 2018, Veterinary microbiology.

[18]  C. Mcmanus,et al.  Prevalence of enteropathogens in cats with and without diarrhea in four different management models for unowned cats in the southeast United States , 2018, The Veterinary Journal.

[19]  M. Rust The Biology and Ecology of Cat Fleas and Advancements in Their Pest Management: A Review , 2017, Insects.

[20]  E. Voslářová,et al.  Investigating Some of the Factors that Affect the Selection of Shelter Cats by Adopters in the Czech Republic , 2017 .

[21]  J. Dewulf,et al.  The impact of antimicrobial use guidelines on prescription habits in fourteen Flemish small animal practices , 2017 .

[22]  F. Sánchez-Vizcaíno,et al.  Use of cefovecin in a UK population of cats attending first-opinion practices as recorded in electronic health records , 2017, Journal of feline medicine and surgery.

[23]  G. Pinchbeck,et al.  Patterns of antimicrobial agent prescription in a sentinel population of canine and feline veterinary practices in the United Kingdom , 2017, Veterinary journal.

[24]  E. Voslářová,et al.  Rates of death and euthanasia for cats in no-kill shelters in the Czech Republic , 2017 .

[25]  J. Weese,et al.  Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases , 2017, Journal of veterinary internal medicine.

[26]  A. A. Pérez de León,et al.  First documentation of ivermectin resistance in Rhipicephalus sanguineus sensu lato (Acari: Ixodidae). , 2017, Veterinary parasitology.

[27]  K. Morgan,et al.  Faecal consistency and risk factors for diarrhoea and constipation in cats in UK rehoming shelters , 2017, Journal of feline medicine and surgery.

[28]  Jennifer E. Thomas,et al.  Ectoparasites of free-roaming domestic cats in the central United States. , 2016, Veterinary parasitology.

[29]  Y. Doi,et al.  Possible Transmission of mcr-1–Harboring Escherichia coli between Companion Animals and Human , 2016, Emerging infectious diseases.

[30]  A. Mateus,et al.  Characterisation of antimicrobial usage in cats and dogs attending UK primary care companion animal veterinary practices , 2016, Veterinary Record.

[31]  X. Manteca,et al.  Stress in owned cats: behavioural changes and welfare implications , 2016, Journal of feline medicine and surgery.

[32]  L. Sinn Factors affecting the selection of cats by adopters , 2016 .

[33]  P. Bennett,et al.  The Italian perception of the ideal companion dog , 2016 .

[34]  Marian C. Horzinek,et al.  WSAVA Guidelines for the vaccination of dogs and cats , 2016, The Journal of small animal practice.

[35]  S. Nykäsenoja,et al.  Large Outbreak Caused by Methicillin Resistant Staphylococcus pseudintermedius ST71 in a Finnish Veterinary Teaching Hospital – From Outbreak Control to Outbreak Prevention , 2014, PloS one.

[36]  S. Dawson,et al.  Surveillance of diarrhoea in small animal practice through the Small Animal Veterinary Surveillance Network (SAVSNET). , 2014, Veterinary journal.

[37]  S. Borriello,et al.  Antibiotics used most commonly to treat animals in Europe , 2014, Veterinary Record.

[38]  Savsnet SAVSNET the next stage: A report on the Small Animal Veterinary Surveillance Network , 2013 .

[39]  C. Phillips,et al.  Descriptive epidemiology of upper respiratory disease and associated risk factors in cats in an animal shelter in coastal western Canada. , 2013, The Canadian veterinary journal = La revue veterinaire canadienne.

[40]  L. Miller,et al.  Shelter medicine for veterinarians and staff. , 2012 .

[41]  L. Lee,et al.  Shelter Animal Management and Trends in Taiwan , 2012, Journal of applied animal welfare science : JAAWS.

[42]  J. Weese,et al.  Out-patient antimicrobial drug use in dogs and cats for new disease events from community companion animal practices in Ontario. , 2012, The Canadian veterinary journal = La revue veterinaire canadienne.

[43]  P. Kass,et al.  Associations among weight loss, stress, and upper respiratory tract infection in shelter cats. , 2012, Journal of the American Veterinary Medical Association.

[44]  H. Weng,et al.  Impact of the Economic Recession on Companion Animal Relinquishment, Adoption, and Euthanasia: A Chicago Animal Shelter's Experience , 2012, Journal of applied animal welfare science : JAAWS.

[45]  J. Weese,et al.  American College of Veterinary Internal Medicine Consensus Statements Enteropathogenic Bacteria in Dogs and Cats : Diagnosis , Epidemiology , Treatment and Control , 2011 .

[46]  L. Cohn Feline respiratory disease complex. , 2011, The Veterinary clinics of North America. Small animal practice.

[47]  A. Mateus,et al.  Antimicrobial usage in dogs and cats in first opinion veterinary practices in the UK. , 2011, The Journal of small animal practice.

[48]  S. Dawson,et al.  Antibacterial prescribing patterns in small animal veterinary practice identified via SAVSNET: the small animal veterinary surveillance network , 2011, Veterinary Record.

[49]  K. Hartmann,et al.  Suspected side effects of doxycycline use in dogs – a retrospective study of 386 cases , 2011, Veterinary Record.

[50]  C. Buffington,et al.  Idiopathic cystitis in domestic cats--beyond the lower urinary tract. , 2011, Journal of veterinary internal medicine.

[51]  J. Weese,et al.  Antimicrobial Use Guidelines for Treatment of Urinary Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases , 2011, Veterinary medicine international.

[52]  M. Lappin,et al.  Effect of the Probiotic Enterococcus faecium SF68 on Presence of Diarrhea in Cats and Dogs Housed in an Animal Shelter , 2011, Journal of veterinary internal medicine.

[53]  A. Iwasaki,et al.  Microbiota regulates immune defense against respiratory tract influenza A virus infection , 2011, Proceedings of the National Academy of Sciences.

[54]  M. Lappin,et al.  Detection of bacterial and viral organisms from the conjunctiva of cats with conjunctivitis and upper respiratory tract disease , 2010, Journal of feline medicine and surgery.

[55]  D. Jas,et al.  Onset of immunity in kittens after vaccination with a non-adjuvanted vaccine against feline panleucopenia, feline calicivirus and feline herpesvirus. , 2009, Veterinary journal.

[56]  P. Bennett,et al.  Admissions of Cats to Animal Welfare Shelters in Melbourne, Australia , 2009, Journal of applied animal welfare science : JAAWS.

[57]  G. Regula,et al.  Prescription patterns of antimicrobials in veterinary practices in Switzerland. , 2009, The Journal of antimicrobial chemotherapy.

[58]  G. P. Lambert,et al.  Stress-induced gastrointestinal barrier dysfunction and its inflammatory effects. , 2009, Journal of animal science.

[59]  A. Beynen,et al.  Indoor confinement and physical inactivity rather than the proportion of dry food are risk factors in the development of feline type 2 diabetes mellitus. , 2009, Veterinary journal.

[60]  N. Pedersen,et al.  Pathogenesis of feline enteric coronavirus infection , 2008, Journal of Feline Medicine & Surgery.

[61]  J. Murray,et al.  A study of risk factors for cat mortality in adoption centres of a UK cat charity , 2008, Journal of Feline Medicine & Surgery.

[62]  James R. Johnson,et al.  Escherichia coli colonization patterns among human household members and pets, with attention to acute urinary tract infection. , 2008, The Journal of infectious diseases.

[63]  A. Passantino Ethical aspects for veterinarians regarding antimicrobial drug use in Italy. , 2007, International journal of antimicrobial agents.

[64]  C. Gorrel,et al.  Treatment of a case of refractory feline chronic gingivostomatitis with feline recombinant interferon omega. , 2007, The Journal of small animal practice.

[65]  J. Foley,et al.  Epidemiologic evaluation of multiple respiratory pathogens in cats in animal shelters , 2005, Journal of feline medicine and surgery.

[66]  N. Pedersen,et al.  Common virus infections in cats, before and after being placed in shelters, with emphasis on feline enteric coronavirus , 2004, Journal of Feline Medicine & Surgery.

[67]  V. Wiebe,et al.  Fluoroquinolone-induced retinal degeneration in cats. , 2002, Journal of the American Veterinary Medical Association.

[68]  E. Greiner,et al.  Prevalence of ectoparasites in a population of feral cats from north central Florida during the summer. , 2002, Veterinary parasitology.

[69]  T. Walsh,et al.  Use of antimicrobial agents in veterinary medicine and food animal production. , 2001, International journal of antimicrobial agents.

[70]  C. Koblenzer Itching and the atopic skin. , 1999, The Journal of allergy and clinical immunology.

[71]  Harry Vennema,et al.  Feline Infectious Peritonitis Viruses Arise by Mutation from Endemic Feline Enteric Coronaviruses , 1998, Virology.

[72]  J. Scarlett,et al.  Overweight cats: prevalence and risk factors. , 1994, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

[73]  J. Griffin,et al.  Stress and immunity: a unifying concept. , 1989, Veterinary immunology and immunopathology.

[74]  S. Maxwell Rational prescribing: the principles of drug selection. , 2016, Clinical medicine.

[75]  Mandy B. A. Paterson,et al.  Cat admissions to RSPCA shelters in Queensland, Australia: description of cats and risk factors for euthanasia after entry. , 2013, Australian veterinary journal.

[76]  L. Lord,et al.  Sickness behaviors in response to unusual external events in healthy cats and cats with feline interstitial cystitis. , 2011, Journal of the American Veterinary Medical Association.

[77]  L. Larson,et al.  Age and long-term protective immunity in dogs and cats. , 2010, Journal of comparative pathology.

[78]  E. Thiry,et al.  Feline herpesvirus. , 2007, Veterinary research.

[79]  M. Niederman Principles of appropriate antibiotic use. , 2005, International journal of antimicrobial agents.

[80]  L. A. Gale,et al.  Evaluation of the effect of a long-term trap-neuter-return and adoption program on a free-roaming cat population. , 2003, Journal of the American Veterinary Medical Association.