Intramyocardial blood volume — implications for analysis of myocardial mechanical characteristics via in vivo imaging of the heart

Volume of intravascular blood within the myocardium can be estimated in the intact, in situ heart using fast CT. The ratio of increased roentgen opacity in the myocardium and in the aortic root was used to estimate the blood volume. In five dogs an average value of 13.4% of myocardium was estimated to be blood and in another nine dogs adenosine infusion into the pulmonary artery increased this value to 22%. A more direct estimate of this value in isolated hearts was obtained by perfusing the coronary circulation with dilute contrast agent. Values obtained ranged from 8% to 14% over a 75 mmHg to 110 mmHg perfusion pressure.

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