Targeting Notch signaling by γ-secretase inhibitor I enhances the cytotoxic effect of 5-FU in gastric cancer
暂无分享,去创建一个
[1] H-W Lee,et al. Activation of nuclear PTEN by inhibition of Notch signaling induces G2/M cell cycle arrest in gastric cancer , 2016, Oncogene.
[2] Seok-Jun Kim,et al. Cleaved CD44 intracellular domain supports activation of stemness factors and promotes tumorigenesis of breast cancer , 2015, Oncotarget.
[3] Kyung-Hee Chun,et al. Glucose Deprivation Triggers Protein Kinase C-dependent β-Catenin Proteasomal Degradation , 2015, The Journal of Biological Chemistry.
[4] Seok-Jun Kim,et al. Galectin-3 activates PPARγ and supports white adipose tissue formation and high-fat diet-induced obesity. , 2015, Endocrinology.
[5] J. Cheong,et al. Celastrol inhibits gastric cancer growth by induction of apoptosis and autophagy , 2014, BMB reports.
[6] I. Choi,et al. Ablation of galectin-3 induces p27KIP1-dependent premature senescence without oncogenic stress , 2014, Cell Death and Differentiation.
[7] T. Irimura,et al. Up-regulation of neogenin-1 increases cell proliferation and motility in gastric cancer , 2014, Oncotarget.
[8] Hugo J. Bellen,et al. Notch Signaling , 2014, Methods in Molecular Biology.
[9] J. Ro,et al. Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer , 2013, Oncotarget.
[10] I. Choi,et al. Acceleration of Gastric Tumorigenesis Through MKRN1-Mediated Posttranslational Regulation of p14ARF , 2012, Journal of the National Cancer Institute.
[11] T. Satoh,et al. S-1 for the treatment of gastrointestinal cancer , 2012, Expert opinion on pharmacotherapy.
[12] F. Ciardiello,et al. Current status of targeted therapies in advanced gastric cancer , 2012, Expert opinion on therapeutic targets.
[13] Seok-Jun Kim,et al. Galectin-3 increases the motility of mouse melanoma cells by regulating matrix metalloproteinase-1 expression , 2012, Experimental & Molecular Medicine.
[14] Ji‐Young Shin,et al. STAT3 silencing enhances the efficacy of the HSV.tk suicide gene in gastrointestinal cancer therapy , 2012, Clinical & Experimental Metastasis.
[15] M. Evgen’ev,et al. Parallelism and paradoxes on viability and the life span of two loss-of-function mutations: Heat shock protein transcriptional regulator hsf1 and l(2)gl tumor suppressor in Drosophila melanogaster , 2012, Biology Bulletin.
[16] Y. Bae,et al. MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7 , 2012, Breast Cancer Research.
[17] Seok-Jun Kim,et al. Development of microRNA-145 for therapeutic application in breast cancer. , 2011, Journal of controlled release : official journal of the Controlled Release Society.
[18] S. Gygi,et al. A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development. , 2011, Molecular cell.
[19] B. Langlois,et al. LRP-1 Promotes Cancer Cell Invasion by Supporting ERK and Inhibiting JNK Signaling Pathways , 2010, PloS one.
[20] V. Orian-Rousseau. CD44, a therapeutic target for metastasising tumours. , 2010, European journal of cancer.
[21] Ji‐Young Shin,et al. Silencing of galectin‐3 changes the gene expression and augments the sensitivity of gastric cancer cells to chemotherapeutic agents , 2010, Cancer science.
[22] M. Kuo,et al. The activated Notch1 signal pathway is associated with gastric cancer progression through cyclooxygenase-2. , 2009, Cancer research.
[23] A. Ferrando,et al. Oncogenic NOTCH1 Control of MYC and PI3K: Challenges and Opportunities for Anti-NOTCH1 Therapy in T-Cell Acute Lymphoblastic Leukemias and Lymphomas , 2008, Clinical Cancer Research.
[24] U. Lendahl,et al. Notch signaling mediates hypoxia-induced tumor cell migration and invasion , 2008, Proceedings of the National Academy of Sciences.
[25] A. Ferrando,et al. The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia , 2008, Cell cycle.
[26] Jian Zhang,et al. Notch signaling regulates the FOXP3 promoter through RBP-J- and Hes1-dependent mechanisms , 2008, Molecular and Cellular Biochemistry.
[27] J. Ajani,et al. Clinical benefit with docetaxel plus fluorouracil and cisplatin compared with cisplatin and fluorouracil in a phase III trial of advanced gastric or gastroesophageal cancer adenocarcinoma: the V-325 Study Group. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[28] G. Lockwood,et al. High-level JAG1 mRNA and protein predict poor outcome in breast cancer , 2007, Modern Pathology.
[29] Ali H. Brivanlou,et al. Signaling Pathways in Cancer and Embryonic Stem Cells , 2007, Stem Cell Reviews.
[30] I. Shih,et al. Notch Signaling, γ-Secretase Inhibitors, and Cancer Therapy: Figure 1. , 2007 .
[31] D. Srivastava,et al. Hrt and Hes negatively regulate Notch signaling through interactions with RBP-Jkappa. , 2006, Biochemical and biophysical research communications.
[32] Tian-Li Wang,et al. Notch3 gene amplification in ovarian cancer. , 2006, Cancer research.
[33] F. Alt,et al. Activating Notch1 mutations in mouse models of T-ALL. , 2005, Blood.
[34] A. Knowlton,et al. NFκB, heat shock proteins, HSF-1, and inflammation , 2006 .
[35] A. Knowlton,et al. NFkappaB, heat shock proteins, HSF-1, and inflammation. , 2006, Cardiovascular research.
[36] L. L. Reed,et al. Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells , 2005, Oncogene.
[37] G. Lockwood,et al. High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival. , 2005, Cancer research.
[38] S. Varambally,et al. JAGGED1 Expression Is Associated with Prostate Cancer Metastasis and Recurrence , 2004, Cancer Research.
[39] Jay S. Fine,et al. Chronic Treatment with the γ-Secretase Inhibitor LY-411,575 Inhibits β-Amyloid Peptide Production and Alters Lymphopoiesis and Intestinal Cell Differentiation* , 2004, Journal of Biological Chemistry.
[40] G. Higgins,et al. Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation. , 2004, The Journal of biological chemistry.
[41] M. Fortini,et al. Signalling: γ-Secretase-mediated proteolysis in cell-surface-receptor signalling , 2002, Nature Reviews Molecular Cell Biology.
[42] R. Dai,et al. Heat shock factor‐4 (HSF‐4a) is a repressor of HSF‐1 mediated transcription * , 2001, Journal of cellular biochemistry.
[43] G. Hahn,et al. Analysis of HSF-1 phosphorylation in A549 cells treated with a variety of stresses. , 1994, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.