Highly efficient and precise base editing by engineered dCas9-guide tRNA adenosine deaminase in rats

[1]  Nicole M. Gaudelli,et al.  Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage , 2017, Nature.

[2]  Eric Smalley CRISPR mouse model boom, rat model renaissance , 2016, Nature Biotechnology.

[3]  David R. Liu,et al.  Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage , 2016, Nature.

[4]  J. Joung,et al.  High-fidelity CRISPR-Cas9 variants with undetectable genome-wide off-targets , 2015, Nature.

[5]  J. Joung,et al.  Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition , 2015, Nature Biotechnology.

[6]  Martin J. Aryee,et al.  Engineered CRISPR-Cas9 nucleases with altered PAM specificities , 2015, Nature.

[7]  Lianfeng Zhang,et al.  Generation of eGFP and Cre knockin rats by CRISPR/Cas9 , 2014, The FEBS journal.

[8]  T. Mashimo,et al.  Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR–Cas platform , 2014, Nature Communications.

[9]  J. Keith Joung,et al.  Improving CRISPR-Cas nuclease specificity using truncated guide RNAs , 2014, Nature Biotechnology.

[10]  Jin-Soo Kim,et al.  Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases , 2014, Bioinform..

[11]  Lianfeng Zhang,et al.  Generating Rats with Conditional Alleles Using Crispr/cas9 Dear Editor, Generating Conditional Knockout Rats Using Crispr/cas9 2 Generating Conditional Knockout Rats Using Crispr/cas9 4 , 2022 .

[12]  Yongxiang Zhao,et al.  Heritable gene targeting in the mouse and rat using a CRISPR-Cas system , 2013, Nature Biotechnology.

[13]  H. Jacob,et al.  Rats! , 2009, Disease Models & Mechanisms.