Design and development of a novel genetic probe for the analysis of repressor-operator interactions.

[1]  J. Sambrook,et al.  Molecular Cloning: A Laboratory Manual , 2001 .

[2]  N. Jakubovics,et al.  Expression of the virulence‐related Sca (Mn2+) permease in Streptococcus gordonii is regulated by a diphtheria toxin metallorepressor‐like protein ScaR , 2000, Molecular microbiology.

[3]  J. Helmann,et al.  Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins , 2000, Molecular microbiology.

[4]  W. Hol,et al.  Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain. , 1999, Journal of molecular biology.

[5]  D. Ringe,et al.  Structure of the metal-ion-activated diphtheria toxin repressor/ tox operator complex , 1998, Nature.

[6]  M. Schmitt.  Transcription of the Corynebacterium diphtheriae hmuO gene is regulated by iron and heme , 1997, Infection and immunity.

[7]  D. Ringe,et al.  Identification of the primary metal ion-activation sites of the diphtheria tox represser by X-ray crystallography and site-directed mutational analysis , 1996, Nature Structural Biology.

[8]  I. Smith,et al.  Characterization of an iron-dependent regulatory protein (IdeR) of Mycobacterium tuberculosis as a functional homolog of the diphtheria toxin repressor (DtxR) from Corynebacterium diphtheriae , 1995, Infection and immunity.

[9]  G. Petsko,et al.  Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[10]  J. A. Oguiza,et al.  Molecular cloning, DNA sequence analysis, and characterization of the Corynebacterium diphtheriae dtxR homolog from Brevibacterium lactofermentum , 1995, Journal of bacteriology.

[11]  M. Schmitt,et al.  Cloning, sequence, and footprint analysis of two promoter/operators from Corynebacterium diphtheriae that are regulated by the diphtheria toxin repressor (DtxR) and iron , 1994, Journal of bacteriology.

[12]  J. Murphy,et al.  Cysteine-102 is positioned in the metal binding activation site of the Corynebacterium diphtheriae regulatory element DtxR. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[13]  M. Schmitt,et al.  Analysis of diphtheria toxin repressor‐operator interactions and characterization of a mutant repressor with decreased binding activity for divalent metals , 1993, Molecular microbiology.

[14]  J. Murphy,et al.  Binding of the metalloregulatory protein DtxR to the diphtheria tox operator requires a divalent heavy metal ion and protects the palindromic sequence from DNase I digestion. , 1992, The Journal of biological chemistry.

[15]  J. Murphy,et al.  Specific binding of the diphtheria tox regulatory element DtxR to the tox operator requires divalent heavy metal ions and a 9-base-pair interrupted palindromic sequence. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[16]  J. Murphy,et al.  Molecular cloning and DNA sequence analysis of a diphtheria tox iron-dependent regulatory element (dtxR) from Corynebacterium diphtheriae. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[17]  R. Pictet,et al.  In vivo selected promoter and ribosome binding site up-mutations: Demonstration that the Escherichia coli bla promoter and a Shine-Dalgarno region with low complementarity to the 16 S ribosomal RNA function in Bacillus subtilis , 1989, Molecular and General Genetics MGG.

[18]  C. Verlinde,et al.  Three-dimensional structure of the diphtheria toxin repressor in complex with divalent cation co-repressors. , 1995, Structure.

[19]  G. Stewart,et al.  Differential utilization of Staphylococcus aureus promoter sequences by Escherichia coli and Bacillus subtilis. , 1986, Gene.

[20]  Jeffrey H. Miller.  Experiments in molecular genetics , 1972 .