Antileishmanial activity and evaluation of the mechanism of action of strychnobiflavone flavonoid isolated from Strychnos pseudoquina against Leishmania infantum

[1]  Sarman Singh Changing trends in the epidemiology, clinical presentation, and diagnosis of Leishmania-HIV co-infection in India. , 2014, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

[2]  Raymond Cooper,et al.  Natural Products Sources , 2014 .

[3]  Jaya Lakkakula,et al.  A vision for cyclodextrin nanoparticles in drug delivery systems and pharmaceutical applications. , 2014, Nanomedicine.

[4]  M. D. de Sousa,et al.  Leishmania-HIV Co-infection: Clinical Presentation and Outcomes in an Urban Area in Brazil , 2014, PLoS neglected tropical diseases.

[5]  D. P. Lage,et al.  Novel targeting using nanoparticles: an approach to the development of an effective anti-leishmanial drug-delivery system , 2014, International journal of nanomedicine.

[6]  A. Tempone,et al.  Antimicrobial peptides isolated from Phyllomedusa nordestina (Amphibia) alter the permeability of plasma membrane of Leishmania and Trypanosoma cruzi. , 2013, Experimental parasitology.

[7]  N. Taniwaki,et al.  Lethal action of the nitrothiazolyl-salicylamide derivative nitazoxanide via induction of oxidative stress in Leishmania (L.) infantum. , 2013, Acta tropica.

[8]  Ricardo Obonaga,et al.  Treatment Failure and Miltefosine Susceptibility in Dermal Leishmaniasis Caused by Leishmania Subgenus Viannia Species , 2013, Antimicrobial Agents and Chemotherapy.

[9]  J. D. S. Filho,et al.  Strychnos pseudoquina and Its Purified Compounds Present an Effective In Vitro Antileishmanial Activity , 2013, Evidence-based complementary and alternative medicine : eCAM.

[10]  J. Beijnen,et al.  Increasing failure of miltefosine in the treatment of Kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance. , 2013, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[11]  P. Kaye,et al.  Functional complexity of the Leishmania granuloma and the potential of in silico modeling , 2013, Front. Immun..

[12]  M. Simona,et al.  CD157-extracellular matrix proteins interactions enhance integrin-mediated signalling cascade in monocytes , 2013 .

[13]  J. Beijnen,et al.  Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis. , 2012, The Journal of antimicrobial chemotherapy.

[14]  L. Chow,et al.  Flavonoid dimers as novel, potent antileishmanial agents. , 2012, Journal of medicinal chemistry.

[15]  R. Menna-Barreto,et al.  Mitochondrial damage contribute to epigallocatechin-3-gallate induced death in Leishmania amazonensis. , 2012, Experimental parasitology.

[16]  H. Goto,et al.  Review of the current treatments for leishmaniases. , 2012, Research and reports in tropical medicine.

[17]  J. Cano,et al.  Leishmaniasis Worldwide and Global Estimates of Its Incidence , 2012, PloS one.

[18]  M. N. Melo,et al.  Evaluation of parasitological and immunological parameters of Leishmania chagasi infection in BALB/c mice using different doses and routes of inoculation of parasites , 2012, Parasitology Research.

[19]  M. Santoro,et al.  Leishmanicidal activity of the Agaricus blazei Murill in different Leishmania species. , 2011, Parasitology international.

[20]  L. Gille,et al.  Mitochondria and Trypanosomatids: Targets and Drugs , 2011, Pharmaceutical Research.

[21]  M. Arkin,et al.  A Screen against Leishmania Intracellular Amastigotes: Comparison to a Promastigote Screen and Identification of a Host Cell-Specific Hit , 2011, PLoS neglected tropical diseases.

[22]  E. E. Almeida-Amaral,et al.  Reactive Oxygen Species Production and Mitochondrial Dysfunction Contribute to Quercetin Induced Death in Leishmania amazonensis , 2011, PloS one.

[23]  S. Porwollik,et al.  Analysis of Salmonella enterica Serotype Paratyphi A Gene Expression in the Blood of Bacteremic Patients in Bangladesh , 2010, PLoS Neglected Tropical Diseases.

[24]  S. Castanys,et al.  Tafenoquine, an Antiplasmodial 8-Aminoquinoline, Targets Leishmania Respiratory Complex III and Induces Apoptosis , 2010, Antimicrobial Agents and Chemotherapy.

[25]  S. Krähenbühl,et al.  Drug interactions and adverse events associated with antimycotic drugs used for invasive aspergillosis in hematopoietic SCT , 2010, Bone Marrow Transplantation.

[26]  C. Nakamura,et al.  Evaluation of antileishmanial activity of eupomatenoid-5, a compound isolated from leaves of Piper regnellii var. pallescens. , 2010, Parasitology international.

[27]  Auguste Genovesio,et al.  Antileishmanial High-Throughput Drug Screening Reveals Drug Candidates with New Scaffolds , 2010, PLoS neglected tropical diseases.

[28]  J. Shaw,et al.  New World Leishmaniasis , 2010 .

[29]  S. Croft,et al.  In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent. , 2010, The Journal of antimicrobial chemotherapy.

[30]  Piyali Mukherjee,et al.  Apoptosis-like death in Leishmania donovani promastigotes induced by diospyrin and its ethanolamine derivative. , 2009, International journal of antimicrobial agents.

[31]  W. de Souza,et al.  Particularities of mitochondrial structure in parasitic protists (Apicomplexa and Kinetoplastida). , 2009, The international journal of biochemistry & cell biology.

[32]  Renata L. S. Goncalves,et al.  The effects on Trypanosoma cruzi of novel synthetic naphthoquinones are mediated by mitochondrial dysfunction. , 2009, Free radical biology & medicine.

[33]  Paul Cos,et al.  In Vitro Susceptibilities of Leishmania donovani Promastigote and Amastigote Stages to Antileishmanial Reference Drugs: Practical Relevance of Stage-Specific Differences , 2009, Antimicrobial Agents and Chemotherapy.

[34]  Jesús Díaz,et al.  Antileishmaniasis activity of flavonoids from Consolida oliveriana. , 2009, Journal of natural products.

[35]  P. Maulik,et al.  Peganine hydrochloride dihydrate an orally active antileishmanial agent. , 2009, Bioorganic & medicinal chemistry letters.

[36]  G. L. Deliliers,et al.  Retrospective evaluation of amphotericin B deoxycholate toxicity in a single centre series of haematopoietic stem cell transplantation recipients. , 2009, Journal of Antimicrobial Chemotherapy.

[37]  S. Sundar,et al.  Visceral Leishmaniasis Elimination Programme in India, Bangladesh, and Nepal: Reshaping the Case Finding/Case Management Strategy , 2009, PLoS neglected tropical diseases.

[38]  S. Bischoff Quercetin: potentials in the prevention and therapy of disease , 2008, Current opinion in clinical nutrition and metabolic care.

[39]  H. Castro,et al.  Leishmaniasis treatment—a challenge that remains: a review , 2008, Parasitology Research.

[40]  M. Butler Natural products to drugs: natural product-derived compounds in clinical trials. , 2005, Natural product reports.

[41]  R. Peeling,et al.  Visceral leishmaniasis: what are the needs for diagnosis, treatment and control? , 2007, Nature Reviews Microbiology.

[42]  A. Vercesi,et al.  Sterol methenyl transferase inhibitors alter the ultrastructure and function of the Leishmania amazonensis mitochondrion leading to potent growth inhibition. , 2007, Protist.

[43]  S. Robledo,et al.  Antiprotozoal and cytotoxic activities in vitro of Colombian Annonaceae. , 2007, Journal of ethnopharmacology.

[44]  P. Parola,et al.  Cutaneous leishmaniasis treatment. , 2007, Travel medicine and infectious disease.

[45]  Shyam Sundar,et al.  Liposomal amphotericin B for the treatment of visceral leishmaniasis. , 2006, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[46]  C. Nakamura,et al.  Antileishmanial activity of Eugenol-rich essential oil from Ocimum gratissimum. , 2006, Parasitology international.

[47]  J. Mead,et al.  Antiparasitic activity of flavonoids and isoflavones against Cryptosporidium parvum and Encephalitozoon intestinalis. , 2006, FEMS microbiology letters.

[48]  C. Shaha,et al.  Mechanism of metalloid-induced death in Leishmania spp.: role of iron, reactive oxygen species, Ca2+, and glutathione. , 2006, Free radical biology & medicine.

[49]  J. Barbosa-Filho,et al.  A review of natural products with antileishmanial activity. , 2005, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[50]  W. de Souza,et al.  Antileishmanial Activity of Parthenolide, a Sesquiterpene Lactone Isolated from Tanacetum parthenium , 2005, Antimicrobial Agents and Chemotherapy.

[51]  A. Henriques-Pons,et al.  Effect of the lysophospholipid analogues edelfosine, ilmofosine and miltefosine against Leishmania amazonensis. , 2004, The Journal of antimicrobial chemotherapy.

[52]  L. Angenot,et al.  About the toxicity of some Strychnos species and their alkaloids. , 2004, Toxicon : official journal of the International Society on Toxinology.

[53]  R. Spinelli,et al.  In vitro assays for evaluation of drug activity against Leishmania spp. , 2004, Research in microbiology.

[54]  D. Malvy,et al.  Quercetin Induces Apoptosis of Trypanosoma brucei gambiense and Decreases the Proinflammatory Response of Human Macrophages , 2004, Antimicrobial Agents and Chemotherapy.

[55]  S. Sundar,et al.  Efficacy and tolerability of miltefosine for childhood visceral leishmaniasis in India. , 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[56]  J. Phillipson,et al.  Antimalarial activity of Artemisia annua flavonoids from whole plants and cell cultures , 1992, Plant Cell Reports.

[57]  S. Croft,et al.  Leishmaniasis--current chemotherapy and recent advances in the search for novel drugs. , 2003, Trends in parasitology.

[58]  R. Verpoorte,et al.  Alkaloids and a pimarane diterpenoid from Strychnos vanprukii. , 2003, Phytochemistry.

[59]  J. Stehmann,et al.  Antimalarial activity of Cinchona-like plants used to treat fever and malaria in Brazil. , 2003, Journal of ethnopharmacology.

[60]  G. Matlashewski,et al.  Immune Responses Induced by the Leishmania (Leishmania) donovani A2 Antigen, but Not by the LACK Antigen, Are Protective against Experimental Leishmania (Leishmania) amazonensis Infection , 2003, Infection and Immunity.

[61]  David J Newman,et al.  Natural products as sources of new drugs over the period 1981-2002. , 2003, Journal of natural products.

[62]  E. S. Coimbra,et al.  Characterization and cytochemical localization of an ATP diphosphohydrolase from Leishmania amazonensis promastigotes , 2002, Parasitology.

[63]  S. Croft,et al.  Sensitivities of Leishmania species to hexadecylphosphocholine (miltefosine), ET-18-OCH(3) (edelfosine) and amphotericin B. , 2002, Acta tropica.

[64]  H. Murray Tissue granuloma structure‐function in experimental visceral leishmaniasis , 2001, International journal of experimental pathology.

[65]  M. Attias,et al.  Antileishmanial Activity of an Indole Alkaloid fromPeschiera australis , 2001, Antimicrobial Agents and Chemotherapy.

[66]  S. Croft,et al.  In Vivo Monitoring of Intracellular ATP Levels inLeishmania donovani Promastigotes as a Rapid Method To Screen Drugs Targeting Bioenergetic Metabolism , 2001, Antimicrobial Agents and Chemotherapy.

[67]  R. Ashford,et al.  The leishmaniases as emerging and reemerging zoonoses. , 2000, International journal for parasitology.

[68]  D. Haburchak,et al.  Topley and Wilson's Microbiology and Microbial Infections , 1999 .

[69]  J. M. Pérez-Victoria,et al.  Correlation between the affinity of flavonoids binding to the cytosolic site of Leishmania tropica multidrug transporter and their efficiency to revert parasite resistance to daunomycin. , 1999, Biochemistry.

[70]  D. Andreu,et al.  The plasma membrane of Leishmania donovani promastigotes is the main target for CA(1-8)M(1-18), a synthetic cecropin A-melittin hybrid peptide. , 1998, The Biochemical journal.

[71]  Max Sussman,et al.  Topley and Wilson's Microbiology and Microbial infections , 1998 .

[72]  R. López-Vélez,et al.  Leishmania and human immunodeficiency virus coinfection: the first 10 years , 1997, Clinical microbiology reviews.

[73]  J. Engel,et al.  Leishmania donovani: long-term culture of axenic amastigotes at 37 degrees C. , 1991, Experimental parasitology.

[74]  R. Lainson The American leishmaniases: some observations on their ecology and epidemiology. , 1983, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[75]  G. L. Cruz,et al.  Dicionário das plantas úteis do Brasil , 1979 .

[76]  M. P. Corrêa Diccionário das plantas úteis do Brasil e das exóticas cultivadas , 1931 .