Antimicrobial activities of marine cyanobacteria is olated from mangrove environment of south east coast of India

Cyanobacteria were isolated from the intertidal zon e of three different mangrove environment Pichavaram (11° 27' N 79° 47' E), Parangipettai (11° 29' N 79° 47' E) and Mudasal Odai (11° 28' N 79° 46' E) on southeast coast of India. Seven cyanobacteria were extracted in methanol, and a mix ture of chloroform, methanol and water (1:2:0.8), and tested for antimicrobial activ ity against nine human bacterial pathogens (Bacillus subtilis , Escherichia coli , Vibrio parahaemolyticus , Proteus vulgaris , Pseudomonas aeruginosa , Salmonella typhi , Shigella flexneri , Staphylococcus aureus and Vibrio cholerae), five plant fungal pathogens (Colletotrichum falcatum , Fusarium solani , Helminthosporium oryzae , Pyricularia oryzae and Rhizoctonia solani ) and four animal fungal pathogens ( Aspergillus flavus , A. fumigates , Candida albicans and Rhizopus species). Except Oscillatoria cortiana methanol extract, the cyanobacterial species exhibited antibacterial activity. Human bacterial pathogens except Pseudomonas aeruginosa and Vibrio cholerae , were inhibited. Except Synechocystis salina methanol extract, the cyanobacterial species showed antifungal activity. Plant fungal pathogens other than Colletotrichum falcatum and Fusarium solani were inhibited. Human fungal pathogens except Aspergillus flavus were inhibited. The maximum antibacterial inhibiti on zone of 9 mm was observed in Oscillatoria willei against Salmonella typhi . The maximum antifungal activity with inhibition zone of 5 mm was observed with Oscillatoria salina methanol extract against Fusarium solani , Phormidium tenue methanol extract and Rhizoctonia solani .