Isolated Choroid Plexus Infarction Presenting as Psychomotor Slowing

332 A 70-year-old right-handed woman with 9 years of education was brought to our clinic by her husband, who reported that over the past 20 days, the patient had experienced a visible slowing of physical and emotional reactions. She had a history of hypertension and hyperlipidemia. The patient’s husband reported that she did not have any history of depression or headache and had a fairly good memory. Furthermore, there was no preceding history of head trauma, encephalitis, antipsychotic or antiemetic medication use, or exposure to toxic substances. However, she was noticeably slower in performing activities which normally would require little thought or effort such as responding to simple questions, preparing meals and clearing dishes from the table, or returning phone calls. Her mini–mental state examination score was 28/30 (two points lost on attention and calculation task). Neuropsychological tests revealed an impairment in frontal/executive function, but not of memory, language, and visuospatial functions. The patient’s cranial nerves were intact. Motor examination revealed normal muscle strength and tone, along with normal deep tendon reflexes. Sensory examination results were also normal for all modalities, and the Babinski sign was not elicited. In addition, abnormal behaviors were not seen on the neuropsychiatric inventory questionnaire. Her score on the Geriatric Depression Scale was 2/30.