Intra-individual variation in serum C-reactive protein over 4 years: an implication for epidemiologie studies Elizabeth A. PlatzSiobhan SutcliffeAngelo M. De Marzo • Charles G. DrakeNader RifaiAnn W. HsingAshraful Hoque •

Background Data on long-term intra-individual variability in high-sensitivity C-reactive protein (hsCRP) are needed to determine whether one measurement adequately reflects usual levels in prospective studies of on the etiology of cancer and other chronic diseases; when not reflective, the ability to statistically detect modest to moderate associations is reduced. The authors estimated

[1]  P. Ridker,et al.  Tracking of high-sensitivity C-reactive protein after an initially elevated concentration: the JUPITER Study. , 2009, Clinical chemistry.

[2]  A. Jenkins,et al.  C-reactive protein concentrations are very high and more stable over time than the traditional vascular risk factors total cholesterol and systolic blood pressure in an Australian aboriginal cohort. , 2009, Clinical chemistry.

[3]  T. Erlinger,et al.  C‐reactive protein and colorectal cancer risk: A systematic review of prospective studies , 2008, International journal of cancer.

[4]  X. Shu,et al.  Intra-individual Variation of Plasma Adipokine Levels and Utility of Single Measurement of These Biomarkers in Population-Based Studies , 2007, Cancer Epidemiology Biomarkers & Prevention.

[5]  S. Kagamimori,et al.  Intra-individual variability of high-sensitivity C-reactive protein: age-related variations over time in Japanese subjects. , 2006, Circulation journal : official journal of the Japanese Circulation Society.

[6]  H. Boshuizen,et al.  Reliability of biomarkers of iron status, blood lipids, oxidative stress, vitamin D, C-reactive protein and fructosamine in two Dutch cohorts , 2006, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

[7]  Vilmundur Gudnason,et al.  C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. , 2004, The New England journal of medicine.

[8]  W. Koenig,et al.  Refinement of the association of serum C-reactive protein concentration and coronary heart disease risk by correction for within-subject variation over time: the MONICA Augsburg studies, 1984 and 1987. , 2003, American journal of epidemiology.

[9]  Michael M Lieber,et al.  Journal Review , 2003, International Society of Hair Restoration Surgery.

[10]  P. Ridker,et al.  Variability and classification accuracy of serial high-sensitivity C-reactive protein measurements in healthy adults. , 2001, Clinical chemistry.

[11]  N Rifai,et al.  High-sensitivity C-reactive protein: a novel and promising marker of coronary heart disease. , 2001, Clinical chemistry.

[12]  K. Kario,et al.  Five-year intra-individual variability in C-reactive protein levels in a Japanese population-based study: the Jichi Medical School Cohort Study at Yamato, 1993-1998. , 2000, Japanese circulation journal.

[13]  M. Pfeffer,et al.  Long-Term Effects of Pravastatin on Plasma Concentration of C-reactive Protein , 1999 .

[14]  L. Kuller,et al.  Analytical and biologic variability in measures of hemostasis, fibrinolysis, and inflammation: assessment and implications for epidemiology. , 1999, American journal of epidemiology.

[15]  R. Tracy,et al.  Variability in the measurement of C-reactive protein in healthy subjects: implications for reference intervals and epidemiological applications. , 1997, Clinical chemistry.

[16]  C. Kluft,et al.  Interindividual and intraindividual variability in plasma fibrinogen, TPA antigen, PAI activity, and CRP in healthy, young volunteers and patients with angina pectoris. , 1996, Arteriosclerosis, thrombosis, and vascular biology.

[17]  C. Fraser,et al.  Biological Variation of Acute Phase Proteins , 1993, Annals of clinical biochemistry.

[18]  B Rosner,et al.  Correction of logistic regression relative risk estimates and confidence intervals for random within-person measurement error. , 1992, American journal of epidemiology.