Signalling pathway for RKIP and Let‐7 regulates and predicts metastatic breast cancer

[1]  Israel Steinfeld,et al.  miRNA-mRNA Integrated Analysis Reveals Roles for miRNAs in Primary Breast Tumors , 2011, PloS one.

[2]  Udaya B. Kogalur,et al.  High-Dimensional Variable Selection for Survival Data , 2010 .

[3]  Marc Ladanyi,et al.  WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis , 2009, Cell.

[4]  A. Chambers,et al.  MDA-MB-435 and M14 cell lines: identical but not M14 melanoma? , 2009, Cancer research.

[5]  Yan Gao,et al.  Effects of Raf Kinase Inhibitor Protein Expression on Metastasis and Progression of Human Breast Cancer , 2009, Molecular Cancer Research.

[6]  S. Dangi‐Garimella,et al.  Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let‐7 , 2009, The EMBO journal.

[7]  Charles M. Perou,et al.  Triple-Negative Breast Cancer: Risk Factors to Potential Targets , 2008, Clinical Cancer Research.

[8]  T. Noda,et al.  Bach1 inhibits oxidative stress–induced cellular senescence by impeding p53 function on chromatin , 2008, Nature Structural &Molecular Biology.

[9]  Hemant Ishwaran,et al.  An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer , 2008, Proceedings of the National Academy of Sciences.

[10]  R. Weinberg,et al.  Systemic Endocrine Instigation of Indolent Tumor Growth Requires Osteopontin , 2008, Cell.

[11]  R. Tavares,et al.  Inverse Association between Raf Kinase Inhibitory Protein and Signal Transducers and Activators of Transcription 3 Expression in Gastric Adenocarcinoma Patients: Implications for Clinical Outcome , 2008, Clinical Cancer Research.

[12]  C. Burge,et al.  Identification of let-7-regulated oncofetal genes. , 2008, Cancer research.

[13]  M. Rosner,et al.  Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor , 2008, Cell Research.

[14]  D. Welch,et al.  Metastasis Suppressors and the Tumor Microenvironment , 2008, Cancer Microenvironment.

[15]  Leonard D. Goldstein,et al.  MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype , 2007, Genome Biology.

[16]  Anindya Dutta,et al.  The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. , 2007, Genes & development.

[17]  H. Ishwaran,et al.  Lung metastasis genes couple breast tumor size and metastatic spread , 2007, Proceedings of the National Academy of Sciences.

[18]  Paula D. Bos,et al.  Mediators of vascular remodelling co-opted for sequential steps in lung metastasis , 2007, Nature.

[19]  G. Sherlock,et al.  The prognostic role of a gene signature from tumorigenic breast-cancer cells. , 2007, The New England journal of medicine.

[20]  J. Massagué.  Sorting out breast-cancer gene signatures. , 2007, The New England journal of medicine.

[21]  W. Kolch,et al.  Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[22]  Miao Sun,et al.  MicroRNA and cancer: Current status and prospective , 2006, International journal of cancer.

[23]  Wen-Lin Kuo,et al.  A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. , 2006, Cancer cell.

[24]  O. Kawanami,et al.  Growth-suppressive function of phosphatidylethanolamine-binding protein in anaplastic thyroid cancer. , 2006, Anticancer research.

[25]  R. Tibshirani,et al.  On testing the significance of sets of genes , 2006, math/0610667.

[26]  U. Klein,et al.  Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint. , 2006, Molecular cell.

[27]  Hongyu Zhao,et al.  Pathway analysis using random forests classification and regression , 2006, Bioinform..

[28]  Peter J. Keller,et al.  Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer , 2006, The Prostate.

[29]  Jeffrey T. Chang,et al.  Oncogenic pathway signatures in human cancers as a guide to targeted therapies , 2006, Nature.

[30]  A. Hatzigeorgiou,et al.  TarBase: A comprehensive database of experimentally supported animal microRNA targets. , 2005, RNA.

[31]  Karin Oien,et al.  Reduction of Raf-1 Kinase Inhibitor Protein Expression Correlates with Breast Cancer Metastasis , 2005, Clinical Cancer Research.

[32]  Andy J. Minn,et al.  Genes that mediate breast cancer metastasis to lung , 2005, Nature.

[33]  M. Rosner,et al.  Raf Kinase Inhibitory Protein Regulates Raf-1 but Not B-Raf Kinase Activation* , 2005, Journal of Biological Chemistry.

[34]  K. Gunsalus,et al.  Combinatorial microRNA target predictions , 2005, Nature Genetics.

[35]  F. Slack,et al.  RAS Is Regulated by the let-7 MicroRNA Family , 2005, Cell.

[36]  Howard Y. Chang,et al.  Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[37]  Cameron S. Osborne,et al.  Molecular Determinants of NOTCH4 Transcription in Vascular Endothelium , 2005, Molecular and Cellular Biology.

[38]  C. Burge,et al.  Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets , 2005, Cell.

[39]  Jean YH Yang,et al.  Bioconductor: open software development for computational biology and bioinformatics , 2004, Genome Biology.

[40]  A. Bosserhoff,et al.  Reduction in Raf Kinase Inhibitor Protein Expression Is Associated with Increased Ras-Extracellular Signal-Regulated Kinase Signaling in Melanoma Cell Lines , 2004, Cancer Research.

[41]  Benjamin M. Bolstad,et al.  affy - analysis of Affymetrix GeneChip data at the probe level , 2004, Bioinform..

[42]  J. D. Engel,et al.  Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique , 2004, Genes to cells : devoted to molecular & cellular mechanisms.

[43]  K. Lorenz,et al.  Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2 , 2003, Nature.

[44]  C. Cordon-Cardo,et al.  A multigenic program mediating breast cancer metastasis to bone. , 2003, Cancer cell.

[45]  E. Eves,et al.  Activation of Raf-1 Signaling by Protein Kinase C through a Mechanism Involving Raf Kinase Inhibitory Protein* , 2003, The Journal of Biological Chemistry.

[46]  Yudong D. He,et al.  Gene expression profiling predicts clinical outcome of breast cancer , 2002, Nature.

[47]  W. Kolch,et al.  Raf Kinase Inhibitor Protein Interacts with NF-κB-Inducing Kinase and TAK1 and Inhibits NF-κB Activation , 2001, Molecular and Cellular Biology.

[48]  W. Kolch,et al.  Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP , 1999, Nature.

[49]  M. Rosner,et al.  Raf kinase inhibitory protein (RKIP): a physiological regulator and future therapeutic target. , 2008, Expert opinion on therapeutic targets.

[50]  Andy Liaw,et al.  Classification and Regression by randomForest , 2007 .

[51]  Chris Cheadle,et al.  Application of z-score transformation to Affymetrix data. , 2003, Applied bioinformatics.

[52]  M. Rubin,et al.  Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis. , 2003, Journal of the National Cancer Institute.

[53]  W. Kolch,et al.  Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation. , 2001, Molecular and cellular biology.

[54]  David P. Bartel,et al.  Supporting Online Material Materials and Methods Fig. S1 Tables S1 and S2 References Database S1 Disrupting the Pairing between Let-7 and Hmga2 Enhances Oncogenic Transformation , 2022 .