Insulin-like growth factor 1 can promote the osteogenic differentiation and osteogenesis of stem cells from apical papilla.

[1]  A. Iglesias-Linares,et al.  Revascularization of immature permanent teeth with apical periodontitis. , 2014, International endodontic journal.

[2]  V. Laizé,et al.  Proliferative and mineralogenic effects of insulin, IGF-1, and vanadate in fish osteoblast-like cells , 2011, Journal of Bone and Mineral Metabolism.

[3]  Ming Yan,et al.  Dentinogenic capacity: immature root papilla stem cells versus mature root pulp stem cells , 2011, Biology of the cell.

[4]  Q. Lian,et al.  Morphological and proteomic analysis of early stage of osteoblast differentiation in osteoblastic progenitor cells. , 2010, Experimental cell research.

[5]  W. Götz,et al.  IGF-I, IGF-IR and IRS1 expression as an early reaction of PDL cells to experimental tooth movement in the rat. , 2010, Archives of oral biology.

[6]  R. Tuan,et al.  Stem/progenitor cell-mediated de novo regeneration of dental pulp with newly deposited continuous layer of dentin in an in vivo model. , 2010, Tissue engineering. Part A.

[7]  M. Tekin,et al.  Modulation of Fgf3 dosage in mouse and men mirrors evolution of mammalian dentition , 2009, Proceedings of the National Academy of Sciences.

[8]  R. T. Ballock,et al.  Thyroid Hormone-Mediated Growth and Differentiation of Growth Plate Chondrocytes Involves IGF-1 Modulation of β-Catenin Signaling , 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[9]  J. Deschner,et al.  Regulatory effects of biomechanical strain on the insulin-like growth factor system in human periodontal cells. , 2009, Journal of biomechanics.

[10]  E. Canalis.  Growth factor control of bone mass , 2009, Journal of cellular biochemistry.

[11]  J. Jansen,et al.  Mineralized Tissue Formation by BMP2-transfected Pulp Stem Cells , 2009, Journal of dental research.

[12]  Yin Xiao,et al.  Stem cell regulatory gene expression in human adult dental pulp and periodontal ligament cells undergoing odontogenic/osteogenic differentiation. , 2009, Journal of endodontics.

[13]  Y. H. Wang,et al.  Runx2, Osx, and Dspp in Tooth Development , 2009, Journal of dental research.

[14]  S. Gronthos,et al.  Mesenchymal Stem Cells Derived from Dental Tissues vs. Those from Other Sources: Their Biology and Role in Regenerative Medicine , 2009, Journal of dental research.

[15]  B. de Crombrugghe,et al.  Positive Regulation of Adult Bone Formation by Osteoblast‐Specific Transcription Factor Osterix , 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[16]  Guoping Fan,et al.  BCOR regulates mesenchymal stem cell function by epigenetic mechanisms , 2009, Nature Cell Biology.

[17]  A. Tucker,et al.  Current knowledge of tooth development: patterning and mineralization of the murine dentition , 2009, Journal of anatomy.

[18]  Ganzhen Deng,et al.  The stimulatory effect of insulin-like growth factor-1 on the proliferation, differentiation, and mineralisation of osteoblastic cells from Holstein cattle. , 2009, Veterinary journal.

[19]  Young-Sool Hah,et al.  In vitro osteogenic differentiation of cultured human dental papilla-derived cells. , 2009, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[20]  C. Shin,et al.  A Novel Mutation in the DSPP Gene Associated with Dentinogenesis Imperfecta Type II , 2009, Journal of dental research.

[21]  F. De Luca,et al.  Stimulatory Effects of Insulin-like Growth Factor-I on Growth Plate Chondrogenesis Are Mediated by Nuclear Factor-κB p65* , 2008, Journal of Biological Chemistry.

[22]  P. Ye,et al.  IGF-I improved bone mineral density and body composition of weaver mutant mice. , 2008, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[23]  D. McKnight,et al.  Overlapping DSPP Mutations Cause Dentin Dysplasia and Dentinogenesis Imperfecta , 2008, Journal of dental research.

[24]  Mia M. Thi,et al.  IGF-I regulates tight-junction protein claudin-1 during differentiation of osteoblast-like MC3T3-E1 cells via a MAP-kinase pathway , 2008, Cell and Tissue Research.

[25]  S. Rokutanda,et al.  Inhibition of the terminal differentiation of odontoblasts and their transdifferentiation into osteoblasts in Runx2 transgenic mice. , 2008, Archives of histology and cytology.

[26]  T. Amagasa,et al.  Hard tissue regeneration capacity of apical pulp derived cells (APDCs) from human tooth with immature apex. , 2008, Biochemical and biophysical research communications.

[27]  S. Shi,et al.  The hidden treasure in apical papilla: the potential role in pulp/dentin regeneration and bioroot engineering. , 2008, Journal of endodontics.

[28]  R. Tuan,et al.  Characterization of the apical papilla and its residing stem cells from human immature permanent teeth: a pilot study. , 2008, Journal of endodontics.

[29]  E. Schwarz,et al.  Osterix/Sp7 regulates mesenchymal stem cell mediated endochondral ossification , 2008, Journal of cellular physiology.

[30]  H. Munoz,et al.  Variation in the expression of insulin-like growth factor-1 in human pulp tissue according to the root-development stage. , 2007, Journal of endodontics.

[31]  F. Giorgino,et al.  The IGF-I signaling pathway. , 2007, Current pharmaceutical design.

[32]  M. Zeichner‐David,et al.  Establishment and characterization of an immortomouse‐derived odontoblast‐like cell line to evaluate the effect of insulin‐like growth factors on odontoblast differentiation , 2007, Journal of cellular biochemistry.

[33]  Cun-Yu Wang,et al.  Mesenchymal Stem Cell-Mediated Functional Tooth Regeneration in Swine , 2006, PloS one.

[34]  Toshihisa Komori,et al.  Regulation of osteoblast differentiation by transcription factors , 2006, Journal of cellular biochemistry.

[35]  G. T. Huang,et al.  Immature teeth with periradicular periodontitis or abscess undergoing apexogenesis: a paradigm shift. , 2006, Journal of endodontics.

[36]  I. Thesleff,et al.  Different Roles of Runx2 During Early Neural Crest–Derived Bone and Tooth Development , 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[37]  S. Takai,et al.  Involvement of p44/p42 MAP kinase in insulin-like growth factor-I-induced alkaline phosphatase activity in osteoblast-like-MC3T3-E1 cells , 2006, Molecular and Cellular Endocrinology.

[38]  C. Rosen,et al.  Postnatal growth and bone mass in mice with IGF-I haploinsufficiency. , 2006, Bone.

[39]  K. Koyano,et al.  Type II/III Runx2/Cbfa1 is required for tooth germ development. , 2006, Bone.

[40]  O. MacDougald,et al.  Regulation of bone mass by Wnt signaling. , 2006, The Journal of clinical investigation.

[41]  J. B. Alves,et al.  Fibroblast growth factor 9: cloning and immunolocalisation during tooth development in Didelphis albiventris. , 2006, Archives of oral biology.

[42]  S. Oida,et al.  Gene Expression and Localization of Insulin-like Growth Factors and Their Receptors throughout Amelogenesis in Rat Incisors , 2006, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[43]  Ayse B. Celil,et al.  BMP-2 and Insulin-like Growth Factor-I Mediate Osterix (Osx) Expression in Human Mesenchymal Stem Cells via the MAPK and Protein Kinase D Signaling Pathways* , 2005, Journal of Biological Chemistry.

[44]  Yimin Wu,et al.  Differential Regulation of Dentin Sialophosphoprotein Expression by Runx2 during Odontoblast Cytodifferentiation* , 2005, Journal of Biological Chemistry.

[45]  S. Takai,et al.  Possible Involvement of Phosphatidylinositol 3-Kinase/Akt Pathway in Insulin-like Growth Factor-I-induced Alkaline Phosphatase Activity in Osteoblasts , 2005, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[46]  M. Tabata,et al.  Insulin-like growth factor-I stimulates cell proliferation in the outer layer of Hertwig’s epithelial root sheath and elongation of the tooth root in mouse molars in vitro , 2005, Cell and Tissue Research.

[47]  M. Zeichner‐David,et al.  IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. , 2005, Archives of oral biology.

[48]  N. Kanbur,et al.  The relationships between pubertal development, IGF-1 axis, and bone formation in healthy adolescents , 2004, Journal of Bone and Mineral Metabolism.

[49]  H. Munoz,et al.  Expression of insulin-like growth factor-1 receptor in human pulp tissue. , 2004, Journal of endodontics.

[50]  H. Werner,et al.  The Emerging Role of the Insulin-like Growth Factors in Oral Biology , 2004, Journal of dental research.

[51]  A. Passaniti,et al.  Insulin-like Growth Factor-1 Regulates Endogenous RUNX2 Activity in Endothelial Cells through a Phosphatidylinositol 3-Kinase/ERK-dependent and Akt-independent Signaling Pathway* , 2004, Journal of Biological Chemistry.

[52]  O. Baba,et al.  Post-translational modifications of sibling proteins and their roles in osteogenesis and dentinogenesis. , 2004, Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists.

[53]  M. Trope,et al.  Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol? , 2004, Journal of endodontics.

[54]  M. McKee,et al.  Extracellular Matrix Proteins and the Dynamics of Dentin Formation , 2002, Connective tissue research.

[55]  P. Roholl,et al.  Expression of insulin‐like growth factor 1 in sarcomas , 1990, Histopathology.

[56]  J. B. Alves,et al.  Role of BMP-4 during tooth development in a model with complete dentition. , 2008, Archives of oral biology.

[57]  W. Young,et al.  Growth hormone and insulin-like growth factor-I in odontogenesis. , 1995, The International journal of developmental biology.

[58]  J. Cornish,et al.  Mitogen-Activated Protein Kinase Signaling Pathways Subserve the Mitogenic and Antiapoptotic Actions of , 2022 .