Synthesis of N-substituted benzo[c][1,7]- and benzo[c][1,8] phenanthrolin-(5H)-6-ones through a Pd-mediated Suzuki–Miyaura heteroaryl-aryl coupling reaction
暂无分享,去创建一个
[1] Y. Pommier. DNA topoisomerase I inhibitors: chemistry, biology, and interfacial inhibition. , 2009, Chemical reviews.
[2] C. So,et al. Palladium-indolylphosphine-catalyzed Hiyama cross-coupling of aryl mesylates. , 2009, Organic letters.
[3] V. Bourgarel-Rey,et al. Cascade synthesis of polyoxygenated 6H,11H-[2]benzopyrano-[4,3-c][1]benzopyran-11-ones. , 2007, The Journal of organic chemistry.
[4] Y. Pommier. Topoisomerase I inhibitors: camptothecins and beyond , 2006, Nature Reviews Cancer.
[5] Soizic Prado,et al. Synthesis of benzo[c][1,8]phenanthrolin-6-one through cyclization of N-(isoquinol-5-yl)-2-bromo-benzamide derivatives , 2006 .
[6] D. Tanner,et al. Comparative study of the Kumada, Negishi, Stille, and Suzuki-Miyaura reactions in the synthesis of the indole alkaloids hippadine and pratosine. , 2006, The Journal of organic chemistry.
[7] E. LaVoie,et al. Esters and amides of 2,3-dimethoxy-8,9-methylenedioxy-benzo[i]phenanthridine-12-carboxylic acid: potent cytotoxic and topoisomerase I-targeting agents. , 2005, Bioorganic & Medicinal Chemistry.
[8] Y. Pommier,et al. Synthesis and anticancer activity of simplified indenoisoquinoline topoisomerase I inhibitors lacking substituents on the aromatic rings. , 2004, Journal of medicinal chemistry.
[9] R. Mailman,et al. Synthesis and SAR exploration of dinapsoline analogues. , 2004, Bioorganic & medicinal chemistry.
[10] Peter J Houghton,et al. Characterization of ARC-111 as a novel topoisomerase I-targeting anticancer drug. , 2003, Cancer research.
[11] Sambasivarao Kotha,et al. Recent applications of the Suzuki–Miyaura cross-coupling reaction in organic synthesis , 2002 .
[12] A. Ray,et al. Diaza- and triazachrysenes: potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435. , 2002, Bioorganic & medicinal chemistry letters.
[13] J. Zhang,et al. Synthesis of substituted 5[H]phenanthridin-6-ones as potent poly(ADP-ribose)polymerase-1 (PARP1) inhibitors. , 2001, Bioorganic & medicinal chemistry letters.
[14] Watanabe,et al. Palladium-catalyzed borylation of aryl halides or triflates with dialkoxyborane: A novel and facile synthetic route to arylboronates , 2000, The Journal of organic chemistry.
[15] A. Mckillop,et al. A versatile synthesis of fully aromatic benzo[c]phenanthridine alkaloids , 1998 .
[16] C. Cadilhac,et al. Convenient synthesis of aromatic thiols from phenols , 1996 .
[17] Norio Miyaura,et al. Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds , 1995 .
[18] C. Ling,et al. MODELS FOR INTRAMOLECULAR EXCHANGE IN ORGANIC PI -CONJUGATED OPEN-SHELL SYSTEMS : 3-NITRENOPHENYL AND 4-NITRENOPHENYL UNITS CONNECTED BY 2,5-FURANDIYL , 2,5-THIOPHENEDIYL, AND 2,5-PYRROLEDIYL NONALTERNANT EXCHANGE LINKERS , 1994 .
[19] M. Banwell,et al. Convergent Routes to the [1,3]Dioxolo[4,5-j]phenanthridin-6(5H)-one and 2,3,4,4a-Tetrahydro[1,3]dioxolo[4,5-j]phenanthridin-6(5H)-one Nuclei. Application to Syntheses of the Amaryllidaceae Alkaloids Crinasiadine, N-Methylcrinasiadine and Trisphaeridine , 1994 .
[20] J. Riou,et al. Synthesis and evaluation of new 6-amino-substituted benzo[c]phenanthridine derivatives. , 1993, Journal of medicinal chemistry.
[21] S. Gronowitz,et al. The first synthesis of thieno[c]isoquinolines and an improved synthesis of phenanthridine and thieno[c]quinolines through pd(0) catalyzed coupling of ortho‐formylarylboronic acids with functionalized aryl halides , 1989 .
[22] V. Snieckus,et al. The directed metalation connection to aryl-aryl cross coupling.Regiospecific synthesis of phenanthridines, phenanthridinones and the biphenyl alkaloid ismine , 1988 .
[23] A. Echavarren,et al. Palladium-catalyzed coupling of aryl triflates with organostannanes , 1987 .
[24] A. Sekiguchi,et al. Germathiirane intermediate from the reaction of germylene with thioketones , 1985 .
[25] R. Miller,et al. Synthesis of isoquinolines from indenes , 1980 .
[26] W. E. Cass,et al. Derivatives of Aminoisoquinolines1 , 1942 .