LegislationConcerningChemical Carcinogensin Several IndustrializedCountriesâ

Summary A survey was carried out on legislation in 14 industrialized countries relating to the prevention of occupational can cens.Two types of legislation were considered in particular: that dealing specifically with chemical carcinogens in the working environment, and that relating to compensation for occupational cancers. The survey revealed that legislation prohibiting the manufacture of chemicals known to be car cinogenic in humans or known to represent a possible cancer hazard to humans exists only in a limited number of the 14 countries considered and does not cover the same chemicals in each country. Legislation concerning mone tary compensation is more common in these countries than is legislation providing for primary prevention. There are two fundamentaldeficienciesin eventhe more comprehen sive legislation. First, some chemicals for which carcino genicity in humans has been proved are still produced in large quantities and are not covered by legislation. Second, the criteria used to determine which chemicals may be hazardous to humans when only experimental evidence of cancinogenicity exists are overexclusive, while the allowed concentrations of some of the chemicals recognized as possibly hazardous to humans appear to be very high.

[1]  L Tomatis,et al.  The predictive value of mouse liver tumour induction in carcinogenicity testing—a literature survey , 1973, International journal of cancer.

[2]  U. Saffiotti Editorial: Comments on the scientific basis for the "Delaney Clause". , 1973, Preventive medicine.

[3]  Pamukcu Am Tumours of the urinary bladder. , 1974 .

[4]  P. Cole,et al.  Occupation and cancer of the lower urinary tract , 1972, Cancer.

[5]  S. Epstein,et al.  Environmental determinants of human cancer. , 1974, Cancer research.

[6]  W. Hueper Experimental production of bladder tumors in dogs by administration of beta-naphthylamine. , 1938 .

[7]  L. Tomatis THE IARC PROGRAM ON THE EVALUATION OF THE CARCINOGENIC RISK OF CHEMICALS TO MAN , 1976, Annals of the New York Academy of Sciences.

[8]  R. Hoover,et al.  Tumors of the urinary bladder: an analysis of the occupations of 1,030 patients in Leeds, England. , 1970, Journal of the National Cancer Institute.

[9]  R. Case Tumours of the urinary tract as an occupational disease in several industries. , 1966, Annals of the Royal College of Surgeons of England.

[10]  J. GuijosaPenus,et al.  [Prevention of cancer]. , 1954, Boletin cultural e informativo - Consejo General de Colegios Medicos de Espana.

[11]  A. Ciocco,et al.  An epidemiological approach to the rubber industry. A study based on departmental experience. , 1968, Journal of occupational medicine. : official publication of the Industrial Medical Association.