Engineered allogeneic mesenchymal stem cells repair femoral segmental defect in rats

[1]  D. Butler,et al.  In vitro characterization of mesenchymal stem cell-seeded collagen scaffolds for tendon repair: effects of initial seeding density on contraction kinetics. , 2000, Journal of biomedical materials research.

[2]  F. Dumont.  FK506, an immunosuppressant targeting calcineurin function. , 2000, Current medicinal chemistry.

[3]  R Müller,et al.  Genetic Regulation of Cortical and Trabecular Bone Strength and Microstructure in Inbred Strains of Mice , 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[4]  H. Nakajima,et al.  In Vivo Osteogenic Capability of Cultured Allogeneic Bone in Porous Hydroxyapatite: Immunosuppressive and Osteogenic Potential of FK506 In Vivo , 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[5]  L. Kennedy,et al.  Tacrolimus: An Alternative for Graft-Versus-Host Disease Prevention , 2000, The Annals of pharmacotherapy.

[6]  A Daluiski,et al.  The effect of regional gene therapy with bone morphogenetic protein-2-producing bone-marrow cells on the repair of segmental femoral defects in rats. , 1999, The Journal of bone and joint surgery. American volume.

[7]  T. Ruzicka,et al.  Tacrolimus: the drug for the turn of the millennium? , 1999, Archives of dermatology.

[8]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[9]  H. Ohgushi,et al.  Osteogenic Phenotype Expression of Allogeneic Rat Marrow Cells in Porous Hydroxyapatite Ceramics , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[10]  B. Cole,et al.  Bone marrow and recombinant human bone morphogenetic protein-2 in osseous repair. , 1999, Clinical orthopaedics and related research.

[11]  Darwin J. Prockop,et al.  Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta , 1999, Nature Medicine.

[12]  J. Lou,et al.  Gene therapy: Adenovirus‐mediated human bone morphogenetic protein‐2 gene transfer induces mesenchymal progenitor cell proliferation and differentiation in vitro and bone formation in vivo , 1999, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[13]  K. Kraus,et al.  Mesenchymal stem cells in osteobiology and applied bone regeneration. , 1998, Clinical orthopaedics and related research.

[14]  N. Wright,et al.  Induction of Bone Formation Using a Recombinant Adenoviral Vector Carrying the Human BMP-2 Gene in a Rabbit Spinal Fusion Model , 1998, Calcified Tissue International.

[15]  W. Hayes,et al.  Bone regeneration by implantation of purified, culture‐expanded human mesenchymal stem cells , 1998, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[16]  W. Blakemore,et al.  Use of a rat Y chromosome probe to determine the long-term survival of glial cells transplanted into areas of CNS demyelination , 1997, Journal of neurocytology.

[17]  S. Bruder,et al.  Osteogenic differentiation of purified, culture‐expanded human mesenchymal stem cells in vitro , 1997, Journal of cellular biochemistry.

[18]  S. Bruder,et al.  Growth kinetics, self‐renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation , 1997, Journal of cellular biochemistry.

[19]  C. Rivard,et al.  Artificial scaffolding materials for tissue extracellular matrix repair , 1996 .

[20]  S. Tamai,et al.  Osteogenic potential of allogeneic rat marrow cells in porous hydroxyapatite ceramics: A histological study , 1996, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[21]  S. Nilsson,et al.  In situ detection of individual transplanted bone marrow cells using FISH on sections of paraffin-embedded whole murine femurs. , 1996, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[22]  M. Aoki,et al.  Adenovirus‐mediated gene transfer into tendon and tendon sheath , 1996, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[23]  J. Zanchetta,et al.  Mechanical validation of a tomographic (pQCT) index for noninvasive estimation of rat femur bending strength. , 1996, Bone.

[24]  J. Werntz,et al.  Qualitative and quantitative analysis of orthotopic bone regeneration by marrow , 1996, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[25]  A I Caplan,et al.  Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use. , 1995, Bone marrow transplantation.

[26]  J. Sprent,et al.  Lymphocyte activation , 1994, Journal of cellular biochemistry.

[27]  A I Caplan,et al.  The mesengenic process. , 1994, Clinics in plastic surgery.

[28]  B. Thomson,et al.  Preliminary characterization of porcine bone marrow stromal cells: Skeletogenic potential, colony‐forming activity, and response to dexamethasone, transforming growth factor β, and basic fibroblast growth factor , 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[29]  V. Rosen,et al.  The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2). A radiographic, histological, and biomechanical study in rats. , 1992, The Journal of bone and joint surgery. American volume.

[30]  Arnold I. Caplan,et al.  Mesenchymal Stem Cells , 1991, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[31]  K. Satomura,et al.  Ultrastructure of mineralized nodules formed in rat bone marrow stromal cell culture in vitro. , 1991, Acta anatomica.

[32]  D. Gazit,et al.  Osteochondral differentiation and the emergence of stage-specific osteogenic cell-surface molecules by bone marrow cells in diffusion chambers. , 1990, Bone and mineral.

[33]  V. Rosen,et al.  The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2. , 1990, Biochemical and biophysical research communications.

[34]  F. Grinnell,et al.  Long-term culture of fibroblasts in contracted collagen gels: effects on cell growth and biosynthetic activity. , 1989, The Journal of investigative dermatology.

[35]  V. Goldberg,et al.  Heterotopic osteogenesis in porous ceramics induced by marrow cells , 1989, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[36]  M. Nogués,et al.  Epidural lipomatosis after renal transplantation--complete recovery without surgery. , 1988, Transplantation.

[37]  D. Gazit,et al.  Osteogenesis in in vivo diffusion chamber cultures of human marrow cells. , 1988, Bone and mineral.

[38]  K. Mark,et al.  Development of osteogenic tissue in diffusion chambers from early precursor cells in bone marrow of adult rats , 1987, Cell and Tissue Research.

[39]  D. N. Misra,et al.  The major histocompatibility complex of the rat. , 1987 .

[40]  D. N. Misra,et al.  THE MAJOR HISTOCOMPATIBILITY COMPLEX OF THE RAT1 , 1987 .

[41]  K. Lyons,et al.  Transient production of bone morphogenetic protein 2 by allogeneic transplanted transduced cells induces bone formation. , 2000, Human gene therapy.

[42]  J. Zanchetta,et al.  Dexamethasone effects on mechanical, geometric and densitometric properties of rat femur diaphyses as described by peripheral quantitative computerized tomography and bending tests. , 1995, Bone.

[43]  K. Doi,et al.  Results of vascularized joint allograft under immunosuppression with cyclosporine , 1993, Microsurgery.

[44]  A I Caplan,et al.  Characterization of cells with osteogenic potential from human marrow. , 1992, Bone.

[45]  A I Caplan,et al.  The osteogenic potential of culture-expanded rat marrow mesenchymal cells assayed in vivo in calcium phosphate ceramic blocks. , 1991, Clinical orthopaedics and related research.

[46]  S. Bruder,et al.  Terminal differentiation of osteogenic cells in the embryonic chick tibia is revealed by a monoclonal antibody against osteocytes. , 1990, Bone.

[47]  D. Evered,et al.  Cell and molecular biology of vertebrate hard tissues. , 1988, Ciba Foundation symposium.

[48]  K. Nakajima,et al.  Quantitative evaluation of the factors affecting the process of fibroblast-mediated collagen gel contraction by separating the process into three phases. , 1988, Collagen and related research.

[49]  A. Friedenstein,et al.  Stromal stem cells: marrow-derived osteogenic precursors. , 1988, Ciba Foundation symposium.

[50]  A. Weiland,et al.  Experimental vascularized bone allografting , 1987, Microsurgery.