Structural genomics of GPCRs.

[1]  H. Michel.  Three-dimensional crystals of a membrane protein complex. The photosynthetic reaction centre from Rhodopseudomonas viridis. , 1982, Journal of molecular biology.

[2]  A. Spirin,et al.  A continuous cell-free translation system capable of producing polypeptides in high yield. , 1988, Science.

[3]  J. Venter,et al.  Cloning, sequence analysis, and permanent expression of a human alpha 2-adrenergic receptor in Chinese hamster ovary cells. Evidence for independent pathways of receptor coupling to adenylate cyclase attenuation and activation. , 1989, The Journal of biological chemistry.

[4]  T. S. Kobilka,et al.  Enhancement of membrane insertion and function in a type IIIb membrane protein following introduction of a cleavable signal peptide. , 1992, The Journal of biological chemistry.

[5]  L L Iversen,et al.  Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[6]  C. Strader,et al.  Expression and solubilization of a recombinant human neurokinin-1 receptor in insect cells. , 1994, Journal of receptor research.

[7]  H. Michel,et al.  Expression of the human D2S dopamine receptor in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe: A comparative study , 1994, FEBS letters.

[8]  N. Adami,et al.  High-level expression of the human neurokinin-1 receptor in mammalian cell lines using the Semliki Forest virus expression system. , 1994, European journal of biochemistry.

[9]  B. Moss,et al.  Stringent chemical and thermal regulation of recombinant gene expression by vaccinia virus vectors in mammalian cells. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[10]  H. Michel,et al.  Fv fragment-mediated crystallization of the membrane protein bacterial cytochrome c oxidase , 1995, Nature Structural Biology.

[11]  C. Strader,et al.  Purification and reconstitution of a recombinant human neurokinin-1 receptor. , 1996, Journal of receptor and signal transduction research.

[12]  Paul E. Kennedy,et al.  HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor , 1996, Science.

[13]  J. Rosenbusch,et al.  Lipidic cubic phases: a novel concept for the crystallization of membrane proteins. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[14]  R. Stevens,et al.  Expression and Purification of the Saccharomyces cerevisiae α-Factor Receptor (Ste2p), a 7-Transmembrane-segment G Protein-coupled Receptor* , 1997, The Journal of Biological Chemistry.

[15]  R. Stevens,et al.  The human D1A dopamine receptor: heterologous expression in Saccharomyces cerevisiae and purification of the functional receptor. , 1998, Protein expression and purification.

[16]  J. Massagué.  TGF-beta signal transduction. , 1998, Annual review of biochemistry.

[17]  Heidi E. Hamm,et al.  The Many Faces of G Protein Signaling* , 1998, The Journal of Biological Chemistry.

[18]  R. Lefkowitz,et al.  G protein-coupled receptor kinases. , 1998, Annual review of biochemistry.

[19]  H. Michel,et al.  Comparative biochemical and pharmacological characterization of the mouse 5HT5A 5-hydroxytryptamine receptor and the human beta2-adrenergic receptor produced in the methylotrophic yeast Pichia pastoris. , 1998, The Biochemical journal.

[20]  A. Winter-Vann,et al.  Heterologous gene expression in a membrane-protein-specific system. , 1999, Protein expression and purification.

[21]  J. Bockaert,et al.  Molecular tinkering of G protein‐coupled receptors: an evolutionary success , 1999, The EMBO journal.

[22]  F. Graham.  Adenovirus vectors for high-efficiency gene transfer into mammalian cells , 2000, Immunology Today.

[23]  U. Gether.  Uncovering molecular mechanisms involved in activation of G protein-coupled receptors. , 2000, Endocrine reviews.

[24]  Solubilization and purification of the human ETB endothelin receptor produced by high-level fermentation in Pichia pastoris. , 2001, Receptors & channels.

[25]  Lukas K. Tamm,et al.  Structure of outer membrane protein A transmembrane domain by NMR spectroscopy , 2001, Nature Structural Biology.

[26]  Patent status of the therapeutically important G-protein-coupled receptors , 2001 .

[27]  R. Leurs,et al.  Recombinant Semliki Forest virus for over-expression and pharmacological characterisation of the histamine H(2) receptor in mammalian cells. , 2001, European journal of pharmacology.

[28]  K. Palczewski,et al.  Crystal Structure of Rhodopsin: A G‐Protein‐Coupled Receptor , 2002, Chembiochem : a European journal of chemical biology.

[29]  Philip J. Reeves,et al.  Structure and function in rhodopsin: A tetracycline-inducible system in stable mammalian cell lines for high-level expression of opsin mutants , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[30]  Roland Contreras,et al.  Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[31]  R. Grisshammer,et al.  Purification and characterization of the human adenosine A2a receptor functionally expressed in Escherichia coli , 2002 .

[32]  Dirk-Jan Slotboom,et al.  Lactococcus lactis as host for overproduction of functional membrane proteins. , 2003, Biochimica et biophysica acta.

[33]  D. Filippov,et al.  The conformation of neurotensin bound to its G protein-coupled receptor , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[34]  Haruki Nakamura,et al.  Structural genomics of membrane proteins. , 2003, Accounts of chemical research.

[35]  K. Lundström.  Semliki Forest virus vectors for rapid and high-level expression of integral membrane proteins , 2003 .

[36]  Krzysztof Palczewski,et al.  Organization of the G Protein-coupled Receptors Rhodopsin and Opsin in Native Membranes* , 2003, Journal of Biological Chemistry.

[37]  J. Banères,et al.  Structure-based analysis of GPCR function: conformational adaptation of both agonist and receptor upon leukotriene B4 binding to recombinant BLT1. , 2003, Journal of molecular biology.

[38]  E. Hermans.  Generation of model cell lines expressing recombinant G-protein-coupled receptors. , 2004, Methods in molecular biology.