Short-term tamoxifen administration improves hepatic steatosis and glucose intolerance through JNK/MAPK in mice
暂无分享,去创建一个
K. Dou | P. Song | Juanli Duan | Jingjing Liu | Chen Xu | Hao Xu | B. Ruan | Zhiqiang Fang | Jian-ping Ding | Lin Wang | Zhiwen Li
[1] N. P. H. Lan,et al. An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis , 2021, eLife.
[2] G. Ioannou. Epidemiology and risk-stratification of NAFLD-associated HCC. , 2021, Journal of hepatology.
[3] G. Sulaiman,et al. Layer-by-Layer Nanoparticles of Tamoxifen and Resveratrol for Dual Drug Delivery System and Potential Triple-Negative Breast Cancer Treatment , 2021, Pharmaceutics.
[4] B. Finck,et al. Emerging therapeutic approaches for the treatment of NAFLD and type 2 diabetes mellitus , 2021, Nature Reviews Endocrinology.
[5] K. Dou,et al. Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1. , 2021, Cell metabolism.
[6] Z. Younossi,et al. AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achieve Weight Loss in the Management of Nonalcoholic Fatty Liver Disease (NAFLD): Expert Review. , 2020, Gastroenterology.
[7] Y. Kubota,et al. Tamoxifen-Activated CreERT Impairs Retinal Angiogenesis Independently of Gene Deletion , 2020, Circulation research.
[8] S. Ikramuddin,et al. Nonalcoholic Steatohepatitis: A Review. , 2020, JAMA.
[9] Lan Xiao,et al. Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory , 2020, Nature Neuroscience.
[10] J. Chan,et al. Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory , 2020, Nature Neuroscience.
[11] Y. Ao,et al. Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions , 2019, Nature Communications.
[12] Li Lv,et al. Interplay between α2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory , 2019, Nature Communications.
[13] Alexander P. Yllanes,et al. Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumor efficacy , 2019, Breast Cancer Research and Treatment.
[14] Mamie Yu,et al. Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility , 2019, Cell.
[15] A. Omar,et al. Enhanced anti-mammary gland cancer activities of tamoxifen-loaded erythropoietin-coated drug delivery system , 2019, PloS one.
[16] K. Unsicker,et al. Selective Liver Estrogen Receptor α Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice , 2019, Hepatology communications.
[17] David Lumelsky,et al. Tamoxifen improves glucose tolerance in a delivery, sex, and strain-dependent manner in mice , 2018, bioRxiv.
[18] Z. Younossi. Non-alcoholic fatty liver disease - A global public health perspective. , 2019, Journal of hepatology.
[19] M. Dallak. Acylated ghrelin induces but deacylated ghrelin prevents hepatic steatosis and insulin resistance in lean rats: Effects on DAG/ PKC/JNK pathway. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[20] K. Dou,et al. Endothelial Notch activation reshapes the angiocrine of sinusoidal endothelia to aggravate liver fibrosis and blunt regeneration in mice , 2018, Hepatology.
[21] Michael Charlton,et al. The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases , 2018, Hepatology.
[22] T. Bihani,et al. Selective estrogen receptor modulators (SERMs) and selective estrogen receptor degraders (SERDs) in cancer treatment. , 2017, Pharmacology & therapeutics.
[23] L. Henry,et al. NAFLD AND NASH: Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention , 2018 .
[24] Hervé Guillou,et al. Selective Activation of Estrogen Receptor α Activation Function-1 Is Sufficient to Prevent Obesity, Steatosis, and Insulin Resistance in Mouse. , 2017, The American journal of pathology.
[25] Parth Patel,et al. Delineating the molecular mechanisms of tamoxifen's oncolytic actions in estrogen receptor-negative cancers. , 2016, European journal of pharmacology.
[26] F. Mauvais-Jarvis,et al. Effect of selective estrogen receptor modulators on metabolic homeostasis. , 2016, Biochimie.
[27] N. Lane,et al. Optimizing tamoxifen-inducible Cre/loxp system to reduce tamoxifen effect on bone turnover in long bones of young mice. , 2015, Bone.
[28] H. Fine,et al. A phase II trial of tamoxifen and bortezomib in patients with recurrent malignant gliomas , 2015, Journal of Neuro-Oncology.
[29] Jieli Lu,et al. Hepatic estrogen receptor α improves hepatosteatosis through upregulation of small heterodimer partner. , 2015, Journal of hepatology.
[30] Lingqiang Zhang,et al. The Effect and Mechanism of Tamoxifen-Induced Hepatocyte Steatosis in Vitro , 2014, International journal of molecular sciences.
[31] David W. Henry,et al. Safety and efficacy of high‐dose tamoxifen and sulindac for desmoid tumor in children: Results of a Children's Oncology Group (COG) Phase II Study , 2013, Pediatric blood & cancer.
[32] K. Tsuneyama,et al. Mechanisms of the hepatoprotective effects of tamoxifen against drug-induced and chemical-induced acute liver injuries. , 2012, Toxicology and applied pharmacology.
[33] K. Tsuneyama,et al. Hepatoprotective effect of tamoxifen on steatosis and non-alcoholic steatohepatitis in mouse models. , 2012, The Journal of toxicological sciences.
[34] G. Kong,et al. Gene expression profiling of murine hepatic steatosis induced by tamoxifen. , 2010, Toxicology letters.
[35] D. Vance,et al. Tamoxifen induces triacylglycerol accumulation in the mouse liver by activation of fatty acid synthesis , 2010, Hepatology.
[36] Nihal Ahmad,et al. Dose translation from animal to human studies revisited , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[37] M. S. Ozers,et al. Development of a coactivator displacement assay for the orphan receptor estrogen-related receptor-gamma using time-resolved fluorescence resonance energy transfer. , 2006, Analytical biochemistry.
[38] C. Lelliott,et al. Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[39] Karen M. Speirs,et al. Expert Review テリスロマイシン , 2005 .
[40] U. Veronesi,et al. Incidence and risk factors for non-alcoholic steatohepatitis: prospective study of 5408 women enrolled in Italian tamoxifen chemoprevention trial , 2005, BMJ : British Medical Journal.
[41] Yoshikuni Yakabe,et al. Comparison of the Hershberger assay and androgen receptor binding assay of twelve chemicals. , 2004, Toxicology.
[42] G. Jacquemin. [Nonalcoholic steatohepatitis: a review]. , 2003, Revue medicale de Liege.
[43] T. Clarkson,et al. Estrogen replacement therapy, atherosclerosis, and vascular function. , 2002, Cardiovascular research.
[44] A. Franchitto,et al. Estrogens stimulate proliferation of intrahepatic biliary epithelium in rats. , 2000, Gastroenterology.
[45] A. Howell. Tamoxifen versus the newer SERMs: what is the evidence? , 2000, Annals of Oncology.
[46] Q. Cai,et al. Tamoxifen-induced transient multifocal hepatic fatty infiltration , 2000, American Journal of Gastroenterology.
[47] Y. Ogawa,et al. Tamoxifen-induced fatty liver in patients with breast cancer , 1998, The Lancet.
[48] J. Vonesch,et al. Spatio-temporally controlled site-specific somatic mutagenesis in the mouse. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[49] P Chambon,et al. Ligand-activated site-specific recombination in mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[50] Y. Horsmans,et al. Tamoxifen-Induced Steatohepatitis , 1996, Annals of Internal Medicine.
[51] J. Erban,et al. Tamoxifen-Induced Steatohepatitis , 1995, Annals of Internal Medicine.
[52] G. Hortobagyi,et al. Use of tamoxifen for breast cancer: twenty-eight years later. , 1995, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[53] R. Papac,et al. Hormonal therapy for metastatic renal cell carcinoma combined androgen and provera followed by high dose tamoxifen. , 1993, European journal of cancer.
[54] E. Winer,et al. High-dose oral tamoxifen, a potential multidrug-resistance-reversal agent: phase I trial in combination with vinblastine. , 1992, Journal of the National Cancer Institute.
[55] S. Legha,et al. Tamoxifen in the treatment of breast cancer. , 1988, Annals of internal medicine.
[56] Robert C. Wolpert,et al. A Review of the , 1985 .
[57] B. Edwards,et al. Evaluation of tamoxifen doses with and without fluoxymesterone in advanced breast cancer. , 1983, Annals of internal medicine.