Hepatocellular carcinoma-targeting oncolytic adenovirus overcomes hypoxic tumor microenvironment and effectively disperses through both central and peripheral tumor regions
暂无分享,去创建一个
A. Yoon | Jinwoo Hong | C. Yun | Minjung Kim
[1] B. Chauffert,et al. Alpha-foetoprotein (AFP): A multi-purpose marker in hepatocellular carcinoma. , 2016, Clinica chimica acta; international journal of clinical chemistry.
[2] A. Yoon,et al. Antitumor effect and safety profile of systemically delivered oncolytic adenovirus complexed with EGFR-targeted PAMAM-based dendrimer in orthotopic lung tumor model. , 2016, Journal of controlled release : official journal of the Controlled Release Society.
[3] A. Yoon,et al. A vesicular stomatitis virus glycoprotein epitope-incorporated oncolytic adenovirus overcomes CAR-dependency and shows markedly enhanced cancer cell killing and suppression of tumor growth , 2015, Oncotarget.
[4] Peter R. Cook,et al. Why the activity of a gene depends on its neighbors. , 2015, Trends in genetics : TIG.
[5] J. Trojan,et al. Novel drugs in clinical development for hepatocellular carcinoma , 2015, Expert opinion on investigational drugs.
[6] Zhaohui Tang,et al. Peritumoral Neuropilin-1 and VEGF receptor-2 expression increases time to recurrence in hepatocellular carcinoma patients undergoing curative hepatectomy , 2014, Oncotarget.
[7] Molin Wang,et al. Prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers from two phase III randomized adjuvant breast cancer trials: ECOG 2197 and ECOG 1199. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[8] E. Rofstad,et al. Tumor Interstitial Fluid Pressure—A Link between Tumor Hypoxia, Microvascular Density, and Lymph Node Metastasis , 2014, Neoplasia.
[9] O. Podhajcer,et al. Enhanced CRAd activity using enhancer motifs driven by a nucleosome positioning sequence. , 2013, Molecular therapy : the journal of the American Society of Gene Therapy.
[10] Guan-Cheng Li,et al. Tumor markers for hepatocellular carcinoma , 2013, Molecular and clinical oncology.
[11] G. Semenza. Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. , 2012, Trends in pharmacological sciences.
[12] C. Yun,et al. A Hypoxia- and α-Fetoprotein–Dependent Oncolytic Adenovirus Exhibits Specific Killing of Hepatocellular Carcinomas , 2010, Clinical Cancer Research.
[13] Hui Zhou,et al. Liver‐enriched transcription factors regulate MicroRNA‐122 that targets CUTL1 during liver development , 2010, Hepatology.
[14] Q. Lan,et al. Development of clinically relevant orthotopic xenograft mouse model of metastatic lung cancer and glioblastoma through surgical tumor tissues injection with trocar , 2010, Journal of experimental & clinical cancer research : CR.
[15] F. Lang,et al. Oncolytic adenovirus: preclinical and clinical studies in patients with human malignant gliomas. , 2009, Current gene therapy.
[16] O. Podhajcer,et al. Suppression of cancer growth by nonviral gene therapy based on a novel reactive oxygen species-responsive promoter. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.
[17] W. De,et al. Adenovirus-mediated suicide gene therapy under the control of Cox-2 promoter for colorectal cancer , 2009, Cancer biology & therapy.
[18] E. Galanis,et al. Phase I clinical trial of locoregional administration of the oncolytic adenovirus ONYX-015 in combination with mitomycin-C, doxorubicin, and cisplatin chemotherapy in patients with advanced sarcomas. , 2009, Methods in molecular biology.
[19] M. Celeste Simon,et al. The impact of O2 availability on human cancer , 2008, Nature Reviews Cancer.
[20] H. Yasuda,et al. Solid tumor physiology and hypoxia-induced chemo/radio-resistance: novel strategy for cancer therapy: nitric oxide donor as a therapeutic enhancer. , 2008, Nitric oxide : biology and chemistry.
[21] M. Miyazaki,et al. Clinical significance of α‐fetoprotein: involvement in proliferation, angiogenesis, and apoptosis of hepatocellular carcinoma , 2008, Journal of gastroenterology and hepatology.
[22] P. Stewart,et al. Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo , 2008, Proceedings of the National Academy of Sciences.
[23] C. Napoli,et al. Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer , 2008, Cell.
[24] R. Johnson,et al. Hypoxia: A key regulator of angiogenesis in cancer , 2007, Cancer and Metastasis Reviews.
[25] R. Millikan,et al. CA IX is an Independent Prognostic Marker in Premenopausal Breast Cancer Patients with One to Three Positive Lymph Nodes and a Putative Marker of Radiation Resistance , 2006, Clinical Cancer Research.
[26] A. Parker,et al. Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes. , 2006, Blood.
[27] Byeong‐Woo Park,et al. Markedly enhanced cytolysis by E1B-19kD-deleted oncolytic adenovirus in combination with cisplatin. , 2006, Human gene therapy.
[28] D. Brizel,et al. Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study. , 2005, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
[29] B. Shen,et al. Effect of hypoxia on Ad5 infection, transgene expression and replication , 2005, Gene Therapy.
[30] Bart Everts,et al. Replication-selective oncolytic viruses in the treatment of cancer , 2005, Cancer Gene Therapy.
[31] Josepa Ribes,et al. Primary liver cancer: worldwide incidence and trends. , 2004, Gastroenterology.
[32] W. Rom,et al. 278. Hypoxia Reduces Adenoviral Replication in Cancer Cells by Down-Regulation of Viral Protein Expression , 2004 .
[33] G. Powis,et al. Hypoxia inducible factor-1alpha as a cancer drug target. , 2004, Molecular cancer therapeutics.
[34] G. Powis,et al. Hypoxia inducible factor as a cancer drug target. , 2003, Current cancer drug targets.
[35] Hoguen Kim,et al. Ad-mTERT-delta19, a conditional replication-competent adenovirus driven by the human telomerase promoter, selectively replicates in and elicits cytopathic effect in a cancer cell-specific manner. , 2003, Human gene therapy.
[36] Erwin G. Van Meir,et al. Replicative oncolytic adenoviruses in multimodal cancer regimens. , 2003, Human gene therapy.
[37] K. Jungermann,et al. Hypoxia-inducible factor-1 and hypoxia response elements mediate the induction of plasminogen activator inhibitor-1 gene expression by insulin in primary rat hepatocytes. , 2003, Blood.
[38] Joo‐Hang Kim,et al. Evaluation of E1B gene-attenuated replicating adenoviruses for cancer gene therapy , 2002, Cancer Gene Therapy.
[39] D. Nettelbeck,et al. Novel oncolytic adenoviruses targeted to melanoma: specific viral replication and cytolysis by expression of E1A mutants from the tyrosinase enhancer/promoter. , 2002, Cancer research.
[40] Joo‐Hang Kim,et al. Antitumoral effects of recombinant adenovirus YKL-1001, conditionally replicating in alpha-fetoprotein-producing human liver cancer cells. , 2002, Cancer letters.
[41] C. Gomer,et al. Enhanced photodynamic therapy efficacy with inducible suicide gene therapy controlled by the grp promoter. , 2002, Cancer research.
[42] D. Kirn. Oncolytic virotherapy for cancer with the adenovirus dl1520 (Onyx-015): results of Phase I and II trials , 2001, Expert opinion on biological therapy.
[43] M. Colombo. Screening for cancer in viral hepatitis. , 2001, Clinics in liver disease.
[44] M. Gulley,et al. A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[45] G. Semenza,et al. Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha. , 2000, Genes & development.
[46] M. Gulley,et al. Erratum: A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer (Clinical Cancer Research (2000) 6 (798-806)) , 2000 .
[47] M. Makuuchi,et al. Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide. , 2000, Blood.
[48] Xianglin Shi,et al. Regulation of a Cell Type-specific Silencer in the Human Interleukin-3 Gene Promoter by the Transcription Factor YY1 and an AP2 Sequence-recognizing Factor* , 1999, The Journal of Biological Chemistry.
[49] Y. Chiang,et al. A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma. , 1999, Human gene therapy.
[50] N. Koide,et al. α-Fetoprotein–producing gastric cancer: histochemical analysis of cell proliferation, apoptosis, and angiogenesis , 1999, American Journal of Gastroenterology.
[51] S. Kaneko,et al. Enhanced and specific gene expression via tissue-specific production of Cre recombinase using adenovirus vector. , 1998, Biochemical and biophysical research communications.
[52] J. Simons,et al. Prostate attenuated replication competent adenovirus (ARCA) CN706: a selective cytotoxic for prostate-specific antigen-positive prostate cancer cells. , 1997, Cancer research.
[53] R. Weinberg,et al. The retinoblastoma protein and cell cycle control , 1995, Cell.
[54] Yamamura Ken-ichi,et al. Efficient selection for high-expression transfectants with a novel eukaryotic vector , 1991 .
[55] H. Niwa,et al. Efficient selection for high-expression transfectants with a novel eukaryotic vector. , 1991, Gene.
[56] H. Nakabayashi,et al. A position-dependent silencer plays a major role in repressing alpha-fetoprotein expression in human hepatoma , 1991, Molecular and cellular biology.
[57] D. W. Kim,et al. Use of the human elongation factor 1α promoter as a versatile and efficient expression system , 1990 .
[58] S. Sugano,et al. Use of the human elongation factor 1 alpha promoter as a versatile and efficient expression system. , 1990, Gene.
[59] R. Cortese,et al. The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain , 1989, Cell.
[60] K. Watanabe,et al. Transcriptional regulation of alpha-fetoprotein expression by dexamethasone in human hepatoma cells. , 1989, The Journal of biological chemistry.
[61] T. Tamaoki,et al. Interaction of a hepatoma-specific nuclear factor with transcription-regulatory sequences of the human alpha-fetoprotein and albumin genes , 1988, Molecular and cellular biology.
[62] K. Watanabe,et al. Cell-specific enhancer activity in a far upstream region of the human alpha-fetoprotein gene. , 1987, The Journal of biological chemistry.
[63] D. Woodfield. Hepatocellular carcinoma. , 1986, The New Zealand medical journal.