Integrated physiological flow simulator and pulse sequence monitoring system for MRI

A compact flow simulator for generating accurate pulsatile flow in a clinical magnetic resonance imaging (MRI) environment has been developed and integrated with a data acquisition (DAQ) system for recording scanner system activity and physiological waveforms. The flow simulator is relatively inexpensive, easy to construct and is controlled from a standard PC. The flow simulator is robust to repeated disassembly and reassembly (normalised cross-correlation 0.97) and generates accurate pulsatile flow (normalised cross-correlation 0.94). The DAQ system was used to monitor a standard MRI pulse sequence used in MR angiography and latent delays in the scanner gating subsystem.

[1]  Maria Drangova,et al.  Multisite trial of MR flow measurement: Phantom and protocol design , 2005, Journal of magnetic resonance imaging : JMRI.

[2]  P R Hoskins,et al.  Quantitative analysis of PC MRI velocity maps: pulsatile flow in cylindrical vessels. , 2001, Magnetic resonance imaging.

[3]  D B Plewes,et al.  An MR compatible flow simulator for intravascular pressure simulation. , 1995, Medical physics.

[4]  R. Herfkens,et al.  Phase contrast cine magnetic resonance imaging. , 1991, Magnetic resonance quarterly.

[5]  R. F. Smith,et al.  Anthropomorphic carotid bifurcation phantom for MRI applications , 1999, Journal of magnetic resonance imaging : JMRI.

[6]  J Hennig,et al.  RARE imaging: A fast imaging method for clinical MR , 1986, Magnetic resonance in medicine.

[7]  T K Foo,et al.  Improved ejection fraction and flow velocity estimates with use of view sharing and uniform repetition time excitation with fast cardiac techniques. , 1995, Radiology.

[8]  J. N. Petersen Digitally controlled system for reproducing blood flow waveformsin vitro , 2006, Medical and Biological Engineering and Computing.

[9]  K. Roman,et al.  Real‐time Fourier velocity encoding: An in vivo evaluation , 2005, Journal of magnetic resonance imaging : JMRI.

[10]  P R Hoskins,et al.  A computer controlled flow phantom for generation of physiological Doppler waveforms , 1989, Physics in medicine and biology.

[11]  A. Fenster,et al.  Computer‐controlled flow simulator for MR flow studies , 1992, Journal of magnetic resonance imaging : JMRI.

[12]  Richard Frayne,et al.  Accuracy of MR phase contrast velocity measurements for unsteady flow , 1995, Journal of magnetic resonance imaging : JMRI.