Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia
暂无分享,去创建一个
[1] S. Pyne,et al. Role of sphingosine kinases and lipid phosphate phosphatases in regulating spatial sphingosine 1-phosphate signalling in health and disease. , 2009, Cellular signalling.
[2] T. Okada,et al. Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system. , 2009, Cellular signalling.
[3] T. Ohmori,et al. Antagonism of Sphingosine 1-Phosphate Receptor-2 Enhances Migration of Neural Progenitor Cells Toward an Area of Brain Infarction , 2008, Stroke.
[4] M. Tansey,et al. Journal of Neuroinflammation BioMed Central Review , 2008 .
[5] S. Milstien,et al. Regulation and functions of sphingosine kinases in the brain. , 2008, Biochimica et biophysica acta.
[6] S. Milstien,et al. Apoptosis induces expression of sphingosine kinase 1 to release sphingosine‐1‐phosphate as a “come‐and‐get‐me” signal , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[7] L. Obeid,et al. Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages. , 2008, Prostaglandins & other lipid mediators.
[8] A. Melendez. Sphingosine kinase signalling in immune cells: potential as novel therapeutic targets. , 2008, Biochimica et biophysica acta.
[9] Y. Zhuang,et al. Suppression of Ulcerative Colitis in Mice by Orally Available Inhibitors of Sphingosine Kinase , 2008, Digestive Diseases and Sciences.
[10] R. Woltjer,et al. Manipulation of microglial activation as a therapeutic strategy in Alzheimer's disease. , 2007, Current medicinal chemistry.
[11] S. Milstien,et al. Autocrine and paracrine roles of sphingosine-1-phosphate , 2007, Trends in Endocrinology & Metabolism.
[12] W. Robberecht,et al. Microglia in amyotrophic lateral sclerosis. , 2007, Acta neurologica Belgica.
[13] E. Ling,et al. Microglial activation and its implications in the brain diseases. , 2007, Current medicinal chemistry.
[14] M. ter Braak,et al. Regulation and functional roles of sphingosine kinases , 2007, Naunyn-Schmiedeberg's Archives of Pharmacology.
[15] B. Wattenberg,et al. The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function Published, JLR Papers in Press, March 6, 2006. , 2006, Journal of Lipid Research.
[16] P. Peterson,et al. Microglia as a Pharmacological Target in Infectious and Inflammatory Diseases of the Brain , 2006, Journal of Neuroimmune Pharmacology.
[17] R. Proia,et al. IgE-dependent Activation of Sphingosine Kinases 1 and 2 and Secretion of Sphingosine 1-Phosphate Requires Fyn Kinase and Contributes to Mast Cell Responses* , 2006, Journal of Biological Chemistry.
[18] E. Goetzl,et al. Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network , 2005, Nature Reviews Immunology.
[19] S. Payne,et al. Expression of SphK1 impairs degranulation and motility of RBL-2H3 mast cells by desensitizing S1P receptors. , 2005, Blood.
[20] M. Block,et al. Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism , 2005, Progress in Neurobiology.
[21] S. T. Dheen,et al. Retinoic acid inhibits expression of TNF‐α and iNOS in activated rat microglia , 2005 .
[22] A. Olivera,et al. Sphingolipids and the Balancing of Immune Cell Function: Lessons from the Mast Cell , 2005, The Journal of Immunology.
[23] F. Vilhardt. Microglia: phagocyte and glia cell. , 2005, The international journal of biochemistry & cell biology.
[24] A. Melendez,et al. Anaphylatoxin Signaling in Human Neutrophils , 2004, Journal of Biological Chemistry.
[25] J. Chun,et al. Lysophospholipid G Protein-coupled Receptors* , 2004, Journal of Biological Chemistry.
[26] T. Hla,et al. Point-Counterpoint of Sphingosine 1-Phosphate Metabolism , 2004, Circulation research.
[27] T. Rao,et al. Microglial activation state and lysophospholipid acid receptor expression , 2003, International Journal of Developmental Neuroscience.
[28] S. Rivest,et al. Glucocorticoids Play a Fundamental Role in Protecting the Brain during Innate Immune Response , 2003, The Journal of Neuroscience.
[29] T. Hla,et al. Sphingosine-1-phosphate signaling in endothelial activation. , 2003, Journal of atherosclerosis and thrombosis.
[30] Sarah Spiegel,et al. Sphingosine-1-phosphate: an enigmatic signalling lipid , 2003, Nature Reviews Molecular Cell Biology.
[31] S. Rivest,et al. Endotoxemia Prevents the Cerebral Inflammatory Wave Induced by Intraparenchymal Lipopolysaccharide Injection: Role of Glucocorticoids and CD141 , 2002, The Journal of Immunology.
[32] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[33] N. Rothwell,et al. Cytokines and acute neurodegeneration , 2001, Nature Reviews Neuroscience.
[34] A. Hao,et al. Origin of microglia , 2001, Microscopy research and technique.
[35] G. Landreth,et al. β-Amyloid Stimulation of Microglia and Monocytes Results in TNFα-Dependent Expression of Inducible Nitric Oxide Synthase and Neuronal Apoptosis , 2001, The Journal of Neuroscience.
[36] A. Hara,et al. Tumor necrosis factor-α-mediated signal transduction in human neutrophils: Involvement of sphingomyelin metabolites in the priming effect of tnf-α on the fMLP-stimulated superoxide production , 1999 .
[37] W. Streit,et al. Reactive microgliosis , 1999, Progress in Neurobiology.
[38] H. Kettenmann,et al. An immortalized cell line expresses properties of activated microglial cells , 1992, Journal of neuroscience research.