Group II metabotropic glutamate receptor activation on peripheral nociceptors modulates TRPV1 function

[1]  J. Du,et al.  Group II metabotropic glutamate receptor activation attenuates peripheral sensitization in inflammatory states , 2008, Neuroscience.

[2]  S. Carlton,et al.  Colocalization of metabotropic glutamate receptors in rat dorsal root ganglion cells , 2007, The Journal of comparative neurology.

[3]  W. Willis,et al.  Activation of protein kinase B/Akt in the periphery contributes to pain behavior induced by capsaicin in rats , 2007, Neuroscience.

[4]  J. Du,et al.  Kainate-induced excitation and sensitization of nociceptors in normal and inflamed rat glabrous skin , 2006, Neuroscience.

[5]  K. Bölcskei,et al.  Investigation of the role of TRPV1 receptors in acute and chronic nociceptive processes using gene-deficient mice , 2005, Pain.

[6]  S. Ohtori,et al.  Expression and Co-Expression of VR1, CGRP, and IB4-Binding Glycoprotein in Dorsal Root Ganglion Neurons in Rats: Differences Between the Disc Afferents and the Cutaneous Afferents , 2005, Spine.

[7]  C. Stucky,et al.  Peripheral inflammation selectively increases TRPV1 function in IB4-positive sensory neurons from adult mouse , 2005, Pain.

[8]  D. Mohapatra,et al.  Regulation of Ca2+-dependent Desensitization in the Vanilloid Receptor TRPV1 by Calcineurin and cAMP-dependent Protein Kinase* , 2005, Journal of Biological Chemistry.

[9]  R. Coggeshall,et al.  Somatostatin modulates the transient receptor potential vanilloid 1 (TRPV1) ion channel , 2004, Pain.

[10]  Z. Bashir,et al.  Metabotropic glutamate receptor signalling in perirhinal cortical neurons , 2004, Molecular and Cellular Neuroscience.

[11]  D. Mohapatra,et al.  Desensitization of Capsaicin-activated Currents in the Vanilloid Receptor TRPV1 Is Decreased by the Cyclic AMP-dependent Protein Kinase Pathway* , 2003, Journal of Biological Chemistry.

[12]  Dongni Yang,et al.  Peripheral group II metabotropic glutamate receptors mediate endogenous anti-allodynia in inflammation , 2003, Pain.

[13]  R. Coggeshall,et al.  N-methyl-d-aspartate-induced excitation and sensitization of normal and inflamed nociceptors , 2003, Neuroscience.

[14]  M. Iadarola,et al.  Protein Kinase Cα Is Required for Vanilloid Receptor 1 Activation , 2002, The Journal of Biological Chemistry.

[15]  S. Iyengar,et al.  Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats , 2002, Pharmacology Biochemistry and Behavior.

[16]  D. J. Brasier,et al.  cAMP-Dependent Protein Kinase Regulates Desensitization of the Capsaicin Receptor (VR1) by Direct Phosphorylation , 2002, Neuron.

[17]  Dongni Yang,et al.  Peripheral Group II Metabotropic Glutamate Receptors (mGluR2/3) Regulate Prostaglandin E2-Mediated Sensitization of Capsaicin Responses and Thermal Nociception , 2002, The Journal of Neuroscience.

[18]  A. Caricasole,et al.  L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors. , 2002, Molecular pharmacology.

[19]  M. Tominaga,et al.  Direct Phosphorylation of Capsaicin Receptor VR1 by Protein Kinase Cε and Identification of Two Target Serine Residues* , 2002, The Journal of Biological Chemistry.

[20]  P. Headley,et al.  Systemic pre‐treatment with a group II mGlu agonist, LY379268, reduces hyperalgesia in vivo , 2002, British journal of pharmacology.

[21]  C. Hulsebosch,et al.  Role of Group II and Group III Metabotropic Glutamate Receptors in Spinal Cord Injury , 2002, Experimental Neurology.

[22]  S. Carlton,et al.  Metabotropic glutamate 1α receptors on peripheral primary afferent fibers: their role in nociception , 2001, Brain Research.

[23]  R. Coggeshall,et al.  Localization of metabotropic glutamate receptors 2/3 on primary afferent axons in the rat , 2001, Neuroscience.

[24]  A. Moriondo,et al.  Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide , 2001, The Journal of physiology.

[25]  R. Coggeshall,et al.  Tonic Control of Peripheral Cutaneous Nociceptors by Somatostatin Receptors , 2001, The Journal of Neuroscience.

[26]  T. Bisogno,et al.  The vanilloid receptor (VR1)‐mediated effects of anandamide are potently enhanced by the cAMP‐dependent protein kinase , 2001, Journal of neurochemistry.

[27]  J. Mateos,et al.  Immunoreactivity for the group III metabotropic glutamate receptor subtype mGluR4a in the superficial laminae of the rat spinal dorsal horn , 2001, The Journal of comparative neurology.

[28]  L. Premkumar,et al.  Induction of vanilloid receptor channel activity by protein kinase C , 2000, Nature.

[29]  W. Willis,et al.  Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells. , 2000, Journal of neurophysiology.

[30]  S. Bingham,et al.  Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia , 2000, Nature.

[31]  A I Basbaum,et al.  Impaired nociception and pain sensation in mice lacking the capsaicin receptor. , 2000, Science.

[32]  J. Harris,et al.  Neuroprotective Actions of Novel and Potent Ligands of Group I and Group II Metabotropic Glutamate Receptors , 1999, Annals of the New York Academy of Sciences.

[33]  D. Jane,et al.  Pharmacological agents acting at subtypes of metabotropic glutamate receptors , 1999, Neuropharmacology.

[34]  J. Levine,et al.  Role of Protein Kinase A in the Maintenance of Inflammatory Pain , 1999, The Journal of Neuroscience.

[35]  R. Elde,et al.  Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites , 1999, The European journal of neuroscience.

[36]  G. Michael,et al.  Differential Expression of the mRNA for the Vanilloid Receptor Subtype 1 in Cells of the Adult Rat Dorsal Root and Nodose Ganglia and Its Downregulation by Axotomy , 1999, The Journal of Neuroscience.

[37]  A. Basbaum,et al.  The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli , 1998, Neuron.

[38]  J. Lopshire,et al.  The cAMP Transduction Cascade Mediates the Prostaglandin E2 Enhancement of the Capsaicin-Elicited Current in Rat Sensory Neurons: Whole-Cell and Single-Channel Studies , 1998, The Journal of Neuroscience.

[39]  D. Julius,et al.  The capsaicin receptor: a heat-activated ion channel in the pain pathway , 1997, Nature.

[40]  H. Tse,et al.  α-methyl derivatives of serine-O-phosphate as novel, selective competitive metabotropic glutamate receptor antagonists , 1996, Neuropharmacology.

[41]  S. Nakanishi,et al.  Presynaptic localization of a metabotropic glutamate receptor, mGluR7, in the primary afferent neurons: an immunohistochemical study in the rat , 1995, Neuroscience Letters.

[42]  D. Schoepp,et al.  Selective inhibition of forskolin-stimulated cyclic AMP formation in rat hippocampus by a novel mGluR agonist, 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate , 1995, Neuropharmacology.

[43]  D. Schoepp.  Novel functions for subtypes of metabotropic glutamate receptors , 1994, Neurochemistry International.

[44]  M. Masu,et al.  Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4 , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[45]  H O Handwerker,et al.  Responsiveness and functional attributes of electrically localized terminals of cutaneous C-fibers in vivo and in vitro. , 1992, Journal of neurophysiology.

[46]  M. Koltzenburg,et al.  The nociceptor sensitization by bradykinin does not depend on sympathetic neurons , 1992, Neuroscience.

[47]  J. Levine,et al.  Prostaglandins sensitize nociceptors in cell culture , 1991, Neuroscience Letters.

[48]  R. Dubner,et al.  A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia , 1987, Pain.

[49]  P. Reeh,et al.  Sensory receptors in mammalian skin in an in vitro preparation , 1986, Neuroscience Letters.

[50]  M. Zimmermann,et al.  Ethical guidelines for investigations of experimental pain in conscious animals , 1983, Pain.

[51]  M. Iadarola,et al.  Protein kinase C(alpha) is required for vanilloid receptor 1 activation. Evidence for multiple signaling pathways. , 2002, The Journal of biological chemistry.

[52]  D. Julius,et al.  The vanilloid receptor: a molecular gateway to the pain pathway. , 2001, Annual review of neuroscience.

[53]  P. Conn,et al.  Metabotropic glutamate receptors in brain function and pathology. , 1993, Trends in pharmacological sciences.