Proposed Multi-linear Regression Model to Identify Cyclooxygenase-2 Selective Active Pharmaceutical Ingredients

[1]  Zahra Payandeh,et al.  Immunoinformatics: In Silico Approaches and Computational Design of a Multi-epitope, Immunogenic Protein , 2019, International reviews of immunology.

[2]  M. Rasaee,et al.  Structure Based Screening for Inhibitory Therapeutics of CTLA-4 Unveiled New Insights About Biology of ACTH , 2019, International Journal of Peptide Research and Therapeutics.

[3]  Y. Ghasemi,et al.  Trimeric autotransporter adhesins in Acinetobacter baumannii, coincidental evolution at work. , 2019, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

[4]  T. Usha,et al.  Potential Cyclooxygenase (COX-2) enzyme inhibitors from Myrica nagi-from in-silico to in-vitro investigation , 2019, Pharmacognosy Magazine.

[5]  Shakiba Darvish Alipour Astaneh,et al.  Antigenic Properties of Iron Regulated Proteins in Acinetobacter baumannii: An In Silico Approach , 2019, International Journal of Peptide Research and Therapeutics.

[6]  I. Rasooli,et al.  In Silico Engineering Towards Enhancement of Bap–VHH Monoclonal Antibody Binding Affinity , 2019, International Journal of Peptide Research and Therapeutics.

[7]  A. Dhir.  An update of cyclooxygenase (COX)-inhibitors in epilepsy disorders , 2018, Expert opinion on investigational drugs.

[8]  M. Rajabibazl,et al.  Affinity maturation and characterization of the ofatumumab monoclonal antibody , 2018, Journal of cellular biochemistry.

[9]  Zahra Payandeh,et al.  Ofatumumab Monoclonal Antibody Affinity Maturation Through in silico Modeling , 2018, Iranian biomedical journal.

[10]  M. Hedayati,et al.  The Effect of Differentially Designed Fusion Proteins to Elicit Efficient Anti-human Thyroid Stimulating Hormone Immune Responses. , 2018, Iranian Journal of Allergy, Asthma and Immunology.

[11]  R. Halabian,et al.  In Silico Analyses of Staphylococcal Enterotoxin B as a DNA Vaccine for Cancer Therapy , 2018, International Journal of Peptide Research and Therapeutics.

[12]  M. Rasaee,et al.  In silico Prediction and in vitro Verification of a Novel Multi-Epitope Antigen for HBV Detection , 2017, Molecular Genetics, Microbiology and Virology.

[13]  S. Khalili,et al.  Structural analyses of the interactions between the thyme active ingredients and human serum albumin , 2017 .

[14]  Jahan B Ghasemi,et al.  A quantitative structure- property relationship of gas chromatographic/mass spectrometric retention data of 85 volatile organic compounds as air pollutant materials by multivariate methods , 2012, Chemistry Central Journal.

[15]  N. Shimizu,et al.  High levels of human recombinant cyclooxygenase-1 expression in mammalian cells using a novel gene amplification method. , 2011, Protein expression and purification.

[16]  Y. S. Prabhakar,et al.  A QSAR study on 2-(4-methylpiperazin-1-yl)quinoxalines as human histamine H4 receptor ligands , 2011, Journal of enzyme inhibition and medicinal chemistry.

[17]  D. Latha,et al.  QSAR study for the prediction of IC50 and Log P for 5-N-Acetyl-Beta-D- Neuraminic Acid structurally similar compounds using stepwise (multivariate) linear regression , 2010 .

[18]  R. Harris,et al.  Renal localization and regulation of 15-hydroxyprostaglandin dehydrogenase. , 2008, American journal of physiology. Renal physiology.

[19]  Toshiaki Shimizu,et al.  Expression of COX‐1, COX‐2, and PPAR‐γ in the gastric mucosa of children with Helicobacter pylori infection , 2008, Pediatrics international : official journal of the Japan Pediatric Society.

[20]  R. Cukier,et al.  Prostaglandin Endoperoxide H Synthases , 2007, Journal of Biological Chemistry.

[21]  T. Adrian,et al.  Pancreatic Stellate Cells (PSCs) express Cyclooxygenase-2 (COX-2) and pancreatic cancer stimulates COX-2 in PSCs , 2005, Molecular Cancer.

[22]  A. Hopkins,et al.  Navigating chemical space for biology and medicine , 2004, Nature.

[23]  D. Symmons,et al.  The effectiveness of five strategies for the prevention of gastrointestinal toxicity induced by non-steroidal anti-inflammatory drugs: systematic review , 2004, BMJ : British Medical Journal.

[24]  C. Charlier,et al.  Structural approach for COX-2 inhibition. , 2004, Mini reviews in medicinal chemistry.

[25]  Kenneth K Wang,et al.  The "aspirin" of the new millennium: cyclooxygenase-2 inhibitors. , 2000, Mayo Clinic proceedings.

[26]  Vladimir Poroikov,et al.  PASS: prediction of activity spectra for biologically active substances , 2000, Bioinform..

[27]  J. Vane,et al.  Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[28]  P. Isakson,et al.  The discovery and function of COX-2. , 1997, The Journal of rheumatology. Supplement.

[29]  William L. Smith,et al.  Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2* , 1996, The Journal of Biological Chemistry.

[30]  D. Breuer,et al.  Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs. , 1994, The Journal of pharmacology and experimental therapeutics.

[31]  A. Sureda,et al.  Cyclooxygenase-2 inhibitors as a therapeutic target in inflammatory diseases. , 2018, Current medicinal chemistry.

[32]  Mehrdad Hashemi,et al.  Mechanistical Approach Through Discovery of New Generations of Anti Inflammatory Drugs , 2012 .

[33]  D. Kell,et al.  'Metabolite-likeness' as a criterion in the design and selection of pharmaceutical drug libraries. , 2009, Drug discovery today.

[34]  J. Vane,et al.  Cyclooxygenases 1 and 2. , 1998, Annual review of pharmacology and toxicology.