Silencing of protease‐activated receptors attenuates synovitis and cartilage damage following a joint bleed in haemophilic mice

Joint bleeding results in blood‐induced arthropathy. We investigate whether a joint bleed alters protease‐activated receptor (PAR) expression, and whether treatment with small interfering RNA (siRNA) targeted against PAR1–4 attenuates synovitis and cartilage damage.

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