Microgravity, calcium and bone metabolism: a new perspective.

Microgravity-related bone demineralization is investigated. Spaceflight and bedrest studies are discussed which explore changes in bone mineral content, especially calcium. The mechanism of demineralization is examined and the possibility of bone mineral metabolism adapting to the weightlessness environment is considered.

[1]  M. Holick,et al.  Vitamin D and the kidney. , 1987, Kidney international.

[2]  A. Parfitt.  Bone effects of space flight: analysis by quantum concept of bone remodelling. , 1981, Acta astronautica.

[3]  J M Vogel,et al.  Effect of prolonged bed rest on bone mineral. , 1970, Metabolism: clinical and experimental.

[4]  S. Arnaud,et al.  3 – Effects of Inactivity on Bone and Calcium Metabolism , 1986 .

[5]  G. D. Whedon,et al.  Mineral and nitrogen metabolic studies on Skylab orbital space flights. , 1974, Transactions of the Association of American Physicians.

[6]  G. D. Whedon,et al.  Effects of immobilization upon various metabolic and physiologic functions of normal men. , 1948, The American journal of medicine.

[7]  C S Leach,et al.  A study of metabolic balance in crewmembers of Skylab IV. , 1979, Acta astronautica.

[8]  J M Vogel,et al.  Bone mineral measurement: Skylab experiment M-078. , 1975, Acta astronautica.

[9]  J L Kelsey,et al.  Epidemiology of osteoporosis and osteoporotic fractures. , 1985, Epidemiologic reviews.