Tackling neurodegenerative diseases: animal models of Alzheimer’s disease and Parkinson’s disease
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[1] G. Bánhegyi,et al. Physiological functions of presenilins; beyond γ-secretase. , 2014, Current pharmaceutical biotechnology.
[2] C. Haass,et al. Loss of Bace2 in zebrafish affects melanocyte migration and is distinct from Bace1 knock out phenotypes , 2013, Journal of neurochemistry.
[3] James E. DiCarlo,et al. RNA-Guided Human Genome Engineering via Cas9 , 2013, Science.
[4] Le Cong,et al. Multiplex Genome Engineering Using CRISPR/Cas Systems , 2013, Science.
[5] Seung Woo Cho,et al. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease , 2013, Nature Biotechnology.
[6] D. B. Rosemberg,et al. Zebrafish neurotransmitter systems as potential pharmacological and toxicological targets. , 2011, Neurotoxicology and teratology.
[7] M. Ekker,et al. Modeling Neurodegeneration in Zebrafish , 2011, Current neurology and neuroscience reports.
[8] B. de Strooper,et al. Novel research horizons for presenilins and γ-secretases in cell biology and disease. , 2010, Annual review of cell and developmental biology.
[9] E. Rebar,et al. Genome editing with engineered zinc finger nucleases , 2010, Nature Reviews Genetics.
[10] F. Hirth. Drosophila melanogaster in the Study of Human Neurodegeneration , 2010, CNS & neurological disorders drug targets.
[11] C. Haass,et al. Parkin Is Protective against Proteotoxic Stress in a Transgenic Zebrafish Model , 2010, PloS one.
[12] D. Shepherd,et al. Aβ exacerbates the neuronal dysfunction caused by human tau expression in a Drosophila model of Alzheimer's disease , 2010, Experimental Neurology.
[13] W. Sung,et al. Deletion of the WD40 Domain of LRRK2 in Zebrafish Causes Parkinsonism-Like Loss of Neurons and Locomotive Defect , 2010, PLoS genetics.
[14] Leonard I Zon,et al. Swimming into the future of drug discovery: in vivo chemical screens in zebrafish. , 2010, ACS chemical biology.
[15] J. Buxbaum,et al. Enhanced Striatal Dopamine Transmission and Motor Performance with LRRK2 Overexpression in Mice Is Eliminated by Familial Parkinson's Disease Mutation G2019S , 2010, The Journal of Neuroscience.
[16] Joel Ryan,et al. Impaired dopaminergic neuron development and locomotor function in zebrafish with loss of pink1 function , 2010, The European journal of neuroscience.
[17] J. Shulman,et al. Evidence for a common pathway linking neurodegenerative diseases , 2009, Nature Genetics.
[18] S. Pimplikar,et al. Amyloid precursor protein is required for convergent-extension movements during Zebrafish development. , 2009, Developmental biology.
[19] R. Martins,et al. Independent and cooperative action of Psen2 with Psen1 in zebrafish embryos. , 2009, Experimental cell research.
[20] M. Cookson,et al. LRRK2 Modulates Vulnerability to Mitochondrial Dysfunction in Caenorhabditis elegans , 2009, The Journal of Neuroscience.
[21] R. Burke,et al. Mutant LRRK2R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease , 2009, Nature Neuroscience.
[22] R. Nussbaum,et al. Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration , 2009, PloS one.
[23] J. Hardy,et al. The genetics of Parkinson's syndromes: a critical review. , 2009, Current opinion in genetics & development.
[24] S. Hellberg,et al. A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation. , 2009, The Journal of clinical investigation.
[25] M. Chesselet,et al. Bacterial Artificial Chromosome Transgenic Mice Expressing a Truncated Mutant Parkin Exhibit Age-Dependent Hypokinetic Motor Deficits, Dopaminergic Neuron Degeneration, and Accumulation of Proteinase K-Resistant α-Synuclein , 2009, The Journal of Neuroscience.
[26] M. Ohno,et al. Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model , 2009, Neurobiology of Disease.
[27] R. Strauss,et al. Neurotoxic effects induced by the Drosophila amyloid-β peptide suggest a conserved toxic function , 2009, Neurobiology of Disease.
[28] H. Hutter,et al. A Caenorhabditis elegans model of tau hyperphosphorylation: Induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau , 2009, Neurobiology of Aging.
[29] L. Goldstein,et al. Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides. , 2008, Human molecular genetics.
[30] K. Raley-Susman,et al. The invertebrate microtubule-associated protein PTL-1 functions in mechanosensation and development in Caenorhabditis elegans , 2008, Development Genes and Evolution.
[31] Jie Shen,et al. Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress , 2008, Proceedings of the National Academy of Sciences.
[32] M. Chesselet,et al. Olfactory deficits in mice overexpressing human wildtype α‐synuclein , 2008, The European journal of neuroscience.
[33] Fei Liu,et al. Microtubule-associated protein tau in development, degeneration and protection of neurons , 2008, Progress in Neurobiology.
[34] H. Braak,et al. Invited Article: Nervous system pathology in sporadic Parkinson disease , 2008, Neurology.
[35] A. Korczyn. The amyloid cascade hypothesis , 2008, Alzheimer's & Dementia.
[36] I. Hakker,et al. Aβ42 Mutants with Different Aggregation Profiles Induce Distinct Pathologies in Drosophila , 2008, PloS one.
[37] R. Martins,et al. Interference with splicing of Presenilin transcripts has potent dominant negative effects on Presenilin activity. , 2008, Human molecular genetics.
[38] V. Bader,et al. Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage. , 2007, Human molecular genetics.
[39] O. Güntürkün,et al. Non‐motor behavioural impairments in parkin‐deficient mice , 2007, The European journal of neuroscience.
[40] N. Hukriede,et al. Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene , 2007, Nucleic Acids Research.
[41] Ruifeng Lu,et al. Drosophila Overexpressing Parkin R275W Mutant Exhibits Dopaminergic Neuron Degeneration and Mitochondrial Abnormalities , 2007, The Journal of Neuroscience.
[42] Douglas R. Porter,et al. Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice , 2007, Proceedings of the National Academy of Sciences.
[43] J. D. McGaugh,et al. Learning Decreases Aβ*56 and Tau Pathology and Ameliorates Behavioral Decline in 3xTg-AD Mice , 2007, The Journal of Neuroscience.
[44] O. Bandmann,et al. p53‐dependent neuronal cell death in a DJ‐1‐deficient zebrafish model of Parkinson's disease , 2006, Journal of neurochemistry.
[45] Y. Christen,et al. Amyloid-β-Induced Pathological Behaviors Are Suppressed by Ginkgo biloba Extract EGb 761 and Ginkgolides in Transgenic Caenorhabditis elegans , 2006, The Journal of Neuroscience.
[46] M. Ohno,et al. Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation , 2006, The Journal of Neuroscience.
[47] C. Link. C. elegans models of age-associated neurodegenerative diseases: Lessons from transgenic worm models of Alzheimer’s disease , 2006, Experimental Gerontology.
[48] Hui Zheng,et al. Molecular Neurodegeneration BioMed Central Review The amyloid precursor protein: beyond amyloid , 2006 .
[49] Sunhong Kim,et al. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin , 2006, Nature.
[50] Changan Jiang,et al. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin , 2006, Nature.
[51] Huaxi Xu,et al. Pathological and physiological functions of presenilins , 2006, Molecular Neurodegeneration.
[52] Mark Bowlby,et al. Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[53] M. Gallagher,et al. A specific amyloid-β protein assembly in the brain impairs memory , 2006, Nature.
[54] Stephen T. C. Wong,et al. Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen‐2) demonstrate excessive p53‐dependent apoptosis and neuronal loss , 2006, Journal of neurochemistry.
[55] J. Trojanowski,et al. Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications. , 2006, Annual review of pathology.
[56] T. Iwatsubo,et al. Familial Parkinson Mutant α-Synuclein Causes Dopamine Neuron Dysfunction in Transgenic Caenorhabditis elegans* , 2006, Journal of Biological Chemistry.
[57] D. Price,et al. Parkinson's Disease α-Synuclein Transgenic Mice Develop Neuronal Mitochondrial Degeneration and Cell Death , 2006, The Journal of Neuroscience.
[58] Michela Gallagher,et al. A specific amyloid-beta protein assembly in the brain impairs memory. , 2006, Nature.
[59] D. Price,et al. Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. , 2006, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[60] Richard M. Page,et al. Intraneuronal Aβ, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer’s disease , 2005, Neuroscience.
[61] T. Hoppe,et al. A Caenorhabditis elegans Parkin mutant with altered solubility couples alpha-synuclein aggregation to proteotoxic stress. , 2005, Human molecular genetics.
[62] K. Gengyo-Ando,et al. Progressive neurodegeneration in C. elegans model of tauopathy , 2005, Neurobiology of Disease.
[63] Andrew B West,et al. Molecular pathophysiology of Parkinson's disease. , 2005, Annual review of neuroscience.
[64] Tiffany Mathews,et al. Age-dependent Motor Deficits and Dopaminergic Dysfunction in DJ-1 Null Mice* , 2005, Journal of Biological Chemistry.
[65] David S. Park,et al. Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[66] J. D. McGaugh,et al. Intraneuronal Aβ Causes the Onset of Early Alzheimer’s Disease-Related Cognitive Deficits in Transgenic Mice , 2005, Neuron.
[67] E. Masliah,et al. Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease , 2005, Science.
[68] P. Calabresi,et al. Nigrostriatal Dopaminergic Deficits and Hypokinesia Caused by Inactivation of the Familial Parkinsonism-Linked Gene DJ-1 , 2005, Neuron.
[69] N. Shahani,et al. Tau alteration and neuronal degeneration in tauopathies: mechanisms and models. , 2005, Biochimica et biophysica acta.
[70] Jonathan Salcedo,et al. Early and Progressive Sensorimotor Anomalies in Mice Overexpressing Wild-Type Human α-Synuclein , 2004, The Journal of Neuroscience.
[71] Kurt Bürki,et al. Aβ is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis , 2004, Nature Neuroscience.
[72] M. Konsolaki,et al. A model for studying Alzheimer's Aβ42-induced toxicity in Drosophila melanogaster , 2004, Molecular and Cellular Neuroscience.
[73] F. Bloom,et al. Selective vulnerability of dentate granule cells prior to amyloid deposition in PDAPP mice: digital morphometric analyses. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[74] Ann-Shyn Chiang,et al. Dissecting the pathological effects of human Aβ40 and Aβ42 in Drosophila: A potential model for Alzheimer's disease , 2004 .
[75] R. Nitsch,et al. Age-Dependent Neurodegeneration and Alzheimer-Amyloid Plaque Formation in Transgenic Drosophila , 2004, The Journal of Neuroscience.
[76] Jesus Avila,et al. Role of tau protein in both physiological and pathological conditions. , 2004, Physiological reviews.
[77] C. Haass. Take five—BACE and the γ‐secretase quartet conduct Alzheimer's amyloid β‐peptide generation , 2004 .
[78] C. Haass. Take five--BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation. , 2004, The EMBO journal.
[79] M. Chesselet,et al. Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein. , 2004, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[80] Ann-Shyn Chiang,et al. Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[81] F. LaFerla,et al. Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer’s disease , 2003, Neurobiology of Aging.
[82] Janel O. Johnson,et al. α-Synuclein Locus Triplication Causes Parkinson's Disease , 2003, Science.
[83] M. Lardelli,et al. Developmental control of Presenilin1 expression, endoproteolysis, and interaction in zebrafish embryos. , 2003, Experimental cell research.
[84] D. Holtzman,et al. Apolipoprotein E Markedly Facilitates Age-Dependent Cerebral Amyloid Angiopathy and Spontaneous Hemorrhage in Amyloid Precursor Protein Transgenic Mice , 2003, The Journal of Neuroscience.
[85] M. Mattson,et al. Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles Intracellular Aβ and Synaptic Dysfunction , 2003, Neuron.
[86] Bin Zhang,et al. Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[87] V. Buchman,et al. Part II: α-synuclein and its molecular pathophysiological role in neurodegenerative disease , 2003, Neuropharmacology.
[88] R. Blakely,et al. Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human α‐synuclein , 2003, Journal of neurochemistry.
[89] F. Bloom,et al. Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[90] B. Strooper,et al. Aph-1, Pen-2, and Nicastrin with Presenilin Generate an Active γ-Secretase Complex , 2003, Neuron.
[91] Russell E Jacobs,et al. Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: A magnetic resonance microscopy and stereologic analysis , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[92] V. Buchman,et al. Part II: alpha-synuclein and its molecular pathophysiological role in neurodegenerative disease. , 2003, Neuropharmacology.
[93] B. de Strooper,et al. Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex. , 2003, Neuron.
[94] J. Wood,et al. Transgenic zebrafish model of neurodegeneration , 2002, Journal of neuroscience research.
[95] T. Hashikawa,et al. Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[96] Nancy A. Jenkins,et al. Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[97] Makoto Hashimoto,et al. Differential neuropathological alterations in transgenic mice expressing α‐synuclein from the platelet‐derived growth factor and Thy‐1 promoters , 2002, Journal of neuroscience research.
[98] D. Geschwind,et al. Human Wild-Type Tau Interacts with wingless Pathway Components and Produces Neurofibrillary Pathology in Drosophila , 2002, Neuron.
[99] Koji Abe,et al. Amyloid cored plaques in Tg2576 transgenic mice are characterized by giant plaques, slightly activated microglia, and the lack of paired helical filament-typed, dystrophic neurites , 2002, Virchows Archiv.
[100] D. P. Thompson,et al. Caenorhabditis elegans: how good a model for veterinary parasites? , 2001, Veterinary parasitology.
[101] R. Nitsch,et al. Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils , 2001, Science.
[102] J. Hardy,et al. Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP , 2001, Science.
[103] S. Turner,et al. Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695* , 2001, The Journal of Biological Chemistry.
[104] Joshua M. Shulman,et al. Tauopathy in Drosophila: Neurodegeneration Without Neurofibrillary Tangles , 2001, Science.
[105] David H. Hall,et al. Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34 , 2001, Neurobiology of Aging.
[106] M. Staufenbiel,et al. Spontaneous Hemorrhagic Stroke in a Mouse Model of Cerebral Amyloid Angiopathy , 2001, The Journal of Neuroscience.
[107] J. Trojanowski,et al. Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice. , 2001, The American journal of pathology.
[108] R. Nitsch,et al. Tau Filament Formation in Transgenic Mice Expressing P301L Tau* , 2001, The Journal of Biological Chemistry.
[109] Darren W. Williams,et al. Tau and tau reporters disrupt central projections of sensory neurons in Drosophila , 2000, The Journal of comparative neurology.
[110] Guiquan Chen,et al. A learning deficit related to age and β-amyloid plaques in a mouse model of Alzheimer's disease , 2000, Nature.
[111] R. Nitsch,et al. In Vivo Analysis of Wild‐type and FTDP‐17 Tau Transgenic Mice , 2000, Annals of the New York Academy of Sciences.
[112] Hsiao-Wen Chen,et al. Unusual spectral energy distribution of a galaxy previously reported to be at redshift 6.68 , 2000, Nature.
[113] M. Citron,et al. Aβ-Generating Enzymes Recent Advances in β- and γ-Secretase Research , 2000, Neuron.
[114] Christian Haass,et al. Subcellular Localization of Wild-Type and Parkinson's Disease-Associated Mutant α-Synuclein in Human and Transgenic Mouse Brain , 2000, The Journal of Neuroscience.
[115] Pico Caroni,et al. Neuropathology in Mice Expressing Human α-Synuclein , 2000, The Journal of Neuroscience.
[116] R. A. Crowther,et al. Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein , 2000, Acta Neuropathologica.
[117] S. Paul,et al. Neuroanatomical Abnormalities in Behaviorally Characterized APPV717F Transgenic Mice , 2000, Neurobiology of Disease.
[118] P. Davies,et al. Characterization of Pathology in Transgenic Mice Over-Expressing Human Genomic and cDNA Tau Transgenes , 2000, Neurobiology of Disease.
[119] C. Haass,et al. Presenilin-1 differentially facilitates endoproteolysis of the β-amyloid precursor protein and Notch , 2000, Nature Cell Biology.
[120] W. Bender,et al. A Drosophila model of Parkinson's disease , 2000, Nature.
[121] L. Mucke,et al. Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. , 2000, Science.
[122] Jada Lewis. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein , 2000, Nature Genetics.
[123] P. Caroni,et al. Neuropathology in mice expressing human alpha-synuclein. , 2000, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[124] M. Citron,et al. Abeta-generating enzymes: recent advances in beta- and gamma-secretase research. , 2000, Neuron.
[125] H. Geerts,et al. Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein. , 1999, The American journal of pathology.
[126] B. Sommer,et al. Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[127] Cori Bargmann. Neurobiology of the Caenorhabditis elegans genome. , 1998, Science.
[128] Ronald C. Petersen,et al. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 , 1998, Nature.
[129] J. Hardy,et al. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes , 1998, Nature Medicine.
[130] B. Sommer,et al. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[131] Robert L. Nussbaum,et al. Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease , 1997 .
[132] E. Masliah,et al. Neurodegeneration and cognitive impairment in apoE-deficient mice is ameliorated by infusion of recombinant apoE , 1997, Brain Research.
[133] S E Ide,et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. , 1997, Science.
[134] Weiming Xia,et al. Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice , 1997, Nature Medicine.
[135] J. Ahringer,et al. PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans. , 1996, Journal of cell science.
[136] Allan I. Levey,et al. Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo , 1996, Neuron.
[137] J. Hardy,et al. Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1 , 1996, Nature.
[138] S. Younkin,et al. Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice , 1996, Science.
[139] J. McDermott,et al. ptl-1, a Caenorhabditis elegans gene whose products are homologous to the tau microtubule-associated proteins. , 1996, Biochemistry.
[140] A. Roses,et al. Neurodegeneration in the Central Nervous System of apoE-Deficient Mice , 1995, Experimental Neurology.
[141] D. Michaelson,et al. Memory deficits and cholinergic impairments in apolipoprotein E-deficient mice , 1995, Neuroscience Letters.
[142] C. Link,et al. Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[143] G. Dawson,et al. β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity , 1995, Cell.
[144] L. Mucke,et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein , 1995, Nature.
[145] A. M. Saunders,et al. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease , 1994, Nature Genetics.
[146] J. Haines,et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. , 1993, Science.
[147] M. Pericak-Vance,et al. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[148] M A Pericak-Vance,et al. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. , 1993, Neurology.
[149] D. Selkoe. The molecular pathology of Alzheimer's disease , 1991, Neuron.