Ensembl 2018

Abstract The Ensembl project has been aggregating, processing, integrating and redistributing genomic datasets since the initial releases of the draft human genome, with the aim of accelerating genomics research through rapid open distribution of public data. Large amounts of raw data are thus transformed into knowledge, which is made available via a multitude of channels, in particular our browser (http://www.ensembl.org). Over time, we have expanded in multiple directions. First, our resources describe multiple fields of genomics, in particular gene annotation, comparative genomics, genetics and epigenomics. Second, we cover a growing number of genome assemblies; Ensembl Release 90 contains exactly 100. Third, our databases feed simultaneously into an array of services designed around different use cases, ranging from quick browsing to genome-wide bioinformatic analysis. We present here the latest developments of the Ensembl project, with a focus on managing an increasing number of assemblies, supporting efforts in genome interpretation and improving our browser.

Astrid Gall | Alessandro Vullo | Jane Loveland | Matthew R. Laird | Daniel R. Zerbino | Laurent Gil | Matthieu Muffato | Zhicheng Liu | Jonathan M. Mudge | Daniel Barrell | Andrew D. Yates | William M. McLaren | Magali Ruffier | Kieron R. Taylor | Helen Schuilenburg | Michael Nuhn | Paul Flicek | Daniel M. Staines | Brandon Walts | Thomas Juettemann | Sarah E. Hunt | Konstantinos Billis | Benjamin Moore | Emily Perry | Bronwen L. Aken | Carlos García-Girón | Thibaut Hourlier | Fergal J. Martin | Daniel N. Murphy | Amonida Zadissa | Carla A. Cummins | Stephen J. Trevanion | Adam Frankish | Daniel Sheppard | Mateus Patricio | Thomas Maurel | Victoria Newman | Chuang Kee Ong | Helen Sparrow | Nicholas Langridge | Premanand Achuthan | Anja Thormann | Anne Parker | Fiona Cunningham | Wasiu A. Akanni | M. Ridwan Amode | Sophie H. Janacek | Ilias Lavidas | Harpreet Singh Riat | Osagie G. Izuogu | Myrto Kostadima | Jyothish Bhai | Leanne Haggerty | Erin Haskell | Denye Ogeh | Denye N. Ogeh | Leo Gordon | Jimmy Kiang To | Fergal J. Martin | A. Frankish | D. Barrell | A. Zadissa | F. Cunningham | W. McLaren | P. Flicek | D. Zerbino | S. Hunt | Anne Parker | S. Trevanion | Konstantinos Billis | Magali Ruffier | H. Riat | A. Thormann | Thomas Juettemann | Daniel Sheppard | Ilias Lavidas | M. Nuhn | Emily Perry | M. Amode | C. García-Girón | Leo Gordon | Thibaut Hourlier | Thomas Maurel | Mateus Patricio | K. Taylor | Alessandro Vullo | Matthieu Muffato | J. Loveland | H. Schuilenburg | Brandon Walts | Zhicheng Liu | B. Moore | D. Staines | P. Achuthan | C. Ong | Erin Haskell | A. Gall | Nicholas Langridge | S. Hunt | Leanne Haggerty | Jyothish Bhai | V. Newman | Helen Sparrow | Myrto A. Kostadima | C. G. Girón | Denye Ogeh | Laurent Gil | Fiona Cunningham | J. To | A. Vullo | Jimmy To | M. Laird | Helen Schuilenburg

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