Meeting Summary: 2019 James W. Freston Conference: Food at the Intersection of Gut Health and Disease.

Financial Disclosures Gerard Mullin, MD, AGAF -Johns Hopkins Conflicts of Interest: NO, financial relationship with a commercial interest William Chey MD, AGAF -University of Michigan Health System Relevant Disclosures: Consultant: Biomerica, Commonwealth Diagnostics, IM Health Sciences, QOL Medical, Ritter, Research Grants: Biomerica, Commonwealth Diagnostics, Nestle, QOL Medical, Zespri Ashwin Ananthakrishan MBBS, MPH -Massachusetts General Hospital Conflicts of Interest: Research Support from Pfizer Bibiana Garcia-Bailo, MSc, PhD -University of Toronto and Nutrigenomix Inc. Conflicts of Interest: Employee of Nutrigenomix, Inc. Evan Dellon MD, MPH, AGAF -University of North Carolina School of Medicine Conflicts of Interest: Consultant for Adare, Alivio, Allakos, AstraZeneca, Banner, Calypso, Celgene/Receptos, Enumeral, EsoCap, Gossamer Bio, GSK, Regeneron, Robarts and Shire. Research support from Adare, Allakos, Celgene/Receptos, GSK, Regeneron and Shire. Education grant from Banner and Holoclara. John DiBaise, MD -Mayo Clinic Conflicts of Interest: Consultant for Allena Pharmaceuticals. Advisory board member for Zealand Pharmaceuticals as well as Coram/ CVS. Book royalties from McGraw-Hill, Springer and CRC Press. Alessio Fasano, MD -Massachusetts General Hospital for Children Conflicts of Interest: Consultant for Inova Diagnostics, Innovate Biopharma and uBiome. Advisory board member for Axial Biotherapeutics. Research support from Takeda. Speaking agreement from Mead Johnson Nutrition and stockholder of Alba Therapeutics. Emily Haller, MS, RDN -University of Michigan Health System Conflicts of Interest: NO financial relationship with a commercial interest Matthew J. Hamilton, MD -Brigham and Women’s Hospital Conflicts of Interest: Consultant for Takeda, Pfizer, Allakos and AbbVie Sam Klein, MD -Washington University School Of Medicine Conflicts of Interest: Consultant for Pfizer and NovoNordisk. Research support from Merck and Janssen. Scientific Advisory Board for Dannon/Yakult and Merck. Stockholder of Aspire Bariatrics. Benjamin Lebwohl, MD, AGAF -Columbia University Medical Center Conflicts of Interest: Consultant for Takeda and Innovate Biopharmaceuticals. John Leung, MD -Tuft University /New England Medical Center Conflicts of Interest: Consultant for Shire. James Lewis, MD, MSCE, AGAF -University of Pennsylvania Conflicts of Interest: Consultant for Crohn’s & Colitis Foundation, IBD Plexus, Samsung Bioepis, Pfizer Gilead, UCB, Bridge Biotherapeutics, Bristo-Myers Squibb, Arena Pharmaceuticals. Research support from Takeda, Janssen, Nestle Health Science and AbbVie. Gerard Mullin, MD, AGAF -Johns Hopkins Conflicts of Interest: NO, financial relationship with a commercial interest Linda Nguyen, MD, AGAF -Stanford University School of Medicine Conflicts of Interest: Consult for Allergan, Ironwood and Nevro. Research support from Vanda. John Pandolfino, MD, AGAF -Northwestern University Conflicts of Interest: Consultant for Medtronic, Diversatek, Ironwood and Tora-Ethicon. Research support from Impleo. Salary and speaking honorarium from Medtronic/Crospon for EndoFLIP. Stocks from Cropon and Trmedyne Laser. Carol Rees Parrish MS, RDN -University of Virginia Health System Conflicts of Interest: Honoraria from Shire and Takeda for paid publications as well as from Shire for speaking. Kate Scarlata, RDN -Boston University Conflicts of Interest: Consulting for FODY Food Company (a low FODMAP Company), Campbell Soup, Rachel Pauls Food, Casa de Sante Foods and Nestle. Sponsored talks at Nutrition Events Jan Tack, MD PhD -KU Leuven Conflicts of Interest: Consultant for AlfaSigma, AlfaWassermann, Allergan, Alnylam, Arena, Christian Hansen, Danone, EA Pharma, Grünenthal, Ironwood, Kyowa Kirin, Menarini, Mylan, Neurogastrx, Neutec, Novartis, Noventure, Nutricia, Shionogi, Shire, Takeda, Theravance, Tramedico, Truvion, Tsumura, Zealand and Zeria. Research Support from: Shire, Tsumura, Abbott, Allergan, Ironwood, Kyowa Kirin, Menarini, Mylan, Novartis, Shire, Takeda, Truvion, Zeria Jeanetta Frye, MD -University of Virginia Conflicts of Interest: Consultant to Isothrive Kimberely Harer, MD -University of Michigan Conflicts of Interest: NO, financial relationship with a commercial interest HHS Public Access Author manuscript Gastroenterology. Author manuscript; available in PMC 2021 July 01.

[1]  C. Weiler Mast Cell Activation Syndrome: Tools for Diagnosis and Differential Diagnosis , 2020 .

[2]  J. Muir,et al.  Implementation of the low FODMAP diet in functional gastrointestinal symptoms: A real‐world experience , 2020, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[3]  J. Tack,et al.  Duodenal nutrient exposure contributes to enhancing gastric accommodation , 2019, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[4]  J. Bielawski,et al.  Crohn's Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial. , 2019, Gastroenterology.

[5]  P. Valent,et al.  Doctor, I Think I Am Suffering from MCAS: Differential Diagnosis and Separating Facts from Fiction. , 2019, The journal of allergy and clinical immunology. In practice.

[6]  A. Rundle,et al.  Detection of Gluten in Gluten-Free Labeled Restaurant Food: Analysis of Crowd-Sourced Data , 2019, The American journal of gastroenterology.

[7]  A. Friedman,et al.  A Review of the Dermatologic Symptoms of Idiopathic Mast Cell Activation Syndrome , 2019, Journal of Drugs in Dermatology.

[8]  G. Mullin,et al.  The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data , 2019, BMC Complementary and Alternative Medicine.

[9]  B. Kuo,et al.  Gastroparesis and Functional Dyspepsia: A Blurring Distinction of Pathophysiology and Treatment , 2019, Journal of Neurogastroenterology and Motility.

[10]  G. Mullin,et al.  Dietary interventions for induction and maintenance of remission in inflammatory bowel disease. , 2019, The Cochrane database of systematic reviews.

[11]  P. Moayyedi,et al.  Systematic review with meta‐analysis: the efficacy of prebiotics, probiotics, synbiotics and antibiotics in irritable bowel syndrome , 2018, Alimentary pharmacology & therapeutics.

[12]  P. Moayyedi,et al.  A Systematic Review and Meta‐Analysis Evaluating the Efficacy of a Gluten‐Free Diet and a Low FODMAPS Diet in Treating Symptoms of Irritable Bowel Syndrome , 2018, The American Journal of Gastroenterology.

[13]  V. Isakov,et al.  Fiber-enriched diet helps to control symptoms and improves esophageal motility in patients with non-erosive gastroesophageal reflux disease , 2018, World journal of gastroenterology.

[14]  A. Levine,et al.  Evolving role of diet in the pathogenesis and treatment of inflammatory bowel diseases , 2018, Gut.

[15]  C. Buss,et al.  Effects of very low calorie diets on liver size and weight loss in the preoperative period of bariatric surgery: a systematic review. , 2017, Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery.

[16]  David M. Liebovitz,et al.  The Reflux Improvement and Monitoring (TRIM) Program Is Associated With Symptom Improvement and Weight Reduction for Patients With Obesity and Gastroesophageal Reflux Disease , 2018, The American Journal of Gastroenterology.

[17]  G. Mullin,et al.  Therapeutic food claims: a global perspective , 2017, Current opinion in clinical nutrition and metabolic care.

[18]  J. DiBaise,et al.  Managing the Adult Patient With Short Bowel Syndrome. , 2017, Gastroenterology & hepatology.

[19]  A. Ananthakrishnan,et al.  Systematic review with meta‐analysis: enteral nutrition therapy for the induction of remission in paediatric Crohn's disease , 2017, Alimentary pharmacology & therapeutics.

[20]  A. Fasano,et al.  Celiac Disease and Nonceliac Gluten Sensitivity: A Review , 2017, JAMA.

[21]  Kristle L. Lynch,et al.  Can We Use Diet to Effectively Treat Esophageal Disease? A Review of the Current Literature , 2017, Current Gastroenterology Reports.

[22]  G. Burazeri,et al.  Adherence to a predominantly Mediterranean diet decreases the risk of gastroesophageal reflux disease: a cross-sectional study in a South Eastern European population. , 2016, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

[23]  J. Mclaughlin,et al.  Dietary Practices and Beliefs in Patients with Inflammatory Bowel Disease , 2016, Inflammatory bowel diseases.

[24]  F. Chan,et al.  Rome IV - Gastroduodenal Disorders. , 2016, Gastroenterology.

[25]  D. D. de Luis,et al.  Effects of a High-Protein/Low-Carbohydrate Diet versus a Standard Hypocaloric Diet on Weight and Cardiovascular Risk Factors: Role of a Genetic Variation in the rs9939609 FTO Gene Variant , 2015, Lifestyle Genomics.

[26]  M. Bardella,et al.  Diagnosis of gluten related disorders: Celiac disease, wheat allergy and non-celiac gluten sensitivity. , 2015, World journal of gastroenterology.

[27]  Wen Guo The Health Professional's Guide to Gastrointestinal Nutrition , 2015 .

[28]  R. Baldassano,et al.  Diet in the pathogenesis and treatment of inflammatory bowel diseases. , 2015, Gastroenterology.

[29]  A. Thorell,et al.  Weight loss before bariatric surgery and postoperative complications: data from the Scandinavian Obesity Registry (SOReg). , 2015, Annals of surgery.

[30]  Omry Koren,et al.  Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome , 2015, Nature.

[31]  S. Crowe,et al.  Food allergy and food intolerance. , 2015, World review of nutrition and dietetics.

[32]  G. Nguyen,et al.  Practices and attitudes toward complementary and alternative medicine in inflammatory bowel disease: a survey of gastroenterologists , 2014, Journal of complementary & integrative medicine.

[33]  Mark Ellrichmann,et al.  Confocal endomicroscopy shows food-associated changes in the intestinal mucosa of patients with irritable bowel syndrome. , 2014, Gastroenterology.

[34]  Alissa L Allen,et al.  Do polymorphisms in chemosensory genes matter for human ingestive behavior? , 2013, Food quality and preference.

[35]  J. Tack,et al.  Food and Symptom Generation in Functional Gastrointestinal Disorders: Physiological Aspects , 2013, The American Journal of Gastroenterology.

[36]  E. Dellon,et al.  Clinical Guideline : Evidenced Based Approach to the Diagnosis and Management of Esophageal Eosinophilia and Eosinophilic Esophagitis ( EoE ) , 2013 .

[37]  A. El-Sohemy,et al.  Coffee, CYP1A2 genotype, and risk of myocardial infarction. , 2006, JAMA.

[38]  S. Bischoff,et al.  Gastrointestinal food allergy: new insights into pathophysiology and clinical perspectives. , 2005, Gastroenterology.