Structure-activity relationships of substituted benzothiophene-anthranilamide factor Xa inhibitors.
暂无分享,去创建一个
D. Davey | K. Eagen | M. Morrissey | G. Phillips | Yuo-Ling Chou | M. Kochanny | Lan Trinh | Monica J Kochanny | Michael M Morrissey | Brian D Griedel | Rushad Karanjawala | Karna L Sacchi | Kenneth J Shaw | Shung C Wu | Dao Lentz | L. Trinh | K. Shaw | B. Griedel | Rushad E. Karanjawala | A. Liang | K. L. Sacchi | David D Davey | Keith A Eagen | Gary B Phillips | Amy M Liang | Shung C. Wu | Dao Lentz | Y. Chou
[1] H. Ishihara,et al. DX-9065a, an Orally Active, Specific Inhibitor of Factor Xa, Inhibits Thrombosis without Affecting Bleeding Time in Rats , 1995, Thrombosis and Haemostasis.
[2] P. Sprengeler,et al. Perspectives on factor Xa inhibition. , 2001, Current medicinal chemistry.
[3] D. Smith,et al. Tick anticoagulant peptide: kinetic analysis of the recombinant inhibitor with blood coagulation factor Xa. , 1990, Biochemistry.
[4] P. Sprengeler,et al. Neutral inhibitors of the serine protease factor Xa. , 2001, Bioorganic & medicinal chemistry letters.
[5] J. Vacca. New advances in the discovery of thrombin and factor Xa inhibitors. , 2000, Current opinion in chemical biology.
[6] S. Hanson,et al. Antithrombotic Benefits and Hemorrhagic Risks of Direct Thrombin Antagonists , 1995, Thrombosis and Haemostasis.
[7] P. Sanderson. Chapter 8. Anticoagulants: Inhibitors of thrombin and factor Xa , 2001 .
[8] J. Vacca,et al. Potent noncovalent thrombin inhibitors that utilize the unique amino acid D-dicyclohexylalanine in the P3 position. Implications on oral bioavailability and antithrombotic efficacy. , 1997, Journal of medicinal chemistry.
[9] W. R. Ewing,et al. PROGRESS IN THE DESIGN OF INHIBITORS OF COAGULATION FACTOR XA , 1999 .
[10] Kenneth G. Mann,et al. Surface-dependent reactions of the vitamin K-dependent enzyme complexes , 1990 .
[11] B. Zhu,et al. Chapter 9. Factor Xa inhibitors: Recent advances in anticoagulant agents , 2000 .
[12] J F Morrison,et al. Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors. , 1969, Biochimica et biophysica acta.
[13] J. A. Kyle,et al. N(2)-Aroylanthranilamide inhibitors of human factor Xa. , 2000, Journal of medicinal chemistry.
[14] J. A. Kyle,et al. 1,2-Dibenzamidobenzene inhibitors of human factor Xa. , 2000, Journal of medicinal chemistry.
[15] J. T. Metz,et al. Non-amidine-containing 1,2-dibenzamidobenzene inhibitors of human factor Xa with potent anticoagulant and antithrombotic activity. , 2000, Journal of medicinal chemistry.
[16] P. Walsh,et al. Components and Assembly of the Factor X Activating Complex , 1992, Seminars in thrombosis and hemostasis.
[17] P. Coleman,et al. Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates. , 1981, Methods in enzymology.