RIPK1 protects hepatocytes from death in Fas-induced hepatitis

[1]  M. Bertrand,et al.  RIPK1 protects hepatocytes from Kupffer cells-mediated TNF-induced apoptosis in mouse models of PAMP-induced hepatitis. , 2017, Journal of hepatology.

[2]  M. Bertrand,et al.  RIPK1 protects from TNF-α-mediated liver damage during hepatitis , 2016, Cell Death & Disease.

[3]  Yong-mei Song,et al.  Knockdown of RIPK1 Markedly Exacerbates Murine Immune-Mediated Liver Injury through Massive Apoptosis of Hepatocytes, Independent of Necroptosis and Inhibition of NF-κB , 2016, The Journal of Immunology.

[4]  G. Kollias,et al.  Opposing role of tumor necrosis factor receptor 1 signaling in T cell–mediated hepatitis and bacterial infection in mice , 2016, Hepatology.

[5]  J. Silke,et al.  The diverse role of RIP kinases in necroptosis and inflammation , 2015, Nature Immunology.

[6]  P. Vandenabeele,et al.  Necroptosis and its role in inflammation , 2015, Nature.

[7]  D. Green,et al.  RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3 , 2014, Cell.

[8]  Junying Yuan,et al.  Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death , 2013, Nature Reviews Molecular Cell Biology.

[9]  L. Galluzzi,et al.  Decoding cell death signals in liver inflammation. , 2013, Journal of hepatology.

[10]  C. Trautwein,et al.  TRAIL but not FasL and TNFα, regulates IL‐33 expression in murine hepatocytes during acute hepatitis , 2012, Hepatology.

[11]  Michael Karin,et al.  A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. , 2012, Gastroenterology.

[12]  F. Tacke,et al.  Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury. , 2011, Gastroenterology.

[13]  M. Bertrand,et al.  TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members , 2011, Cell Death and Disease.

[14]  D. Vaux,et al.  In TNF-stimulated Cells, RIPK1 Promotes Cell Survival by Stabilizing TRAF2 and cIAP1, which Limits Induction of Non-canonical NF-κB and Activation of Caspase-8* , 2011, The Journal of Biological Chemistry.

[15]  G. Gores,et al.  Hepatocyte death: a clear and present danger. , 2010, Physiological reviews.

[16]  D. Vaux,et al.  RIPK1 is not essential for TNFR1-induced activation of NF-κB , 2010, Cell Death and Differentiation.

[17]  S. Fulda,et al.  Histone deacetylase inhibitors cooperate with IFN-γ to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8 , 2009, Oncogene.

[18]  Xiaodong Wang,et al.  TNF-α Induces Two Distinct Caspase-8 Activation Pathways , 2008, Cell.

[19]  P. Schneider,et al.  TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality. , 2006, The Journal of clinical investigation.

[20]  Toshinori Nakayama,et al.  Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[21]  Z. Tian,et al.  Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS. , 2002, The Journal of clinical investigation.

[22]  S. Fulda,et al.  IFNγ sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway , 2002, Oncogene.

[23]  D. Yousem,et al.  A clear and present danger? , 2001, AJNR. American journal of neuroradiology.

[24]  M. Kelliher,et al.  The Death Domain Kinase RIP Is Essential for TRAIL (Apo2L)-Induced Activation of IκB Kinase and c-Jun N-Terminal Kinase , 2000, Molecular and Cellular Biology.

[25]  L. Kaer,et al.  Critical contribution of liver natural killer T cells to a murine model of hepatitis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[26]  M. Taniguchi,et al.  Augmentation of Vα14 Nkt Cell–Mediated Cytotoxicity by Interleukin 4 in an Autocrine Mechanism Resulting in the Development of Concanavalin a–Induced Hepatitis , 2000, The Journal of experimental medicine.

[27]  A. Strasser,et al.  Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L). , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[28]  G. Wanner,et al.  Inhibition of caspase activity prevents CD95‐mediated hepatic microvascular perfusion failure and restores Kupffer cell clearance capacity , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[29]  C. Rauch,et al.  Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo , 1999, Nature Medicine.

[30]  M. Manns,et al.  Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in mice. , 1998, Gastroenterology.

[31]  Stefan Grimm,et al.  The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal , 1998 .

[32]  L. Hood,et al.  Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. , 1997, Immunity.

[33]  K. Takeda,et al.  Contribution of Fas ligand to T cell-mediated hepatic injury in mice. , 1997, Gastroenterology.

[34]  Y. Iwakura,et al.  Suppression of concanavalin A-induced hepatitis in IFN-gamma(-/-) mice, but not in TNF-alpha(-/-) mice: role for IFN-gamma in activating apoptosis of hepatocytes. , 1997, Journal of immunology.

[35]  T. Akaike,et al.  Concanavalin A induces perforin‐mediated but not Fas‐mediated hepatic injury , 1996, Hepatology.

[36]  H. Fujiwara,et al.  Critical involvement of interferon γ in the pathogenesis of T‐cell activation‐associated hepatitis and regulatory mechanisms of interleukin‐6 for the manifestations of hepatitis , 1996, Hepatology.

[37]  D. Goeddel,et al.  TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. , 1996, Immunity.

[38]  P. Leder,et al.  RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death , 1995, Cell.

[39]  S. Nagata,et al.  Lethal effect of the anti-Fas antibody in mice , 1993, Nature.

[40]  T. Luedde,et al.  RIPK1 suppresses a TRAF2-dependent pathway to liver cancer , 2017 .

[41]  YOUHAI H. Chen,et al.  Critical roles of TRAIL in hepatic cell death and hepatic inflammation. , 2004, The Journal of clinical investigation.

[42]  P. Leder,et al.  The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. , 1998, Immunity.

[43]  M. Leist,et al.  The 55-kD Tumor Necrosis Factor Receptor and CD95 Independently Signal Murine Hepatocyte Apoptosis and Subsequent Liver Failure , 1996, Molecular medicine.