A Wearable Smartphone-Based Platform for Real-Time Cardiovascular Disease Detection Via Electrocardiogram Processing

Cardiovascular disease (CVD) is the single leading cause of global mortality and is projected to remain so. Cardiac arrhythmia is a very common type of CVD and may indicate an increased risk of stroke or sudden cardiac death. The ECG is the most widely adopted clinical tool to diagnose and assess the risk of arrhythmia. ECGs measure and display the electrical activity of the heart from the body surface. During patients' hospital visits, however, arrhythmias may not be detected on standard resting ECG machines, since the condition may not be present at that moment in time. While Holter-based portable monitoring solutions offer 24-48 h ECG recording, they lack the capability of providing any real-time feedback for the thousands of heart beats they record, which must be tediously analyzed offline. In this paper, we seek to unite the portability of Holter monitors and the real-time processing capability of state-of-the-art resting ECG machines to provide an assistive diagnosis solution using smartphones. Specifically, we developed two smartphone-based wearable CVD-detection platforms capable of performing real-time ECG acquisition and display, feature extraction, and beat classification. Furthermore, the same statistical summaries available on resting ECG machines are provided.

[1]  E.T. Lim,et al.  Cellular phone based online ECG processing for ambulatory and continuous detection , 2007, 2007 Computers in Cardiology.

[2]  P. Hamilton,et al.  Open source ECG analysis , 2002, Computers in Cardiology.

[3]  E. Gonzalez-Parada,et al.  A PDA-based portable wireless ECG monitor for medical personal area networks , 2006, MELECON 2006 - 2006 IEEE Mediterranean Electrotechnical Conference.

[4]  Zhanpeng Jin,et al.  Predicting cardiovascular disease from real-time electrocardiographic monitoring: An adaptive machine learning approach on a cell phone , 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[5]  Arantza Illarramendi,et al.  Real-time classification of ECGs on a PDA , 2005, IEEE Transactions on Information Technology in Biomedicine.

[6]  D. Mozaffarian,et al.  Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. , 2009, Circulation.

[7]  Willis J. Tompkins,et al.  Quantitative Investigation of QRS Detection Rules Using the MIT/BIH Arrhythmia Database , 1986, IEEE Transactions on Biomedical Engineering.

[8]  W. Chung,et al.  A Cell Phone Based Health Monitoring System with Self Analysis Processor using Wireless Sensor Network Technology , 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[9]  Myeong-Chan Cho,et al.  Biomedical Digital Assistant for Ubiquitous Healthcare , 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[10]  W J Tompkins,et al.  Applications of artificial neural networks for ECG signal detection and classification. , 1993, Journal of electrocardiology.

[11]  Willis J. Tompkins,et al.  A Real-Time QRS Detection Algorithm , 1985, IEEE Transactions on Biomedical Engineering.

[12]  Ron Kohavi,et al.  A Study of Cross-Validation and Bootstrap for Accuracy Estimation and Model Selection , 1995, IJCAI.

[13]  Jeffrey M. Hausdorff,et al.  Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[14]  R. Stephenson A and V , 1962, The British journal of ophthalmology.

[15]  Y. Kim,et al.  A PDA-Based ECG Beat Detector for Home Cardiac Care , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[16]  Patrick E. McSharry,et al.  Advanced Methods And Tools for ECG Data Analysis , 2006 .