2‐(Het)aryl‐ N ‐phosphorylpyrrolidines via Cyclization of Phosphorus Acid Amides: A Regioselective Approach

[1]  A. Burilov,et al.  N-Phosphorylated Pyrrolidines: An Overview of Synthetic Approaches , 2020, Synthesis.

[2]  E. Zangrando,et al.  Novel Chiral PNNP Ligands with a Pyrrolidine Backbone - Application in the Fe-Catalyzed Asymmetric Transfer Hydrogenation of Ketones , 2019, European Journal of Inorganic Chemistry.

[3]  A. Burilov,et al.  Ring opening reactions of nitrogen heterocycles , 2019, Russian Chemical Reviews.

[4]  I. Sazykin,et al.  Acid-Catalyzed Intramolecular Imination / Nucleophilic Trapping of 4-Aminobutanal Derivatives: One-Pot Access to 2-(Pyrazolyl)pyrrolidines , 2019, European Journal of Organic Chemistry.

[5]  A. Burilov,et al.  Acid‐Catalyzed Cascade Reaction of 4‐Aminobutanal Derivatives with (Hetero)aromatic Nucleophiles: A Versatile One‐Pot Access to 2‐(Hetero)arylpyrrolidines. , 2019, ChemistrySelect.

[6]  I. Sazykin,et al.  Synthesis of Novel 2-(Het)arylpyrrolidine Derivatives and Evaluation of Their Anticancer and Anti-Biofilm Activity , 2019, Molecules.

[7]  S. van Calenbergh,et al.  Amino acid based prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents. , 2019, Bioorganic & medicinal chemistry.

[8]  岩佐博人 Levetiracetam , 2019, Reactions Weekly.

[9]  Jun‐An Ma,et al.  Zinc-Mediated Mannich-Type Reaction of 2,2,2-Trifluorodiazoethane with Imines: Access to β-CF3-Amines. , 2018, Organic letters.

[10]  S. Ito,et al.  gem-Digold Acetylide Complexes for Catalytic Intermolecular [4 + 2] Cycloaddition: Having Two Gold Centers Is Better for Asymmetric Catalysis. , 2018, Organic letters.

[11]  R. Badorrey,et al.  Diastereoselective Construction of the 6-Oxa-2-azabicyclo[3.2.1]octane Scaffold from Chiral α-Hydroxyaldehyde Derivatives by the Aza-Prins Reaction. , 2017, The Journal of organic chemistry.

[12]  G. Strukul,et al.  Pyrrolidine-Containing Bisphosphonates as Potential Anti-Resorption Bone Drugs. , 2017, Chemistry.

[13]  A. Brancale,et al.  ProTides of BVdU as potential anticancer agents upon efficient intracellular delivery of their activated metabolites , 2016, Bioorganic & medicinal chemistry letters.

[14]  D. A. Klumpp,et al.  Cyclizations of N-carbamoyl and N-thiocarbamoyl iminium ions leading to ring-fused heterocycles , 2016 .

[15]  I. Beletskaya,et al.  (S)-2-[(N-arylamino)methyl]pyrrolidines-Based Phosphoramidite P,N-Ligand Library for Asymmetric Metal-Catalyzed Allylic Substitution and Conjugate 1,4-Addition , 2016 .

[16]  B. Trost,et al.  A Ruthenium/Phosphoramidite-Catalyzed Asymmetric Interrupted Metallo-ene Reaction. , 2016, Journal of the American Chemical Society.

[17]  A. Burilov,et al.  Interaction of 2-Naphthol with γ-Ureidoacetals. A New Method for the Synthesis of 2-Arylpyrrolidines , 2014, Chemistry of Heterocyclic Compounds.

[18]  B. Trost,et al.  Enantioselective synthesis of 2,2-disubstituted tetrahydrofurans: palladium-catalyzed [3+2] cycloadditions of trimethylenemethane with ketones. , 2013, Angewandte Chemie.

[19]  P. Carroll,et al.  Synthesis of Chiral N‐Sulfonyl and N‐Phosphinoyl α‐Halo Aldimine Precursors , 2013 .

[20]  M. Terada,et al.  Relay Catalysis by a Ruthenium Complex–Chiral Brønsted Acid Binary Sytem for Ternary Reaction Sequence Involving Enantioselective Pictet–Spengler-Type Cyclization as the Key Step , 2013 .

[21]  M. Otto,et al.  Phosphoramidate Prodrugs of (−)-β-D-(2R,4R)-dioxolane-thymine (DOT) as Potent Anti-HIV Agents , 2012, Antiviral chemistry & chemotherapy.

[22]  E. Gorovits,et al.  Phosphorodiamidates as a promising new phosphate prodrug motif for antiviral drug discovery: application to anti-HCV agents. , 2011, Journal of medicinal chemistry.

[23]  B. Trost,et al.  Development of an asymmetric trimethylenemethane cycloaddition reaction: application in the enantioselective synthesis of highly substituted carbocycles. , 2011, Journal of the American Chemical Society.

[24]  J. Balzarini,et al.  Phosphoramidate ProTides of the anticancer agent FUDR successfully deliver the preformed bioactive monophosphate in cells and confer advantage over the parent nucleoside. , 2011, Journal of medicinal chemistry.

[25]  John Buckingham,et al.  Dictionary of alkaloids with CD-ROM , 2010 .

[26]  T. Tarragó,et al.  Activity‐Based Probes for Monitoring Postproline Protease Activity , 2009, Chembiochem : a European journal of chemical biology.

[27]  A. Brancale,et al.  The application of phosphoramidate protide technology to acyclovir confers anti-HIV inhibition. , 2009, Journal of medicinal chemistry.

[28]  C. Mcguigan,et al.  The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4'-azidocytidine (R1479). , 2009, Bioorganic & medicinal chemistry letters.

[29]  Xin Chen,et al.  Irreversible inhibition of dipeptidyl peptidase 8 by dipeptide-derived diaryl phosphonates. , 2007, Journal of medicinal chemistry.

[30]  B. Trost,et al.  Palladium-catalyzed asymmetric [3+2] cycloaddition of trimethylenemethane with imines. , 2007, Journal of the American Chemical Society.

[31]  C. Mcguigan,et al.  Application of the phosphoramidate ProTide approach to 4'-azidouridine confers sub-micromolar potency versus hepatitis C virus on an inactive nucleoside. , 2007, Journal of medicinal chemistry.

[32]  C. Gennari,et al.  Rh-catalyzed enantioselective conjugate addition of arylboronic acids with a dynamic library of chiral tropos phosphorus ligands. , 2007, Chemistry.

[33]  M. Yus,et al.  Nickel-catalysed addition of dialkylzinc reagents to N-phosphinoyl-and N-sulfonylimines , 2007 .

[34]  W. Coulter,et al.  Synthesis, kinetic evaluation, and utilization of a biotinylated dipeptide proline diphenyl phosphonate for the disclosure of dipeptidyl peptidase IV-like serine proteases. , 2006, Biochemical and biophysical research communications.

[35]  J. D. de Vries,et al.  Rh-catalyzed asymmetric hydrogenation of prochiral olefins with a dynamic library of chiral TROPOS phosphorus ligands. , 2005, Chemistry.

[36]  C. Gennari,et al.  Enantioselective conjugate addition of phenylboronic acid to enones catalysed by a chiral tropos/atropos rhodium complex at the coalescence temperature. , 2005, Chemical communications.

[37]  A. Côté,et al.  Enantioselective synthesis of β-amino alcohols and α-amino acids via a copper catalyzed addition of diorganozinc reagents to N-phosphinoylimines , 2005 .

[38]  S. H. Kim,et al.  Synthesis of N-Diethoxyphosphinyl-1,2,3,4-Tetrahydroisoquinolines , 2004 .

[39]  B. Feringa,et al.  Highly enantioselective conjugate additions of potassium organotrifluoroborates to enones by use of monodentate phosphoramidite ligands. , 2004, The Journal of organic chemistry.

[40]  C. Gennari,et al.  Rh-catalysed asymmetric hydrogenations with a dynamic library of chiral tropos phosphorus-ligands , 2004 .

[41]  H. Schoemaker,et al.  C-C Bond Formation via N-Phosphoryliminium Ions , 2004 .

[42]  M. Shi,et al.  One-pot aza-Baylis–Hillman reactions of arylaldehydes and diphenylphosphinamide with methyl vinyl ketone in the presence of TiCl4, PPh3, and Et3N , 2002 .

[43]  D. A. Klumpp,et al.  Chemistry of dicationic electrophiles: superacid-catalyzed reactions of amino acetals. , 2002, The Journal of organic chemistry.

[44]  Masakatsu Shibasaki,et al.  Catalytic Asymmetric Syntheses of ICI-199441 and CP-99994 Using Nitro-Mannich Reaction , 2002 .

[45]  A. Lambeir,et al.  Structure-activity relationship of diaryl phosphonate esters as potent irreversible dipeptidyl peptidase IV inhibitors. , 1999, Journal of medicinal chemistry.

[46]  M. Wills,et al.  A Novel Phosphinamide Catalyst for the Asymmetric Reduction of Ketones by Borane. , 1998, The Journal of organic chemistry.

[47]  R. Hulst,et al.  Synthesis and Application of New Chiral Ligands for the Asymmetric Borane Reduction of Prochiral Ketones , 1996 .

[48]  M. Choukrad,et al.  Asymmetric carbonylation of .alpha.-methylbenzyl bromide catalyzed by oxazaphospholane-palladium complexes under phase-transfer conditions , 1988 .

[49]  P. Monk,et al.  γ-Lactam analogues of penicillanic and carbapenicillanic acids , 1983 .

[50]  E. I. Matrosov,et al.  PHOSPHORIC, PHOSPHONIC, AND PHOSPHINIC ACID AMIDES AS BASES , 1982 .

[51]  H. Openshaw,et al.  174. Studies on phosphorylation. Part II. The reaction of dialkyl phosphites with polyhalogen compounds in presence of bases. A new method for the phosphorylation of amines , 1945 .