The carboxy terminal domain of RNA polymerase II and alternative splicing.
暂无分享,去创建一个
A. Kornblihtt | M. L. de la Mata | M. Muñoz | Manuel de la Mata | Alberto R Kornblihtt | Manuel J Muñoz
[1] I. Graham,et al. Effects of RNA secondary structure on alternative splicing of Pre-mRNA: Is folding limited to a region behind the transcribing RNA polymerase? , 1988, Cell.
[2] A. Kornblihtt. Coupling transcription and alternative splicing. , 2007, Advances in experimental medicine and biology.
[3] J. Ahringer,et al. Differential chromatin marking of introns and expressed exons by H3K36me3 , 2008, Nature Genetics.
[4] Dirk Eick,et al. Serine-7 of the RNA Polymerase II CTD Is Specifically Required for snRNA Gene Expression , 2007, Science.
[5] J. Manley,et al. Phosphorylated RNA polymerase II stimulates pre-mRNA splicing. , 1999, Genes & development.
[6] K. Neugebauer,et al. Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells , 2006, Nature Structural &Molecular Biology.
[7] A. Kornblihtt,et al. The connection between splicing and cancer , 2006, Journal of Cell Science.
[8] A. Kornblihtt,et al. A slow RNA polymerase II affects alternative splicing in vivo. , 2003, Molecular cell.
[9] M. Garcia-Blanco,et al. MAZ Elements Alter Transcription Elongation and Silencing of the Fibroblast Growth Factor Receptor 2 Exon IIIb* , 2004, Journal of Biological Chemistry.
[10] Francisco E. Baralle,et al. Genomic variants in exons and introns: identifying the splicing spoilers , 2004, Nature Reviews Genetics.
[11] T. Cooper,et al. Alternative splicing in disease. , 2007, Advances in experimental medicine and biology.
[12] Y. Osheim,et al. Splice site selection, rate of splicing, and alternative splicing on nascent transcripts. , 1988, Genes & development.
[13] M. Wickens,et al. The C-terminal domain of RNA polymerase II couples mRNA processing to transcription , 1997, Nature.
[14] S. Szostek,et al. Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program. , 2006, Genes & development.
[15] Daniel F Tardiff,et al. In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants. , 2006, Genes & development.
[16] A. Kornblihtt,et al. Promoter Architecture Modulates CFTR Exon 9 Skipping* , 2003, The Journal of Biological Chemistry.
[17] Christoforos Nikolaou,et al. Nucleosome positioning as a determinant of exon recognition , 2009, Nature Structural &Molecular Biology.
[18] X. Darzacq,et al. In vivo dynamics of RNA polymerase II transcription , 2007, Nature Structural &Molecular Biology.
[19] S. Buratowski,et al. Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3' end processing. , 2004, Molecular cell.
[20] B. Gómez-González,et al. Genome instability: a mechanistic view of its causes and consequences , 2008, Nature Reviews Genetics.
[21] D. Black,et al. Co-transcriptional splicing of constitutive and alternative exons. , 2009, RNA.
[22] Michael R Green,et al. Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene. , 2005, Molecular cell.
[23] B. O’Malley,et al. CoAA, a Nuclear Receptor Coactivator Protein at the Interface of Transcriptional Coactivation and RNA Splicing , 2004, Molecular and Cellular Biology.
[24] A. Kornblihtt,et al. RNA polymerase II C-terminal domain mediates regulation of alternative splicing by SRp20 , 2006, Nature Structural &Molecular Biology.
[25] J. Ahearn,et al. A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[26] J. Manley,et al. Pin1 modulates RNA polymerase II activity during the transcription cycle. , 2007, Genes & development.
[27] K. J. Hertel,et al. Linking Splicing to Pol II Transcription Stabilizes Pre-mRNAs and Influences Splicing Patterns , 2006, PLoS biology.
[28] D. Eick,et al. Conditional Expression of RNA Polymerase II in Mammalian Cells , 2000, The Journal of Biological Chemistry.
[29] Xiang-Dong Fu,et al. ASF/SF2-Regulated CaMKIIδ Alternative Splicing Temporally Reprograms Excitation-Contraction Coupling in Cardiac Muscle , 2005, Cell.
[30] J. Manley,et al. Pinning Down Transcription: Regulation of RNA Polymerase II Activity During the Cell Cycle , 2004, Cell cycle.
[31] G. Orphanides,et al. A Human RNA Polymerase II Complex Containing Factors That Modify Chromatin Structure , 1998, Molecular and Cellular Biology.
[32] K. Neugebauer,et al. Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex. , 2005, Molecular cell.
[33] A. Krainer,et al. Listening to silence and understanding nonsense: exonic mutations that affect splicing , 2002, Nature Reviews Genetics.
[34] R. Bronson,et al. SRp38 regulates alternative splicing and is required for Ca(2+) handling in the embryonic heart. , 2009, Developmental cell.
[35] K. Jones,et al. The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation. , 2008, Genes & development.
[36] G. Ast,et al. Different levels of alternative splicing among eukaryotes , 2006, Nucleic acids research.
[37] Peter J. Shepard,et al. The SR protein family , 2009, Genome Biology.
[38] M. Assanah,et al. HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer , 2010, Nature.
[39] T. Misteli,et al. RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo. , 1999, Molecular cell.
[40] M. Yaniv,et al. The human SWI/SNF subunit Brm is a regulator of alternative splicing , 2006, Nature Structural &Molecular Biology.
[41] B. Blencowe,et al. Analysis of the requirement for RNA polymerase II CTD heptapeptide repeats in pre-mRNA splicing and 3'-end cleavage. , 2004, RNA.
[42] B. Graveley. Alternative splicing: regulation without regulators , 2009, Nature Structural &Molecular Biology.
[43] T. Cooper,et al. Pre-mRNA splicing and human disease. , 2003, Genes & development.
[44] W. G. Kelly,et al. RNA polymerase II is a glycoprotein. Modification of the COOH-terminal domain by O-GlcNAc. , 1993, The Journal of biological chemistry.
[45] A. Kornblihtt,et al. First come, first served revisited: factors affecting the same alternative splicing event have different effects on the relative rates of intron removal. , 2010, RNA.
[46] D. Bentley,et al. Capping, splicing, and 3' processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD. , 2001, Genes & development.
[47] D. Eick,et al. Molecular evolution of the RNA polymerase II CTD. , 2008, Trends in genetics : TIG.
[48] A. Kornblihtt,et al. Antagonistic effects of T‐Ag and VP16 reveal a role for RNA pol II elongation on alternative splicing , 2001, The EMBO journal.
[49] Manuel de la Mata,et al. Control of alternative splicing through siRNA-mediated transcriptional gene silencing , 2009, Nature Structural &Molecular Biology.
[50] A. Krainer,et al. The gene encoding the splicing factor SF2/ASF is a proto-oncogene , 2007, Nature Structural &Molecular Biology.
[51] S. Buratowski. Progression through the RNA polymerase II CTD cycle. , 2009, Molecular cell.
[52] A. Kornblihtt,et al. Alternative splicing: multiple control mechanisms and involvement in human disease. , 2002, Trends in genetics : TIG.
[53] Dirk Eick,et al. Transcribing RNA Polymerase II Is Phosphorylated at CTD Residue Serine-7 , 2007, Science.
[54] S. Shuman,et al. Structure, mechanism, and evolution of the mRNA capping apparatus. , 2001, Progress in nucleic acid research and molecular biology.
[55] M. Alló,et al. Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing , 2009, Proceedings of the National Academy of Sciences.
[56] P. Cramer,et al. Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution , 2001, Science.
[57] Danny Reinberg,et al. Histones: annotating chromatin. , 2009, Annual review of genetics.
[58] P Cramer,et al. Functional association between promoter structure and transcript alternative splicing. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[59] R. Padgett,et al. Rates of in situ transcription and splicing in large human genes , 2009, Nature Structural &Molecular Biology.
[60] Shona Murphy,et al. Cracking the RNA polymerase II CTD code. , 2008, Trends in genetics : TIG.
[61] S. Masich,et al. In situ transcription and splicing in the Balbiani ring 3 gene , 2001, The EMBO journal.
[62] A. Krainer,et al. SR proteins function in coupling RNAP II transcription to pre-mRNA splicing. , 2007, Molecular cell.
[63] B. Frey,et al. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing , 2008, Nature Genetics.
[64] M. Garcia-Blanco,et al. The Carboxyl-terminal Domain of RNA Polymerase II Is Not Sufficient to Enhance the Efficiency of Pre-mRNA Capping or Splicing in the Context of a Different Polymerase* , 2009, Journal of Biological Chemistry.
[65] G. Ast,et al. Chromatin organization marks exon-intron structure , 2009, Nature Structural &Molecular Biology.
[66] S. Berget,et al. Participation of the C-Terminal Domain of RNA Polymerase II in Exon Definition during Pre-mRNA Splicing , 2000, Molecular and Cellular Biology.
[67] J. Manley,et al. Concurrent splicing and transcription are not sufficient to enhance splicing efficiency. , 2007, RNA.
[68] Eric T. Wang,et al. Alternative Isoform Regulation in Human Tissue Transcriptomes , 2008, Nature.
[69] D. Bentley,et al. "Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions. , 2009, Molecular cell.
[70] J. Ross,et al. Dilated cardiomyopathy caused by tissue‐specific ablation of SC35 in the heart , 2004, The EMBO journal.
[71] Dirk Eick,et al. TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II. , 2009, Molecular cell.
[72] A. Kornblihtt,et al. Promoter usage and alternative splicing. , 2005, Current opinion in cell biology.
[73] D. Bentley,et al. Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors. , 2005, Current opinion in cell biology.
[74] D. Bentley,et al. RNA Polymerase II Carboxy-Terminal Domain Phosphorylation Is Required for Cotranscriptional Pre-mRNA Splicing and 3′-End Formation , 2004, Molecular and Cellular Biology.
[75] H. Phatnani,et al. Phosphorylation and functions of the RNA polymerase II CTD. , 2006, Genes & development.
[76] A. Kornblihtt,et al. Transcriptional Activators Differ in Their Abilities to Control Alternative Splicing* , 2002, The Journal of Biological Chemistry.
[77] A. Kornblihtt,et al. Multiple links between transcription and splicing. , 2004, RNA.
[78] J. Manley,et al. Inactivation of the SR Protein Splicing Factor ASF/SF2 Results in Genomic Instability , 2005, Cell.
[79] Bert W O'Malley,et al. Coordinate Regulation of Transcription and Splicing by Steroid Receptor Coregulators , 2002, Science.
[80] D. Bentley,et al. 5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II. , 1997, Genes & development.
[81] Dirk Eick,et al. The last CTD repeat of the mammalian RNA polymerase II large subunit is important for its stability. , 2004, Nucleic acids research.
[82] M. Carmo-Fonseca,et al. The CTD role in cotranscriptional RNA processing and surveillance , 2008, FEBS letters.
[83] Anton Meinhart,et al. Recognition of RNA polymerase II carboxy-terminal domain by 3′-RNA-processing factors , 2004, Nature.
[84] A. Kornblihtt,et al. Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer. , 1999, Molecular cell.
[85] R. Reed,et al. Functional coupling of RNAP II transcription to spliceosome assembly. , 2006, Genes & development.
[86] Jean Y. J. Wang,et al. Nuclear c-Abl Is a COOH-Terminal Repeated Domain (CTD)-Tyrosine Kinase-specific for the Mammalian RNA Polymerase II: Possible Role in Transcription Elongation , 1999 .
[87] I. Poser,et al. SR protein family members display diverse activities in the formation of nascent and mature mRNPs in vivo. , 2009, Molecular cell.
[88] M. Hagmann,et al. RNA polymerase II C-terminal domain required for enhancer-driven transcription , 1995, Nature.
[89] B. Blencowe,et al. Regulation of Alternative Splicing by Histone Modifications , 2010, Science.