Reduction of lymphocyte G protein-coupled receptor kinase-2 (GRK2) after exercise training predicts survival in patients with heart failure
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P. Filardi | D. Leosco | F. Giallauria | W. Koch | C. Vigorito | D. Liccardo | G. Galasso | N. Ferrara | G. Furgi | G. Rengo | G. Pagano | G. Femminella | C. Marcianò | V. Parisi | A. Cannavo | C. Zincarelli | C. Lucia | G. D. Femminella
[1] D. Leosco,et al. Oral Anticoagulation Therapy in Heart Failure Patients in Sinus Rhythm: A Systematic Review and Meta-Analysis , 2013, PloS one.
[2] P. Filardi,et al. β-adrenergic receptors and G protein-coupled receptor kinase-2 in Alzheimer's disease: a new paradigm for prognosis and therapy? , 2013, Journal of Alzheimer's disease : JAD.
[3] P. Gargiulo,et al. Blockade of β‐adrenoceptors restores the GRK2‐mediated adrenal α2‐adrenoceptor–catecholamine production axis in heart failure , 2012, British journal of pharmacology.
[4] D. Leosco,et al. Myocardial β2‐adrenoceptor gene delivery promotes coordinated cardiac adaptive remodelling and angiogenesis in heart failure , 2012, British journal of pharmacology.
[5] H. Middlekauff,et al. Exercise training improves neurovascular control and functional capacity in heart failure patients regardless of age , 2012, European journal of preventive cardiology.
[6] D. Leosco,et al. Targeting the &bgr;-Adrenergic Receptor System Through G-Protein–Coupled Receptor Kinase 2: A New Paradigm for Therapy and Prognostic Evaluation in Heart Failure From Bench to Bedside , 2012, Circulation. Heart failure.
[7] M. van Brussel,et al. Effect of outpatient exercise training programmes in patients with chronic heart failure: a systematic review , 2012, European journal of preventive cardiology.
[8] T. Trikalinos,et al. Drug and Device Effects on Peak Oxygen Consumption, 6-Minute Walk Distance, and Natriuretic Peptides as Predictors of Therapeutic Effects on Mortality in Patients With Heart Failure and Reduced Ejection Fraction , 2011, Circulation. Heart failure.
[9] D. Leosco,et al. GRK2 as a novel gene therapy target in heart failure. , 2011, Journal of molecular and cellular cardiology.
[10] D. Leosco,et al. Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure. , 2010, American journal of physiology. Heart and circulatory physiology.
[11] D. Leosco,et al. The G protein coupled receptor kinase 2 plays an essential role in beta-adrenergic receptor-induced insulin resistance. , 2009, Cardiovascular research.
[12] W. Kraus,et al. Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial. , 2009, JAMA.
[13] W. Koch,et al. Myocardial Adeno-Associated Virus Serotype 6–&bgr;ARKct Gene Therapy Improves Cardiac Function and Normalizes the Neurohormonal Axis in Chronic Heart Failure , 2009, Circulation.
[14] S. Houser,et al. G Protein-Coupled Receptor Kinase 2 Ablation in Cardiac Myocytes Before or After Myocardial Infarction Prevents Heart Failure , 2008, Circulation research.
[15] F. Rengo,et al. Exercise promotes angiogenesis and improves beta-adrenergic receptor signalling in the post-ischaemic failing rat heart. , 2008, Cardiovascular research.
[16] F. Rengo,et al. Exercise training and beta-blocker treatment ameliorate age-dependent impairment of beta-adrenergic receptor signaling and enhance cardiac responsiveness to adrenergic stimulation. , 2007, American journal of physiology. Heart and circulatory physiology.
[17] M. Schalij,et al. Effect of exercise training on autonomic derangement and neurohumoral activation in chronic heart failure. , 2007, Journal of cardiac failure.
[18] D. Leosco,et al. Exercise training affects age-induced changes in SOD and heat shock protein expression in rat heart , 2006, Experimental Gerontology.
[19] F. Giallauria,et al. Reduction of N terminal-pro-brain (B-type) natriuretic peptide levels with exercise-based cardiac rehabilitation in patients with left ventricular dysfunction after myocardial infarction , 2006, European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology.
[20] F. Giallauria,et al. Long-term effects of cardiac rehabilitation on end-exercise heart rate recovery after myocardial infarction , 2006, European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology.
[21] W. Koch,et al. Lymphocyte levels of GRK2 (betaARK1) mirror changes in the LVAD-supported failing human heart: lower GRK2 associated with improved beta-adrenergic signaling after mechanical unloading. , 2006, Journal of cardiac failure.
[22] D. Leosco,et al. Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure. , 2005, European heart journal.
[23] S. Houser,et al. Improved Myocardial &bgr;-Adrenergic Responsiveness and Signaling With Exercise Training in Hypertension , 2005, Circulation.
[24] B. Yawn,et al. Trends in heart failure incidence and survival in a community-based population. , 2004, JAMA.
[25] M. Piepoli,et al. Exercise training in patients with chronic heart failure , 2004, BMJ : British Medical Journal.
[26] M. Piepoli,et al. Exercise training meta-analysis of trials in patients with chronic heart failure (ExTraMATCH) , 2004, BMJ : British Medical Journal.
[27] J. Port,et al. Effects of carvedilol on adrenergic receptor pharmacology in human ventricular myocardium and lymphocytes , 2004, The clinical investigator.
[28] P. Abete,et al. Exercise restores β-adrenergic vasorelaxation in aged rat carotid arteries , 2003 .
[29] P. Abete,et al. Exercise restores beta-adrenergic vasorelaxation in aged rat carotid arteries. , 2003, American journal of physiology. Heart and circulatory physiology.
[30] J. Cohn. The Sympathetic Nervous System in Heart Failure , 2002, Circulation.
[31] Daniel Levy,et al. Long-term trends in the incidence of and survival with heart failure. , 2002, The New England journal of medicine.
[32] Salim Yusuf,et al. Effects of exercise training in patients with heart failure: the Exercise Rehabilitation Trial (EXERT). , 2002, American heart journal.
[33] N. Dzimiri,et al. Characterization Of Lymphocyte β2‐Adrenoceptor Signalling In Patients With Left Ventricular Volume Overload Disease , 2002, Clinical and experimental pharmacology & physiology.
[34] Robert J. Lefkowitz,et al. Seven-transmembrane-spanning receptors and heart function , 2002, Nature.
[35] K. Werdan,et al. Impaired β-adrenergic control of immune function in patients with chronic heart failure: reversal by β1-blocker treatment , 2001, Basic Research in Cardiology.
[36] K. Werdan,et al. Impaired beta-adrenergic control of immune function in patients with chronic heart failure: reversal by beta1-blocker treatment. , 2001, Basic research in cardiology.
[37] G. Schuler,et al. Effects of exercise training on left ventricular function and peripheral resistance in patients with chronic heart failure: A randomized trial. , 2000, JAMA.
[38] R. Lefkowitz,et al. Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by beta-adrenergic receptor stimulation and blockade. , 1998, Circulation.
[39] R. Lefkowitz,et al. G protein-coupled receptor kinases. , 1998, Annual review of biochemistry.
[40] N. Dzimiri,et al. RELATIONSHIP BETWEEN ALTERATIONS IN LYMPHOCYTE AND MYOCARDIAL β‐ADRENOCEPTOR DENSITY IN PATIENTS WITH LEFT HEART VALVULAR DISEASE , 1996, Clinical and experimental pharmacology & physiology.
[41] M. Böhm,et al. Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart. , 1994, Circulation research.
[42] R. Lefkowitz. G protein—coupled receptor kinases , 1993, Cell.
[43] M. Böhm,et al. Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart. , 1993, Circulation.
[44] O. Brodde,et al. Human beta-adrenoceptors: relation of myocardial and lymphocyte beta-adrenoceptor density. , 1986, Science.