Effect of Growth Hormone on Skeletal Mass in Adult Dogs
暂无分享,去创建一个
THE skeletal mass of adult dogs of both sexes can be significantly increased by administering exogenous bovine growth hormone (0.5 mg/kg/day for 84 days) without inducing acromegaly or diabetes. This increase is a consequence of a marked rise in new bone formation. The new bone is histologically and microradiographically normal.
[1] R. Heaney. Evaluation and Interpretation of Calcium‐Kinetic Data in Man , 1963, Clinical orthopaedics and related research.
[2] A. Frantz,et al. Effects of Estrogen and Sex Difference on Secretion of Human Growth Hormone1 , 1965 .
[3] W. Harris,et al. Spatial and Temporal Variations in Cortical Bone Formation in Dogs: A LONG-TERM STUDY , 1968 .
[4] W. Harris,et al. Skeletal renewal and metabolic bone disease. , 1969, The New England journal of medicine.